Coverart for item
The Resource Alternatives to animal testing, editors, R.E. Hester and R.M. Harrison

Alternatives to animal testing, editors, R.E. Hester and R.M. Harrison

Label
Alternatives to animal testing
Title
Alternatives to animal testing
Statement of responsibility
editors, R.E. Hester and R.M. Harrison
Contributor
Subject
Genre
Language
eng
Summary
This product is not available separately, it is only sold as part of a set. There are 750 products in the set and these are all sold as one entity.
Member of
Cataloging source
OKU
Dewey number
615.9/07
Illustrations
illustrations
Index
index present
LC call number
RA1199.4.A46
LC item number
A48 2006
Literary form
non fiction
Nature of contents
  • dictionaries
  • bibliography
http://library.link/vocab/relatedWorkOrContributorDate
1948-
http://library.link/vocab/relatedWorkOrContributorName
  • Hester, R. E.
  • Harrison, Roy M.
Series statement
Issues in environmental science and technology,
Series volume
23
http://library.link/vocab/subjectName
  • Alternative toxicity testing
  • Animal experimentation
  • Chemistry
  • MEDICAL
  • Science
  • Alternative toxicity testing
  • Animal experimentation
Summary expansion
Animal experimentation has long been a controversial issue with impassioned arguments on both sides of the debate. Increasingly it has become more expedient and feasible to develop new methods that avoid the use of animals. There is agreement on both sides that reduction and refinement of experiments on animals should be an important goal for the industries involved. Alternatives to Animal Testing, written by leading experts in the field, discusses the issues involved and approaches that can be taken. Topics include; the safety evaluation of chemicals, international validation and barriers to the validation of alternative tests, in vitro testing for endocrine disruptors, intelligent approaches to safety evaluation of chemicals, alternative tests and the regulatory framework. The book provides an up-to-date discussion of the current state of development of alternatives to animal testing and is ideal for professionals and academics in the field. It would also be of use for graduate students wishing to pursue a career in the pharmaceutical and cosmetic industries
Label
Alternatives to animal testing, editors, R.E. Hester and R.M. Harrison
Instantiates
Publication
Bibliography note
Includes bibliographical references and index
Carrier category
online resource
Carrier category code
  • cr
Carrier MARC source
rdacarrier
Content category
text
Content type code
  • txt
Content type MARC source
rdacontent
Contents
GENERAL OVERVIEW OF THE SAFETY EVALUATION OF CHEMICALS / Paul Illing -- Introduction -- Legislation and regulatory requirements -- The regulatory paradigm -- The interface between toxicology and risk assessment -- Interpreting toxicology -- Conclusions -- References -- INTERNATIONAL VALIDATION AND BARRIERS TO THE VALIDATION OF ALTERNATIVE TESTS / Michael Balls -- Introduction -- Background to the validation process -- The validation process -- Problems being encountered in implementing the validation process -- The need for an invalidation process -- Concluding remarks -- References -- IN VITRO TESTING FOR ENDOCRINE DISRUPTORS / Robert D. Combes -- Introduction -- In silico approaches -- In vitro tests for EDs -- Discussion -- Conclusions -- Acknowledgment -- References -- iNTELLIGENT APPROACHES TO SAFETY EVALUATION / Derek J. Knight -- Introduction -- Hazardous properties assessment -- Risk assessment -- Existing studies and literature data -- Surrogate data: calculation, read across and SAR/QSAR -- Alternatives to animal toxicology studies -- Data waivers -- Expert reports and weight of evidence -- Preliminary risk assessments -- EU Registration, Evaluation and Registration Scheme (REACH) -- Data for REACH -- Regulatory planning & liaison with the regulators -- Common themes -- Acknowledgments -- References -- ALTERNATIVE TESTS AND THE 7TH AMENDMENT TO THE COSMETICS DIRECTIVE / Carl Westmoreland -- Introduction -- Overview of current approaches to risk assessment for cosmetics -- 7th Amendment to the EU Cosmetics Directive (76/768/EEC) -- Status of alternative tests -- Endpoints where risk assessment for cosmetics can be achieved without using animal data -- Endpoints where risk assessment for cosmetics cannot currently be achieved without using animal data -- New approaches to risk assessment without animals -- Acknowledgments -- Abbreviations -- References
Control code
229452937
Dimensions
unknown
Extent
1 online resource (x, 123 pages)
Form of item
online
Isbn
9781847552457
Media category
computer
Media MARC source
rdamedia
Media type code
  • c
Other control number
10.1039/9781847552457
Other physical details
illustrations
http://library.link/vocab/ext/overdrive/overdriveId
31789781847552457
Specific material designation
remote
System control number
(OCoLC)229452937
Label
Alternatives to animal testing, editors, R.E. Hester and R.M. Harrison
Publication
Bibliography note
Includes bibliographical references and index
Carrier category
online resource
Carrier category code
  • cr
Carrier MARC source
rdacarrier
Content category
text
Content type code
  • txt
Content type MARC source
rdacontent
Contents
GENERAL OVERVIEW OF THE SAFETY EVALUATION OF CHEMICALS / Paul Illing -- Introduction -- Legislation and regulatory requirements -- The regulatory paradigm -- The interface between toxicology and risk assessment -- Interpreting toxicology -- Conclusions -- References -- INTERNATIONAL VALIDATION AND BARRIERS TO THE VALIDATION OF ALTERNATIVE TESTS / Michael Balls -- Introduction -- Background to the validation process -- The validation process -- Problems being encountered in implementing the validation process -- The need for an invalidation process -- Concluding remarks -- References -- IN VITRO TESTING FOR ENDOCRINE DISRUPTORS / Robert D. Combes -- Introduction -- In silico approaches -- In vitro tests for EDs -- Discussion -- Conclusions -- Acknowledgment -- References -- iNTELLIGENT APPROACHES TO SAFETY EVALUATION / Derek J. Knight -- Introduction -- Hazardous properties assessment -- Risk assessment -- Existing studies and literature data -- Surrogate data: calculation, read across and SAR/QSAR -- Alternatives to animal toxicology studies -- Data waivers -- Expert reports and weight of evidence -- Preliminary risk assessments -- EU Registration, Evaluation and Registration Scheme (REACH) -- Data for REACH -- Regulatory planning & liaison with the regulators -- Common themes -- Acknowledgments -- References -- ALTERNATIVE TESTS AND THE 7TH AMENDMENT TO THE COSMETICS DIRECTIVE / Carl Westmoreland -- Introduction -- Overview of current approaches to risk assessment for cosmetics -- 7th Amendment to the EU Cosmetics Directive (76/768/EEC) -- Status of alternative tests -- Endpoints where risk assessment for cosmetics can be achieved without using animal data -- Endpoints where risk assessment for cosmetics cannot currently be achieved without using animal data -- New approaches to risk assessment without animals -- Acknowledgments -- Abbreviations -- References
Control code
229452937
Dimensions
unknown
Extent
1 online resource (x, 123 pages)
Form of item
online
Isbn
9781847552457
Media category
computer
Media MARC source
rdamedia
Media type code
  • c
Other control number
10.1039/9781847552457
Other physical details
illustrations
http://library.link/vocab/ext/overdrive/overdriveId
31789781847552457
Specific material designation
remote
System control number
(OCoLC)229452937

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