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The Resource Biocatalysis in organic synthesis : the retrosynthesis approach, Nicholas J. Turner and Luke Humphreys

Biocatalysis in organic synthesis : the retrosynthesis approach, Nicholas J. Turner and Luke Humphreys

Label
Biocatalysis in organic synthesis : the retrosynthesis approach
Title
Biocatalysis in organic synthesis
Title remainder
the retrosynthesis approach
Statement of responsibility
Nicholas J. Turner and Luke Humphreys
Creator
Contributor
Author
Subject
Genre
Language
eng
Summary
"The application of biocatalysis in organic synthesis is rapidly gaining popularity amongst chemists. Compared to traditional synthetic methodologies biocatalysis offers a number of advantages in terms of enhanced selectivity (chemo-, regio-, stereo- ), reduced environmental impact and lower cost of starting materials. Together these advantages can contribute to more sustainable manufacturing processes across a wide range of industries ranging from pharmaceuticals to biofuels. The biocatalytic toolbox has expanded significantly in the past five years and given the current rate of development of new engineered biocatalysts it is likely that the number of available biocatalysts will double in the next few years. This textbook gives a comprehensive overview of the current biocatalytic toolbox and also establishes new guidelines or rules for 'biocatalytic retrosynthesis'. Retrosynthesis is a well known and commonly used technique whereby organic chemists start with the structure of their target molecule and generate potential starting materials and intermediates through a series of retrosynthetic disconnections. These disconnections are then used to devise a forward synthesis, in this case using biocatalytic transformations in some of the key steps. Target molecules are disconnected with consideration for applying biocatalysts, as well as chemical reagents and chemocatalysts, in the forward synthesis direction. Using this textbook, students will be able to place biocatalysis within the context of other synthetic transformations that they have learned earlier in their studies. This additional awareness of biocatalysis will equip students for the modern world of organic synthesis where biocatalysts play an increasingly important role. In addition to guidelines for identifying where biocatalysts can be applied in organic synthesis, this textbook also provides examples of current applications of biocatalysis using worked examples and case studies. Tutorials enable the reader to practice disconnecting target molecules to find the 'hidden' biocatalytic reactions which can be applied in the synthetic direction. The book contains a complete description of the current biocatalyst classes that are available for use and also suggests areas where new enzymes are likely to be developed in the next few years"--Page 4 of cover
Cataloging source
YDX
http://library.link/vocab/creatorName
Turner, N. J.
Dewey number
572/.45
Illustrations
illustrations
Index
index present
LC call number
  • QD262
  • QD262
LC item number
  • .T868 2018
  • .T87 2018
Literary form
non fiction
Nature of contents
bibliography
http://library.link/vocab/relatedWorkOrContributorName
Humphreys, Luke
http://library.link/vocab/subjectName
  • Organic compounds
  • Biocatalysis
  • Biocatalysis
  • Organic compounds
Label
Biocatalysis in organic synthesis : the retrosynthesis approach, Nicholas J. Turner and Luke Humphreys
Instantiates
Publication
Copyright
Bibliography note
Includes bibliographical references and index
Carrier category
volume
Carrier category code
  • nc
Carrier MARC source
rdacarrier
Content category
  • text
  • still image
Content type code
  • txt
  • sti
Content type MARC source
  • rdacontent
  • rdacontent
Contents
Introduction and aims of the book -- Biocatalysis basics and principles -- Hydrolysis -- Reverse hydrolysis -- Reduction -- Oxidation -- C-X bond formation -- C-C bond formation -- Miscellaneous Biocatalysts -- Biocatalytic disconnections and functional group interconversions -- Comparison of different biocatalytic routes to target molecules -- Applications of biocatalytic retrosynthesis
Control code
959595941
Dimensions
24 cm
Extent
x, 429 pages
Isbn
9781782625308
Lccn
2018302857
Media category
unmediated
Media MARC source
rdamedia
Media type code
  • n
Other control number
99976642929
Other physical details
illustrations (some color)
System control number
(OCoLC)959595941
Label
Biocatalysis in organic synthesis : the retrosynthesis approach, Nicholas J. Turner and Luke Humphreys
Publication
Copyright
Bibliography note
Includes bibliographical references and index
Carrier category
volume
Carrier category code
  • nc
Carrier MARC source
rdacarrier
Content category
  • text
  • still image
Content type code
  • txt
  • sti
Content type MARC source
  • rdacontent
  • rdacontent
Contents
Introduction and aims of the book -- Biocatalysis basics and principles -- Hydrolysis -- Reverse hydrolysis -- Reduction -- Oxidation -- C-X bond formation -- C-C bond formation -- Miscellaneous Biocatalysts -- Biocatalytic disconnections and functional group interconversions -- Comparison of different biocatalytic routes to target molecules -- Applications of biocatalytic retrosynthesis
Control code
959595941
Dimensions
24 cm
Extent
x, 429 pages
Isbn
9781782625308
Lccn
2018302857
Media category
unmediated
Media MARC source
rdamedia
Media type code
  • n
Other control number
99976642929
Other physical details
illustrations (some color)
System control number
(OCoLC)959595941

Library Locations

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      38.944491 -92.326012
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