The Resource Alzheimer's disease : methods and protocols, edited by Nigel M. Hooper
Alzheimer's disease : methods and protocols, edited by Nigel M. Hooper
Resource Information
The item Alzheimer's disease : methods and protocols, edited by Nigel M. Hooper represents a specific, individual, material embodiment of a distinct intellectual or artistic creation found in University of Missouri Libraries.This item is available to borrow from 1 library branch.
Resource Information
The item Alzheimer's disease : methods and protocols, edited by Nigel M. Hooper represents a specific, individual, material embodiment of a distinct intellectual or artistic creation found in University of Missouri Libraries.
This item is available to borrow from 1 library branch.
- Summary
- With the molecular mechanisms underlying the various forms of muscular dystrophy now rapidly clarifying, precise diagnosis has become a reality, and even a requirement in clinical practice. In Muscular Dystrophy: Methods and Protocols, Katherine Bushby and Louise Anderson have assembled an outstanding collection of key techniques for the analysis of DNA and protein from patients suspected to suffer from muscular dystrophy. Each method is highly detailed to ensure success and is presented by a hands-on expert who uses it on a day-to-day basis. The various DNA techniques focus on both the X-linked muscular dystrophies and the autosomal recessive muscular dystrophies. The protein methods include expression analysis, multiplex western blot analysis, immunocytochemical analysis, and reviews of immunological reagants and of amplification systems. Also discussed are the use of animal models to understand human muscular dystrophy and the available options for gene-based therapy. Comprehensive and highly practical, Muscular Dystrophy: Methods and Protocols offers today{u0260}s diagnostic laboratories, basic and medical researchers, and active clinicians an authoritative collection of tools that will serve as exacting diagnostic tools as well as greatly empowering research on the novel therapeutics now beginning to emerge
- Language
- eng
- Extent
- 1 online resource (xiv, 408 pages)
- Note
- Source of title; title from Title page
- Contents
-
- Introduction to Alzheimer's disease / D. Allsop-The genetics of Alzheimer's disease / N. Brindle and P.S. George-Hyslop-Advances in methodology and current prospects for primary drug therapies for Alzheimer's disease / D.S. Knopman-Production and functional assays of recombinant secreted amyloid precursor protein (app) (sappalpha) / S.W. Barger-Quantifying abeta(1-40) and abeta (1-42) using sandwich-elisa / D.M. Skovronsky [and others]-Electrophoretic separation and immunoblotting of abeta(1-40) and abeta (1-42) / M. Staufenbiel and P.A. Paganetti-Abeta-induced proinflammatory cytokine release from differentiated human thp-1 monocytes / K.R. Brunden [and others]-Effects of the beta-amyloid peptide on membrane ion permeability / H.A. Pearson-Analysis of beta-amyloid peptide degradation in vitro / B. Cordell and A. Naidu-Posttranslational modifications of amyloid precursor protein : Ectodomain phosphorylation and sulfation / J. Walter and C. Haass-Posttranslational modifications of the amyloid precursor protein : Glycosylation / C. Liu [and others]-Using an amyloid precursor protein (app) reporter to characterize alpha-secretase / S.B. Roberts-Inhibition of alpha-secretase by zinc metalloproteinase inhibitors / S. Parvathy, A.J. Turner and N.M. Hooper-Development of neoepitope antibodies against the beta-secretase cleavage site in the amyloid precursor protein / C.W. Gray and E.H. Karran-Beta-secretase : Tissue culture studies of sequence specificity, inhibitors, and candidate enzymes / M. Citron-Using beta-secretase inhibitors to distiguish the generation of the abeta peptides terminating at val-40 and ala-42 / P.A. Paganetti and M. Staufenbiel-Designing animal models of Alzheimer's disease with amyloid precursor protein (app) transgenes / J.F. Loring-Phosphorylation of amyloid precursor protein (app) family proteins / T. Suzuki [and others]-Determining the transmembrane topology of the presenilins / G. Thinakaran and A. Doan-Normal proteolytic processing of the presenilins / H. Hartmann and B.A. Yankner-Apoptotic proteolytic cleavage of the presenilins by caspases / T.W. Kim-The phosphorylation of presenilin proteins / J. Walter-Interaction of the presenilins with the amyloid precursor protein (APP) / A. Weidemann [and others]-Distribution of presenilins and amyloid precursor protein (APP) in detergent-insoluble membrane domains / E.T. Parkin, A.J. Turner and N.M. Hooper-Characterization and use of monoclonal antibodies to tau and paired helical filament tau / P. Davies-Tau phosphorylation both in vitro and in cells / C.H. Reynolds, G.M. Gibb and S. Lovestone-Transglutaminase-catalyzed formation of Alzheimer-like insoluble complexes from recombinant tau / B.J. Balin and D.M. Appelt
- Isbn
- 9786610821556
- Label
- Alzheimer's disease : methods and protocols
- Title
- Alzheimer's disease
- Title remainder
- methods and protocols
- Statement of responsibility
- edited by Nigel M. Hooper
- Subject
-
- Brain Diseases
- Alzheimer Disease
- Alzheimer's disease -- Diagnosis
- Alzheimer's disease -- Diagnosis -- Laboratory manuals
- Alzheimer's disease -- Molecular aspects
- Alzheimer's disease -- Molecular aspects -- Laboratory manuals
- Amino Acids, Peptides, and Proteins
- Amyloid
- Amyloid beta-Protein Precursor
- Amyloidogenic Proteins
- Biological Science Disciplines
- Biology
- Neurodegenerative Diseases
- Protease Nexins
- Protein Precursors
- Proteinase Inhibitory Proteins, Secretory
- Proteins
- Psychiatry and Psychology
- Tauopathies
- Wetenschappelijke technieken
- Central Nervous System Diseases
- Dementia
- Disciplines and Occupations
- Disease
- Electronic books
- Electronic bookss
- Genetics
- HEALTH & FITNESS -- Diseases | General
- Laboratory manuals
- MEDICAL -- Clinical Medicine
- MEDICAL -- Diseases
- MEDICAL -- Evidence-Based Medicine
- MEDICAL -- Internal Medicine
- Membrane Proteins
- Mental Disorders
- Molecular diagnosis
- Molecular diagnosis -- Laboratory manuals
- Natural Science Disciplines
- Nervous System Diseases
- Neurocognitive Disorders
- Language
- eng
- Summary
- With the molecular mechanisms underlying the various forms of muscular dystrophy now rapidly clarifying, precise diagnosis has become a reality, and even a requirement in clinical practice. In Muscular Dystrophy: Methods and Protocols, Katherine Bushby and Louise Anderson have assembled an outstanding collection of key techniques for the analysis of DNA and protein from patients suspected to suffer from muscular dystrophy. Each method is highly detailed to ensure success and is presented by a hands-on expert who uses it on a day-to-day basis. The various DNA techniques focus on both the X-linked muscular dystrophies and the autosomal recessive muscular dystrophies. The protein methods include expression analysis, multiplex western blot analysis, immunocytochemical analysis, and reviews of immunological reagants and of amplification systems. Also discussed are the use of animal models to understand human muscular dystrophy and the available options for gene-based therapy. Comprehensive and highly practical, Muscular Dystrophy: Methods and Protocols offers today{u0260}s diagnostic laboratories, basic and medical researchers, and active clinicians an authoritative collection of tools that will serve as exacting diagnostic tools as well as greatly empowering research on the novel therapeutics now beginning to emerge
- Action
- digitized
- Cataloging source
- YUS
- http://bibfra.me/vocab/lite/collectionName
- Biomedprotocols
- Dewey number
- 616.8/31
- Illustrations
- illustrations
- Index
- index present
- Language note
- English
- LC call number
- RC523
- LC item number
- .A39746 2000
- Literary form
- non fiction
- Nature of contents
-
- dictionaries
- bibliography
- handbooks
- NLM call number
- WT 155
- NLM item number
- A47885 1999
- http://library.link/vocab/relatedWorkOrContributorName
-
- Hooper, N. M
- Humana Press
- Series statement
- Methods in molecular medicine
- Series volume
- 32
- http://library.link/vocab/subjectName
-
- Alzheimer's disease
- Alzheimer's disease
- Molecular diagnosis
- Proteins
- Biology
- Amyloidogenic Proteins
- Tauopathies
- Dementia
- Protein Precursors
- Protease Nexins
- Amyloid
- Brain Diseases
- Proteinase Inhibitory Proteins, Secretory
- Amino Acids, Peptides, and Proteins
- Neurodegenerative Diseases
- Neurocognitive Disorders
- Biological Science Disciplines
- Mental Disorders
- Central Nervous System Diseases
- Nervous System Diseases
- Natural Science Disciplines
- Disciplines and Occupations
- Psychiatry and Psychology
- Disease
- Membrane Proteins
- Amyloid beta-Protein Precursor
- Genetics
- Alzheimer Disease
- HEALTH & FITNESS
- MEDICAL
- MEDICAL
- MEDICAL
- MEDICAL
- Alzheimer's disease
- Alzheimer's disease
- Molecular diagnosis
- Wetenschappelijke technieken
- Label
- Alzheimer's disease : methods and protocols, edited by Nigel M. Hooper
- Note
- Source of title; title from Title page
- Antecedent source
- unknown
- Bibliography note
- Includes bibliographical references and index
- Carrier category
- online resource
- Carrier category code
-
- cr
- Carrier MARC source
- rdacarrier
- Color
- multicolored
- Content category
- text
- Content type code
-
- txt
- Content type MARC source
- rdacontent
- Contents
- Introduction to Alzheimer's disease / D. Allsop-The genetics of Alzheimer's disease / N. Brindle and P.S. George-Hyslop-Advances in methodology and current prospects for primary drug therapies for Alzheimer's disease / D.S. Knopman-Production and functional assays of recombinant secreted amyloid precursor protein (app) (sappalpha) / S.W. Barger-Quantifying abeta(1-40) and abeta (1-42) using sandwich-elisa / D.M. Skovronsky [and others]-Electrophoretic separation and immunoblotting of abeta(1-40) and abeta (1-42) / M. Staufenbiel and P.A. Paganetti-Abeta-induced proinflammatory cytokine release from differentiated human thp-1 monocytes / K.R. Brunden [and others]-Effects of the beta-amyloid peptide on membrane ion permeability / H.A. Pearson-Analysis of beta-amyloid peptide degradation in vitro / B. Cordell and A. Naidu-Posttranslational modifications of amyloid precursor protein : Ectodomain phosphorylation and sulfation / J. Walter and C. Haass-Posttranslational modifications of the amyloid precursor protein : Glycosylation / C. Liu [and others]-Using an amyloid precursor protein (app) reporter to characterize alpha-secretase / S.B. Roberts-Inhibition of alpha-secretase by zinc metalloproteinase inhibitors / S. Parvathy, A.J. Turner and N.M. Hooper-Development of neoepitope antibodies against the beta-secretase cleavage site in the amyloid precursor protein / C.W. Gray and E.H. Karran-Beta-secretase : Tissue culture studies of sequence specificity, inhibitors, and candidate enzymes / M. Citron-Using beta-secretase inhibitors to distiguish the generation of the abeta peptides terminating at val-40 and ala-42 / P.A. Paganetti and M. Staufenbiel-Designing animal models of Alzheimer's disease with amyloid precursor protein (app) transgenes / J.F. Loring-Phosphorylation of amyloid precursor protein (app) family proteins / T. Suzuki [and others]-Determining the transmembrane topology of the presenilins / G. Thinakaran and A. Doan-Normal proteolytic processing of the presenilins / H. Hartmann and B.A. Yankner-Apoptotic proteolytic cleavage of the presenilins by caspases / T.W. Kim-The phosphorylation of presenilin proteins / J. Walter-Interaction of the presenilins with the amyloid precursor protein (APP) / A. Weidemann [and others]-Distribution of presenilins and amyloid precursor protein (APP) in detergent-insoluble membrane domains / E.T. Parkin, A.J. Turner and N.M. Hooper-Characterization and use of monoclonal antibodies to tau and paired helical filament tau / P. Davies-Tau phosphorylation both in vitro and in cells / C.H. Reynolds, G.M. Gibb and S. Lovestone-Transglutaminase-catalyzed formation of Alzheimer-like insoluble complexes from recombinant tau / B.J. Balin and D.M. Appelt
- Control code
- 49851558
- Dimensions
- unknown
- Extent
- 1 online resource (xiv, 408 pages)
- File format
- unknown
- Form of item
- online
- Isbn
- 9786610821556
- Issuing body
- Digitization of Biomedprotocols made available on the world wide web by Humana Press.
- Lccn
- 99017627
- Level of compression
- unknown
- Media category
- computer
- Media MARC source
- rdamedia
- Media type code
-
- c
- Other control number
- 10.1385/1592591957
- Other physical details
- illustrations.
- Quality assurance targets
- unknown
- Reformatting quality
- unknown
- Reproduction note
- Electronic reproduction.
- Sound
- unknown sound
- Specific material designation
- remote
- System control number
- (OCoLC)49851558
- System details
- Master and use copy. Digital master created according to Benchmark for Faithful Digital Reproductions of Monographs and Serials, Version 1. Digital Library Federation, December 2002.
- Label
- Alzheimer's disease : methods and protocols, edited by Nigel M. Hooper
- Note
- Source of title; title from Title page
- Antecedent source
- unknown
- Bibliography note
- Includes bibliographical references and index
- Carrier category
- online resource
- Carrier category code
-
- cr
- Carrier MARC source
- rdacarrier
- Color
- multicolored
- Content category
- text
- Content type code
-
- txt
- Content type MARC source
- rdacontent
- Contents
- Introduction to Alzheimer's disease / D. Allsop-The genetics of Alzheimer's disease / N. Brindle and P.S. George-Hyslop-Advances in methodology and current prospects for primary drug therapies for Alzheimer's disease / D.S. Knopman-Production and functional assays of recombinant secreted amyloid precursor protein (app) (sappalpha) / S.W. Barger-Quantifying abeta(1-40) and abeta (1-42) using sandwich-elisa / D.M. Skovronsky [and others]-Electrophoretic separation and immunoblotting of abeta(1-40) and abeta (1-42) / M. Staufenbiel and P.A. Paganetti-Abeta-induced proinflammatory cytokine release from differentiated human thp-1 monocytes / K.R. Brunden [and others]-Effects of the beta-amyloid peptide on membrane ion permeability / H.A. Pearson-Analysis of beta-amyloid peptide degradation in vitro / B. Cordell and A. Naidu-Posttranslational modifications of amyloid precursor protein : Ectodomain phosphorylation and sulfation / J. Walter and C. Haass-Posttranslational modifications of the amyloid precursor protein : Glycosylation / C. Liu [and others]-Using an amyloid precursor protein (app) reporter to characterize alpha-secretase / S.B. Roberts-Inhibition of alpha-secretase by zinc metalloproteinase inhibitors / S. Parvathy, A.J. Turner and N.M. Hooper-Development of neoepitope antibodies against the beta-secretase cleavage site in the amyloid precursor protein / C.W. Gray and E.H. Karran-Beta-secretase : Tissue culture studies of sequence specificity, inhibitors, and candidate enzymes / M. Citron-Using beta-secretase inhibitors to distiguish the generation of the abeta peptides terminating at val-40 and ala-42 / P.A. Paganetti and M. Staufenbiel-Designing animal models of Alzheimer's disease with amyloid precursor protein (app) transgenes / J.F. Loring-Phosphorylation of amyloid precursor protein (app) family proteins / T. Suzuki [and others]-Determining the transmembrane topology of the presenilins / G. Thinakaran and A. Doan-Normal proteolytic processing of the presenilins / H. Hartmann and B.A. Yankner-Apoptotic proteolytic cleavage of the presenilins by caspases / T.W. Kim-The phosphorylation of presenilin proteins / J. Walter-Interaction of the presenilins with the amyloid precursor protein (APP) / A. Weidemann [and others]-Distribution of presenilins and amyloid precursor protein (APP) in detergent-insoluble membrane domains / E.T. Parkin, A.J. Turner and N.M. Hooper-Characterization and use of monoclonal antibodies to tau and paired helical filament tau / P. Davies-Tau phosphorylation both in vitro and in cells / C.H. Reynolds, G.M. Gibb and S. Lovestone-Transglutaminase-catalyzed formation of Alzheimer-like insoluble complexes from recombinant tau / B.J. Balin and D.M. Appelt
- Control code
- 49851558
- Dimensions
- unknown
- Extent
- 1 online resource (xiv, 408 pages)
- File format
- unknown
- Form of item
- online
- Isbn
- 9786610821556
- Issuing body
- Digitization of Biomedprotocols made available on the world wide web by Humana Press.
- Lccn
- 99017627
- Level of compression
- unknown
- Media category
- computer
- Media MARC source
- rdamedia
- Media type code
-
- c
- Other control number
- 10.1385/1592591957
- Other physical details
- illustrations.
- Quality assurance targets
- unknown
- Reformatting quality
- unknown
- Reproduction note
- Electronic reproduction.
- Sound
- unknown sound
- Specific material designation
- remote
- System control number
- (OCoLC)49851558
- System details
- Master and use copy. Digital master created according to Benchmark for Faithful Digital Reproductions of Monographs and Serials, Version 1. Digital Library Federation, December 2002.
Subject
- Brain Diseases
- Alzheimer Disease
- Alzheimer's disease -- Diagnosis
- Alzheimer's disease -- Diagnosis -- Laboratory manuals
- Alzheimer's disease -- Molecular aspects
- Alzheimer's disease -- Molecular aspects -- Laboratory manuals
- Amino Acids, Peptides, and Proteins
- Amyloid
- Amyloid beta-Protein Precursor
- Amyloidogenic Proteins
- Biological Science Disciplines
- Biology
- Neurodegenerative Diseases
- Protease Nexins
- Protein Precursors
- Proteinase Inhibitory Proteins, Secretory
- Proteins
- Psychiatry and Psychology
- Tauopathies
- Wetenschappelijke technieken
- Central Nervous System Diseases
- Dementia
- Disciplines and Occupations
- Disease
- Electronic books
- Electronic bookss
- Genetics
- HEALTH & FITNESS -- Diseases | General
- Laboratory manuals
- MEDICAL -- Clinical Medicine
- MEDICAL -- Diseases
- MEDICAL -- Evidence-Based Medicine
- MEDICAL -- Internal Medicine
- Membrane Proteins
- Mental Disorders
- Molecular diagnosis
- Molecular diagnosis -- Laboratory manuals
- Natural Science Disciplines
- Nervous System Diseases
- Neurocognitive Disorders
Genre
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<div class="citation" vocab="http://schema.org/"><i class="fa fa-external-link-square fa-fw"></i> Data from <span resource="http://link.library.missouri.edu/portal/Alzheimers-disease--methods-and-protocols/WMw38tdJw-g/" typeof="Book http://bibfra.me/vocab/lite/Item"><span property="name http://bibfra.me/vocab/lite/label"><a href="http://link.library.missouri.edu/portal/Alzheimers-disease--methods-and-protocols/WMw38tdJw-g/">Alzheimer's disease : methods and protocols, edited by Nigel M. Hooper</a></span> - <span property="potentialAction" typeOf="OrganizeAction"><span property="agent" typeof="LibrarySystem http://library.link/vocab/LibrarySystem" resource="http://link.library.missouri.edu/"><span property="name http://bibfra.me/vocab/lite/label"><a property="url" href="http://link.library.missouri.edu/">University of Missouri Libraries</a></span></span></span></span></div>
