The Resource Cardiovascular adaptability influences cortical neuronal activation in very old adults, by Melanie A. Pearson

Cardiovascular adaptability influences cortical neuronal activation in very old adults, by Melanie A. Pearson

Label
Cardiovascular adaptability influences cortical neuronal activation in very old adults
Title
Cardiovascular adaptability influences cortical neuronal activation in very old adults
Statement of responsibility
by Melanie A. Pearson
Creator
Subject
Language
eng
Summary
The purpose of this research was to investigate the relationship between changes in the adaptability of the cardiovascular system and brain function in older adults. Eighteen young adults (21-28 years) and 33 older adults (65-81 years) observed a checkerboard reversing at different stimulation frequencies while cortical responses from the visual cortex were measured using event-related optical signals (EROS). Heart rate and blood pressure (BP) were recorded during a 5-minute sitting baseline and a 3-minute standing period. All participants also completed a neuropsychological assessment. The expected age-related decline in cognitive abilities was found; however, in this study, cognitive function was not influenced by any cardiovascular factors. Compared to the younger adults, the amplitude of the EROS response was significantly reduced in the older adults. Interestingly, a significant positive correlation between the factor representing Standing BP and EROS amplitude indicated that in adults over age 74 years, impaired BP responses to standing contribute to functional declines in cortical neuronal responses to visual stimulation. This finding is discussed within the context of the pathological model that brain function in older adults can be detrimentally affected by short-lived periods of inadequate blood flow to the brain. The protective benefits of fitness levels on brain function was also explored and discussed
Additional physical form
Also available on the Internet.
Cataloging source
MUU
http://library.link/vocab/creatorDate
1974-
http://library.link/vocab/creatorName
Pearson, Melanie A.
Degree
Ph. D.
Dissertation year
2004.
Government publication
government publication of a state province territory dependency etc
Granting institution
University of Missouri-Columbia
Illustrations
illustrations
Index
no index present
Literary form
non fiction
Nature of contents
  • bibliography
  • theses
http://library.link/vocab/subjectName
  • Cardiovascular diseases in old age
  • Older people
  • Blood
  • Brain
Target audience
specialized
Label
Cardiovascular adaptability influences cortical neuronal activation in very old adults, by Melanie A. Pearson
Instantiates
Publication
Note
  • Typescript
  • Vita
Bibliography note
Includes bibliographical references (leaves 63-70)
Carrier category
online resource
Carrier category code
  • cr
Carrier MARC source
rdacarrier
Content category
text
Content type code
  • txt
Content type MARC source
rdacontent
Control code
57439815
Dimensions
29 cm
Dimensions
unknown
Extent
ix, 71 leaves
Media category
computer
Media MARC source
rdamedia
Media type code
  • c
Other physical details
illustrations (some color)
Specific material designation
remote
Label
Cardiovascular adaptability influences cortical neuronal activation in very old adults, by Melanie A. Pearson
Publication
Note
  • Typescript
  • Vita
Bibliography note
Includes bibliographical references (leaves 63-70)
Carrier category
online resource
Carrier category code
  • cr
Carrier MARC source
rdacarrier
Content category
text
Content type code
  • txt
Content type MARC source
rdacontent
Control code
57439815
Dimensions
29 cm
Dimensions
unknown
Extent
ix, 71 leaves
Media category
computer
Media MARC source
rdamedia
Media type code
  • c
Other physical details
illustrations (some color)
Specific material designation
remote

Library Locations

    • University of Missouri Libraries DepositoryBorrow it
      2908 Lemone Blvd, Columbia, MO, 65211, US
      38.919360 -92.291620
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