Coverart for item
The Resource Cellular signal transduction in toxicology and pharmacology : data collection, analysis, and interpretation, edited by Jonathan W. Boyd (West Virginia University, Morgantown, WV, US), Richard R. Neubig (Michigan State University, MI, US)

Cellular signal transduction in toxicology and pharmacology : data collection, analysis, and interpretation, edited by Jonathan W. Boyd (West Virginia University, Morgantown, WV, US), Richard R. Neubig (Michigan State University, MI, US)

Label
Cellular signal transduction in toxicology and pharmacology : data collection, analysis, and interpretation
Title
Cellular signal transduction in toxicology and pharmacology
Title remainder
data collection, analysis, and interpretation
Statement of responsibility
edited by Jonathan W. Boyd (West Virginia University, Morgantown, WV, US), Richard R. Neubig (Michigan State University, MI, US)
Contributor
Editor
Subject
Language
eng
Summary
Covering a key topic due to growing research into the role of signaling mechanisms in toxicology, this book focuses on practical approaches for informatics, big data, and complex data sets. Combines fundamentals / basics with experimental applications that can help those involved in preclinical drug studies and translational research Includes detailed presentations of study methodology and data collection, analysis, and interpretation Discusses tools like experimental design, sample handling, analytical measurement techniques
Member of
Cataloging source
DLC
Dewey number
571.7/4
Index
index present
LC call number
QP517.C45
Literary form
non fiction
Nature of contents
  • dictionaries
  • bibliography
NLM call number
QU 375
http://library.link/vocab/relatedWorkOrContributorDate
1975-
http://library.link/vocab/relatedWorkOrContributorName
  • Boyd, Jonathan W.
  • Neubig, Richard R.
http://library.link/vocab/subjectName
  • Cellular signal transduction
  • Molecular toxicology
  • Molecular pharmacology
  • Cell Physiological Phenomena
  • Toxicology
  • Pharmacology
  • Mechanotransduction, Cellular
  • SCIENCE
  • Cellular signal transduction
  • Molecular pharmacology
  • Molecular toxicology
Label
Cellular signal transduction in toxicology and pharmacology : data collection, analysis, and interpretation, edited by Jonathan W. Boyd (West Virginia University, Morgantown, WV, US), Richard R. Neubig (Michigan State University, MI, US)
Instantiates
Publication
Bibliography note
Includes bibliographical references and index
Carrier category
online resource
Carrier category code
  • nc
Carrier MARC source
rdacarrier
Content category
text
Content type code
  • txt
Content type MARC source
rdacontent
Contents
  • Intro; Title Page; Copyright Page; Contents; List of Contributors; About the Editors; Preface; Chapter 1 Introduction to Cellular Signal Transduction: The Connection Between a Biological System and Its Surroundings; 1.1 Starting Big, but Ending Small; 1.1.1 Key Features of Signal Transduction; 1.2 Responding to Our Environment: Sensory Perception Begins and Ends with Signal Transduction; 1.2.1 Taste (Gustation); 1.2.2 Smell (Olfaction); 1.2.3 Sight (Vision); 1.2.4 Sound (Audition); 1.2.5 Touch (Somatosensation); 1.3 Primary Transport Systems Involved in Signal Transduction
  • 1.3.1 Ion Channels, Transporters, and Ion Pumps1.3.2 Receptors; 1.3.3 Endocytosis; 1.3.4 Exosomes; 1.4 Key Organelles Involved in Signal Transduction; 1.4.1 Mitochondria; 1.4.2 Endoplasmic Reticulum; 1.4.3 Nucleus; References; Chapter 2 Mechanisms of Cellular Signal Transduction; 2.1 Posttranslational Modifications and Their Roles in Signal Transduction; 2.1.1 Phosphorylation; 2.1.2 Acylation; 2.1.3 Alkylation; 2.1.4 Glycosylation; 2.1.5 Other PTMs; 2.2 Receptors; 2.3 Receptor Signaling Mechanisms; 2.3.1 Basic Principles of Signal Transduction Mechanisms; 2.3.1.1 Selectivity and Recognition
  • 2.3.1.2 Flexible Modularity2.3.1.3 Molecular Switches; 2.3.1.4 GPCRs and Second Messengers; 2.3.1.5 Amplification; 2.3.1.6 Turn-Off Mechanisms; 2.3.1.7 Localization; 2.3.1.8 Biased Signaling/Functional Selectivity; 2.4 Receptor Tyrosine Kinases; 2.5 Steroid Receptors; 2.6 Reactive Oxygen Species (ROS); 2.7 Summary; References; Chapter 3 From Cellular Mechanisms to Physiological Responses: Functional Signal Integration Across Multiple Biological Levels; 3.1 Introduction; 3.2 Cellular Information Flow: Mechanisms of Cellular Signal Integration and Regulation
Control code
1081386262
Edition
First edition.
Extent
1 online resource
Form of item
online
Isbn
9781119060208
Lccn
2019000424
Media category
computer
Media MARC source
rdamedia
Media type code
  • n
Specific material designation
remote
System control number
(OCoLC)1081386262
Label
Cellular signal transduction in toxicology and pharmacology : data collection, analysis, and interpretation, edited by Jonathan W. Boyd (West Virginia University, Morgantown, WV, US), Richard R. Neubig (Michigan State University, MI, US)
Publication
Bibliography note
Includes bibliographical references and index
Carrier category
online resource
Carrier category code
  • nc
Carrier MARC source
rdacarrier
Content category
text
Content type code
  • txt
Content type MARC source
rdacontent
Contents
  • Intro; Title Page; Copyright Page; Contents; List of Contributors; About the Editors; Preface; Chapter 1 Introduction to Cellular Signal Transduction: The Connection Between a Biological System and Its Surroundings; 1.1 Starting Big, but Ending Small; 1.1.1 Key Features of Signal Transduction; 1.2 Responding to Our Environment: Sensory Perception Begins and Ends with Signal Transduction; 1.2.1 Taste (Gustation); 1.2.2 Smell (Olfaction); 1.2.3 Sight (Vision); 1.2.4 Sound (Audition); 1.2.5 Touch (Somatosensation); 1.3 Primary Transport Systems Involved in Signal Transduction
  • 1.3.1 Ion Channels, Transporters, and Ion Pumps1.3.2 Receptors; 1.3.3 Endocytosis; 1.3.4 Exosomes; 1.4 Key Organelles Involved in Signal Transduction; 1.4.1 Mitochondria; 1.4.2 Endoplasmic Reticulum; 1.4.3 Nucleus; References; Chapter 2 Mechanisms of Cellular Signal Transduction; 2.1 Posttranslational Modifications and Their Roles in Signal Transduction; 2.1.1 Phosphorylation; 2.1.2 Acylation; 2.1.3 Alkylation; 2.1.4 Glycosylation; 2.1.5 Other PTMs; 2.2 Receptors; 2.3 Receptor Signaling Mechanisms; 2.3.1 Basic Principles of Signal Transduction Mechanisms; 2.3.1.1 Selectivity and Recognition
  • 2.3.1.2 Flexible Modularity2.3.1.3 Molecular Switches; 2.3.1.4 GPCRs and Second Messengers; 2.3.1.5 Amplification; 2.3.1.6 Turn-Off Mechanisms; 2.3.1.7 Localization; 2.3.1.8 Biased Signaling/Functional Selectivity; 2.4 Receptor Tyrosine Kinases; 2.5 Steroid Receptors; 2.6 Reactive Oxygen Species (ROS); 2.7 Summary; References; Chapter 3 From Cellular Mechanisms to Physiological Responses: Functional Signal Integration Across Multiple Biological Levels; 3.1 Introduction; 3.2 Cellular Information Flow: Mechanisms of Cellular Signal Integration and Regulation
Control code
1081386262
Edition
First edition.
Extent
1 online resource
Form of item
online
Isbn
9781119060208
Lccn
2019000424
Media category
computer
Media MARC source
rdamedia
Media type code
  • n
Specific material designation
remote
System control number
(OCoLC)1081386262

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