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The Resource Animal models for neurodegenerative disease, edited by Jésus Avila, Jose J. Lucas and Félix Hernández

Animal models for neurodegenerative disease, edited by Jésus Avila, Jose J. Lucas and Félix Hernández

Label
Animal models for neurodegenerative disease
Title
Animal models for neurodegenerative disease
Statement of responsibility
edited by Jésus Avila, Jose J. Lucas and Félix Hernández
Contributor
Subject
Language
eng
Summary
"In recent years, medical developments have resulted in an increase in human life expectancy. Some developed countries now have a larger population of individuals aged over 64 than those under 14. One consequence of the ageing population is a higher incidence of certain neurodegenerative disorders. In order to prevent these, we need to learn more about them. This book provides up-to-date information on the use of transgenic mouse models in the study of neurodegenerative disorders such as Alzheimer's and Huntington's disease. By reproducing some of the pathological aspects of the diseases, these studies could reveal the mechanism for their onset or development. Some of the transgenic mice can also be used as targets for testing new compounds with the potential to prevent or combat these disorders. The editors have extensive knowledge and experience in this field and the book is aimed at undergraduates, postgraduates and academics. The chapters cover disorders including: Alzheimer's disease, Parkinson's disease, Huntington's and other CAG diseases, amyotrophic lateral sclerosis (ALS), recessive ataxias, disease caused by prions, and ischemia."--Publisher description
Member of
Cataloging source
IXA
Illustrations
illustrations
Index
index present
LC call number
RC523
LC item number
.A65 2011
Literary form
non fiction
Nature of contents
bibliography
http://library.link/vocab/relatedWorkOrContributorName
  • Avila, Jesús
  • Hernández Perez, Félix
  • Lucas, José J
  • Royal Society of Chemistry (Great Britain)
Series statement
RSC Drug Discovery Series
Series volume
no. 6
http://library.link/vocab/subjectName
  • Alzheimer's disease
  • Animal models in research
  • Huntington's disease
  • Nervous system
  • Parkinson's disease
Label
Animal models for neurodegenerative disease, edited by Jésus Avila, Jose J. Lucas and Félix Hernández
Instantiates
Publication
Bibliography note
Includes bibliographical references and index
Carrier category
volume
Carrier category code
nc
Carrier MARC source
rdacarrier
Content category
text
Content type code
txt
Content type MARC source
rdacontent
Contents
Ch. 1. The Contribution of Transgenic Models to the Understanding of Alzheimer's Disease Progression and Therapeutic Development / Meredith A. Chabrier, Kara M. Neely, Nicholas A. Castello and Frank M. LaFerla -- Ch. 2 Animal Models of Amyloid/PS-1 Pathology / Akihiko Takashima -- Ch. 3. The Ying and Yang of the Reelin Signalling Pathway in Alzheimer's Disease Pathology / Eduardo Soriano, Daniela Rossi and Lluís Pujadas -- Ch. 4. Transgenic Mice Overexpressing GSK-3[beta] as Animal Models for Alzheimer's Disease / Félix Hernández -- Ch. 5. Invertebrate and Vertebrate Models of Tauopathies / Jügen Götz, Lars M. Ittner, Naeman N. Götz, Hong Lam and Hannah R. Nicholas -- Ch. 6. Animal Models of Parkinson's Disease / Hardy J. Rideout and Leonidas Stefanis -- Ch. 7. Animal Models and the Pathogenesis of Parkinson's Disease / José G. Castaño, Teresa Iglesias and Justo G. de Yébenes -- Ch. 8. Neuroprotection in Parkinson's Disease / Alberto Pascual, Javier Villadiego, María Hidalgo-Figueroa, Simón Méndez-Ferrer, Raquel Gómez-Díaz, Juan José Toledo-Aral and José Lopez-Barneo -- Ch. 9. Animal Models for ALS / Ritsuko Fujii and Toru Takumi -- Ch. 10. Animal Models for Huntington's Disease / Zaira Ortega and José J. Lucas -- Ch. 11. Mouse Models of Prion Protein Related Diseases / María Gasset and Adriano Aguzzi -- Ch. 12. Mouse Models of Ischemia / David C. Henshall and Roger P. Simon -- Ch. 13. A Non-transgenic Rat Model of Sporadic Alzheimer's Disease / Khalid Iqbal, Xiaochuan Wang, Julie Blanchard and Inge Grundke-Iqbal
Control code
756503142
Dimensions
24 cm
Extent
xv, 290 pages
Isbn
9781849731843
Media category
unmediated
Media MARC source
rdamedia
Media type code
n
Other physical details
illustrations
System control number
(OCoLC)756503142
Label
Animal models for neurodegenerative disease, edited by Jésus Avila, Jose J. Lucas and Félix Hernández
Publication
Bibliography note
Includes bibliographical references and index
Carrier category
volume
Carrier category code
nc
Carrier MARC source
rdacarrier
Content category
text
Content type code
txt
Content type MARC source
rdacontent
Contents
Ch. 1. The Contribution of Transgenic Models to the Understanding of Alzheimer's Disease Progression and Therapeutic Development / Meredith A. Chabrier, Kara M. Neely, Nicholas A. Castello and Frank M. LaFerla -- Ch. 2 Animal Models of Amyloid/PS-1 Pathology / Akihiko Takashima -- Ch. 3. The Ying and Yang of the Reelin Signalling Pathway in Alzheimer's Disease Pathology / Eduardo Soriano, Daniela Rossi and Lluís Pujadas -- Ch. 4. Transgenic Mice Overexpressing GSK-3[beta] as Animal Models for Alzheimer's Disease / Félix Hernández -- Ch. 5. Invertebrate and Vertebrate Models of Tauopathies / Jügen Götz, Lars M. Ittner, Naeman N. Götz, Hong Lam and Hannah R. Nicholas -- Ch. 6. Animal Models of Parkinson's Disease / Hardy J. Rideout and Leonidas Stefanis -- Ch. 7. Animal Models and the Pathogenesis of Parkinson's Disease / José G. Castaño, Teresa Iglesias and Justo G. de Yébenes -- Ch. 8. Neuroprotection in Parkinson's Disease / Alberto Pascual, Javier Villadiego, María Hidalgo-Figueroa, Simón Méndez-Ferrer, Raquel Gómez-Díaz, Juan José Toledo-Aral and José Lopez-Barneo -- Ch. 9. Animal Models for ALS / Ritsuko Fujii and Toru Takumi -- Ch. 10. Animal Models for Huntington's Disease / Zaira Ortega and José J. Lucas -- Ch. 11. Mouse Models of Prion Protein Related Diseases / María Gasset and Adriano Aguzzi -- Ch. 12. Mouse Models of Ischemia / David C. Henshall and Roger P. Simon -- Ch. 13. A Non-transgenic Rat Model of Sporadic Alzheimer's Disease / Khalid Iqbal, Xiaochuan Wang, Julie Blanchard and Inge Grundke-Iqbal
Control code
756503142
Dimensions
24 cm
Extent
xv, 290 pages
Isbn
9781849731843
Media category
unmediated
Media MARC source
rdamedia
Media type code
n
Other physical details
illustrations
System control number
(OCoLC)756503142

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