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The Resource Biochemistry of zinc, Ananda S. Prasad

Biochemistry of zinc, Ananda S. Prasad

Label
Biochemistry of zinc
Title
Biochemistry of zinc
Statement of responsibility
Ananda S. Prasad
Creator
Subject
Language
eng
Summary
Remarkable progress has occurred over the past 30 years in the study of zinc metabolism in humans, as researchers continue to investigate zinc's important nutritional and immunological roles in the body. Zinc deficiency has been linked to numerous immune deficiency disorders and to growth retardation in children and adolescents. In addition, zinc has proven to be an effective therapy for Wilson's disease and the once fatal acrodermatitis enteropathica. Biochemistry of Zinc critically examines these and other significant advances in basic research and relates them to the biological results of insufficient amounts of zinc in the body. This comprehensive text describes several recently discovered effects of zinc deficiency - such as anergy, and decreased levels of IL-2 and IL-1 production, natural killer cell activity, and active thymulin peptide - and assesses their clinical implications in the treatment of zinc-related immune disorders. It covers all the vital biochemical information on zinc and its functions, including its interactions with enzymes, hormones, lipid metabolism, cells, neurobiology, and other micronutrients. The book also discusses the relevant historical aspects of zinc and features an informative chapter on techniques for measuring zinc in biological samples, using atomic absorption spectrophotometry. Providing a solid foundation for future research, Biochemistry of Zinc is a thorough, state-of-the-art resource for researchers and students in biochemistry, nutrition, and medical research, as well as physicians who are likely to encounter zinc-related problems in their practice
Member of
Cataloging source
DNLM/DLC
http://library.link/vocab/creatorName
Prasad, Ananda S.
Illustrations
illustrations
Index
index present
Literary form
non fiction
Nature of contents
bibliography
Series statement
Biochemistry of the elements
Series volume
v. 11
http://library.link/vocab/subjectName
  • Zinc
  • Zinc
  • Zinc
  • Zinc
Label
Biochemistry of zinc, Ananda S. Prasad
Instantiates
Publication
Bibliography note
Includes bibliographical references and index
Carrier category
volume
Carrier category code
  • nc
Carrier MARC source
rdacarrier
Content category
text
Content type code
  • txt
Content type MARC source
rdacontent
Contents
Historical aspects of zinc -- Zinc deficiency in microorganisms, plants and animals -- Zinc deficiency in humans -- Zinc and enzymes -- Functions of zinc in metalloenzymes -- Binding sites of zinc in enzymes -- DNA and RNA polymerases -- Role of zinc in protection of essential thiol enzymes -- Cytochrome c oxidase -- Enzyme changes in zinc deficiency -- Enzymes involved in nucleic acids -- Alkaline phosphatase -- Zinc and gene expression -- Zinc fingers: a novel protein motif for gene expression -- Repetitive Zn-binding domains in TFIIIA -- Zinc: a necessary cofactor for domain binding to DNA -- GAL genes of Saccharomyces cerevisiae -- Hormone receptors -- Biochemistry of metallothionein -- Classification -- Primary structure -- Metal-binding sites -- Spatial structure -- Inducibility of metallothionein -- Molecular mechanisms of metallothionein induction -- Functional aspects -- Zinc and hormones -- Zinc and growth -- Zinc and reproductive functions -- Zinc and glucose metabolism -- Zinc and adrenals -- Zinc and prolactin -- Zinc and thyroid and parathyroid hormones -- Zinc and brain hormones -- Zinc and lipid metabolism -- Essential fatty acids -- Cholesterol -- Phospholipids -- Triglycerides -- Lipoproteins -- Lipid peroxidation -- Zinc and cells -- Lymphocytes -- Mast cells -- Platelets -- Macrophages and polymorphonuclear granulocytes -- Ecto 5'-nucleotidase -- Zinc and free radicals -- Zinc and erythrocytes -- Transport of zinc across the erythrocyte membrane -- Sickle-cell membranes and Zn2 -- Zinc and neurobiology -- Zinc and cell division -- Zinc and tubulin -- Zinc and brain function -- Zinc homeostasis -- Zinc-related enzymes in the brain -- Zinc and the hippocampus -- Zinc and human brain -- Zinc and epilepsy -- Zinc and immunity -- Studies in animal models -- Zinc deficiency and immune functions in humans -- Metabolism in zinc -- Dietary sources of zinc -- Absorption -- Intake and excretion of zinc -- Excretion of zinc -- Requirements for zinc -- Peripheral utilization -- Blood transport: zinc in plasma and red cells -- Homeostasis of zinc -- Clinical spectrum of human zinc deficiency -- Severe manifestations of zinc deficiency -- Moderate deficiency of zinc -- Zinc deficiency in sickle-cell disease -- Mild deficiency of zinc -- Miscellaneous clinical conditions -- Interactions of zinc with other micronutrients -- Interactions of zinc and iron in humans -- Zinc and copper -- Manganese and zinc -- Cadmium, lead and zinc -- Calcium and zinc -- Magnesium and zinc -- Sodium and zinc -- Vitamin A and zinc -- Vitamin B6 and zinc -- Vitamin D and zinc -- Vitamin E and zinc -- Folic acid and zinc -- Biotin and zinc -- Techniques for measurement of zinc in biological samples -- Determination of zinc in plasma -- Zinc in platelets, lymphocytes and granulocytes by flameless atomic absorption spectrophotometry
Control code
28889262
Dimensions
24 cm
Extent
xiii, 303 pages
Isbn
9780306443992
Media category
unmediated
Media MARC source
rdamedia
Media type code
  • n
Other physical details
illustrations
System control number
(WaOLN)1583500
Label
Biochemistry of zinc, Ananda S. Prasad
Publication
Bibliography note
Includes bibliographical references and index
Carrier category
volume
Carrier category code
  • nc
Carrier MARC source
rdacarrier
Content category
text
Content type code
  • txt
Content type MARC source
rdacontent
Contents
Historical aspects of zinc -- Zinc deficiency in microorganisms, plants and animals -- Zinc deficiency in humans -- Zinc and enzymes -- Functions of zinc in metalloenzymes -- Binding sites of zinc in enzymes -- DNA and RNA polymerases -- Role of zinc in protection of essential thiol enzymes -- Cytochrome c oxidase -- Enzyme changes in zinc deficiency -- Enzymes involved in nucleic acids -- Alkaline phosphatase -- Zinc and gene expression -- Zinc fingers: a novel protein motif for gene expression -- Repetitive Zn-binding domains in TFIIIA -- Zinc: a necessary cofactor for domain binding to DNA -- GAL genes of Saccharomyces cerevisiae -- Hormone receptors -- Biochemistry of metallothionein -- Classification -- Primary structure -- Metal-binding sites -- Spatial structure -- Inducibility of metallothionein -- Molecular mechanisms of metallothionein induction -- Functional aspects -- Zinc and hormones -- Zinc and growth -- Zinc and reproductive functions -- Zinc and glucose metabolism -- Zinc and adrenals -- Zinc and prolactin -- Zinc and thyroid and parathyroid hormones -- Zinc and brain hormones -- Zinc and lipid metabolism -- Essential fatty acids -- Cholesterol -- Phospholipids -- Triglycerides -- Lipoproteins -- Lipid peroxidation -- Zinc and cells -- Lymphocytes -- Mast cells -- Platelets -- Macrophages and polymorphonuclear granulocytes -- Ecto 5'-nucleotidase -- Zinc and free radicals -- Zinc and erythrocytes -- Transport of zinc across the erythrocyte membrane -- Sickle-cell membranes and Zn2 -- Zinc and neurobiology -- Zinc and cell division -- Zinc and tubulin -- Zinc and brain function -- Zinc homeostasis -- Zinc-related enzymes in the brain -- Zinc and the hippocampus -- Zinc and human brain -- Zinc and epilepsy -- Zinc and immunity -- Studies in animal models -- Zinc deficiency and immune functions in humans -- Metabolism in zinc -- Dietary sources of zinc -- Absorption -- Intake and excretion of zinc -- Excretion of zinc -- Requirements for zinc -- Peripheral utilization -- Blood transport: zinc in plasma and red cells -- Homeostasis of zinc -- Clinical spectrum of human zinc deficiency -- Severe manifestations of zinc deficiency -- Moderate deficiency of zinc -- Zinc deficiency in sickle-cell disease -- Mild deficiency of zinc -- Miscellaneous clinical conditions -- Interactions of zinc with other micronutrients -- Interactions of zinc and iron in humans -- Zinc and copper -- Manganese and zinc -- Cadmium, lead and zinc -- Calcium and zinc -- Magnesium and zinc -- Sodium and zinc -- Vitamin A and zinc -- Vitamin B6 and zinc -- Vitamin D and zinc -- Vitamin E and zinc -- Folic acid and zinc -- Biotin and zinc -- Techniques for measurement of zinc in biological samples -- Determination of zinc in plasma -- Zinc in platelets, lymphocytes and granulocytes by flameless atomic absorption spectrophotometry
Control code
28889262
Dimensions
24 cm
Extent
xiii, 303 pages
Isbn
9780306443992
Media category
unmediated
Media MARC source
rdamedia
Media type code
  • n
Other physical details
illustrations
System control number
(WaOLN)1583500

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