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The Resource Circulating nucleic acids in plasma and serum IV, edited by R. Swaminathan, Asif Butt, and Peter Gahan

Circulating nucleic acids in plasma and serum IV, edited by R. Swaminathan, Asif Butt, and Peter Gahan

Label
Circulating nucleic acids in plasma and serum IV
Title
Circulating nucleic acids in plasma and serum IV
Statement of responsibility
edited by R. Swaminathan, Asif Butt, and Peter Gahan
Contributor
Subject
Genre
Language
eng
Summary
"An accurate, inexpensive, and noninvasive method for the early diagnosis of cancer has been something of a holy grail among cancer researchers, but until recently a method meeting all three criteria has been elusive. Nucleic acids were first discovered in circulation in 1948, but it was not until the 1960s and 70s that patients with autoimmune disease and cancer were discovered to have higher levels of circulating DNA than were detected in in healthy persons. The focus in this volume is on three major applications of the circulating nucleic acids detection method: cancer, fetal medicine, and diseases such as diabetes, stroke, and myocardial infarction. In addition, there are reports on the biology and origins of circulating DNA and RNA and on improved methods for the detection of nucleic acids in plasma and serum. The circulating DNA found in cancer patients has many characteristics in common with their tumors, which made it an attractive candidate for use in the diagnosis and management of patients with malignancies. This method can also be applied to the assessment of the sublinical tumor burden in cancer patients, thus reducing the risk of unnecessary chemotherapy. Detection of nucleic acids circulating in maternal serum means that fetal diagnosis may be possible without resorting to the more dangerous and invasive methods now used (e.g., amniotic fluid and chorionic villus sampling). Detection of problems in the pregnancy such as preeclampsia and intrauterine growth retardation may also become possible through maternal blood samples. In diabetic patients, circulating nucleic acids can be used for the early detection of developments such as retinopathy. The benefits of using circulating nucleic acids in the diagnosis and management of cancer and chronic disease will be realized through earlier detection by means of this less expensive and less invasive testing technique and through its potential for closer monitoring of the disease."--Publisher's website
Member of
Additional physical form
Also issued on the Internet.
Cataloging source
DNLM/DLC
Illustrations
illustrations
Index
index present
LC call number
QP620
LC item number
.I53 2005
Literary form
non fiction
Nature of contents
bibliography
NLM call number
QU 58
NLM item number
I606 2006
http://library.link/vocab/relatedWorkOrContributorDate
2005
http://library.link/vocab/relatedWorkOrContributorName
  • Swaminathan, R.
  • Butt, Asif
  • Gahan, Peter B
  • New York Academy of Sciences
  • International Symposium on Circulating Nucleic Acids in Plasma/Serum
Series statement
Annals of the New York Academy of Sciences,
Series volume
v. 1075
http://library.link/vocab/subjectName
  • Nucleic acids
  • Blood
  • Tumor markers
  • Nucleic Acids
  • Biomarkers, Tumor
Label
Circulating nucleic acids in plasma and serum IV, edited by R. Swaminathan, Asif Butt, and Peter Gahan
Instantiates
Publication
Note
"This volume is the result of a meeting entitled: Fourth International Conference on Circulating Nucleic Acids in Plasma/Serum (CNAPS-IV), held on September 4-6, 2005 in the Franklin-Wilkins Building of Kings College in London, UK."--Contents p
Bibliography note
Includes bibliographical references and index
Carrier category
volume
Carrier category code
  • nc
Carrier MARC source
rdacarrier
Content category
text
Content type code
  • txt
Content type MARC source
rdacontent
Contents
Circulating nucleic acids in plasma and serum: recent developments -- Prehistory of the notion of circulating nucleic acids in plasma/serum (CNAPS): birth of a hypothesis -- Circulating DNA: intracellular and intraorgan messenger? -- Immunological aspects of circulating DNA -- Biology of circulating mRNA: still more questions than answers? -- Investigation of the origin of extracellular RNA in human cell culture -- Hypoxia-induced membrane-bound apoptotic DNA particles: potential mechanism of fetal DNA in maternal plasma -- Fetal nucleic acids in maternal body fluids: an update -- Fetal DNA in maternal plasma: progress through epigenetics -- Cell-free DNA in maternal plasma: is it all a question of size? -- Fetal blood group genotyping: present and future -- Placental RNA in maternal plasma: toward noninvasive fetal gene expression profiling -- Development and application of a real-time quantitative PCR for prenatal detection of fetal alpha(0)-thalassemia from maternal plasma -- Detection of a paternally inherited fetal mutation in maternal plasma by the use of automated sequencing -- Occurrence of neutrophil extracellular DNA traps (NETs) in pre-eclampsia: a link with elevated levels of cell-free DNA? -- Use of bi-allelic insertion/deletion polymorphisms as a positive control for fetal genotyping in maternal blood: first clinical experience -- PLAC1 mRNA in maternal blood correlates with Doppler waveform in uterine arteries in normal pregnancies at the second and third trimester -- Different approaches for noninvasive prenatal diagnosis of genetic diseases based on PNA-mediated enriched PCR -- Detection of SNPs in the plasma of pregnant women and in the urine of kidney transplant recipients by mass spectrometry -- Noninvasive prenatal diagnostic assay for the detection of beta-thalassemia -- Circulating DNA and lung cancer -- Circulating nucleic acids in plasma/serum and tumor progression: are apoptotic bodies involved? An experimental study in a rat cancer model -- Plasma RNA integrity analysis: methodology and validation -- Molecular diagnostic markers for lung cancer in sputum and plasma -- Quantitative analysis of plasma DNA in colorectal cancer patients: a novel prognostic tool -- Circulating DNA and DNase activity in human blood -- Comparative analysis of mesenteric and peripheral blood circulating tumor DNA in colorectal cancer patients -- Real-time quantification of human telomerase reverse transcriptase mRNA in the plasma of patients with prostate cancer -- Epigenetic analysis of body fluids and tumor tissues: application of a comprehensive molecular assessment for early-stage breast cancer patients -- Comparison of genetic alterations detected in circulating microsatellite DNA in blood plasma samples of patients with prostate cancer and benign prostatic hyperplasia -- Quantification of total plasma cell-free DNA in ovarian cancer using real-time PCR -- Cell-free DNA and RNA in plasma as a new molecular marker for prostate and breast cancer -- Early and specific prediction of the therapeutic efficacy in non-small cell lung cancer patients by nucleosomal DNA and cytokeratin-19 fragments -- Circulating nucleic acids and diabetic complications -- Circulating nucleic acids and critical illness -- Cell-free DNA levels as a prognostic marker in acute myocardial infarction -- MALDI-TOF mass spectrometry for quantitative, specific, and sensitive analysis of DNA and RNA -- Rapid prenatal diagnosis by QF-PCR: evaluation of 30,000 consecutive clinical samples and future applications -- Higher amount of free circulating DNA in serum than in plasma is not mainly caused by contaminated extraneous DNA during separation -- Improvement of methods for the isolation of cell-free fetal DNA from maternal plasma: comparison of a manual and an automated method -- The importance of careful blood processing in isolation of cell-free DNA -- Nucleosomal DNA fragments in autoimmune diseases -- Concentrations of circulating RNA from healthy donors and cancer patients estimated by different methods -- Isolation and comparative study of cell-free nucleic acids from human urine -- Influence of mycoplasma contamination on the concentration and composition of extracellular RNA -- Optimized real-time quantitative PCR measurement of male fetal DNA in maternal plasma
Control code
70119683
Dimensions
24 cm
Dimensions
unknown
Extent
xiv, 353 pages
Isbn
9781573316279
Isbn Type
(alk. paper)
Lccn
2006018862
Media category
unmediated
Media MARC source
rdamedia
Media type code
  • n
Other control number
9781573316279
Other physical details
illustrations
Specific material designation
remote
Label
Circulating nucleic acids in plasma and serum IV, edited by R. Swaminathan, Asif Butt, and Peter Gahan
Publication
Note
"This volume is the result of a meeting entitled: Fourth International Conference on Circulating Nucleic Acids in Plasma/Serum (CNAPS-IV), held on September 4-6, 2005 in the Franklin-Wilkins Building of Kings College in London, UK."--Contents p
Bibliography note
Includes bibliographical references and index
Carrier category
volume
Carrier category code
  • nc
Carrier MARC source
rdacarrier
Content category
text
Content type code
  • txt
Content type MARC source
rdacontent
Contents
Circulating nucleic acids in plasma and serum: recent developments -- Prehistory of the notion of circulating nucleic acids in plasma/serum (CNAPS): birth of a hypothesis -- Circulating DNA: intracellular and intraorgan messenger? -- Immunological aspects of circulating DNA -- Biology of circulating mRNA: still more questions than answers? -- Investigation of the origin of extracellular RNA in human cell culture -- Hypoxia-induced membrane-bound apoptotic DNA particles: potential mechanism of fetal DNA in maternal plasma -- Fetal nucleic acids in maternal body fluids: an update -- Fetal DNA in maternal plasma: progress through epigenetics -- Cell-free DNA in maternal plasma: is it all a question of size? -- Fetal blood group genotyping: present and future -- Placental RNA in maternal plasma: toward noninvasive fetal gene expression profiling -- Development and application of a real-time quantitative PCR for prenatal detection of fetal alpha(0)-thalassemia from maternal plasma -- Detection of a paternally inherited fetal mutation in maternal plasma by the use of automated sequencing -- Occurrence of neutrophil extracellular DNA traps (NETs) in pre-eclampsia: a link with elevated levels of cell-free DNA? -- Use of bi-allelic insertion/deletion polymorphisms as a positive control for fetal genotyping in maternal blood: first clinical experience -- PLAC1 mRNA in maternal blood correlates with Doppler waveform in uterine arteries in normal pregnancies at the second and third trimester -- Different approaches for noninvasive prenatal diagnosis of genetic diseases based on PNA-mediated enriched PCR -- Detection of SNPs in the plasma of pregnant women and in the urine of kidney transplant recipients by mass spectrometry -- Noninvasive prenatal diagnostic assay for the detection of beta-thalassemia -- Circulating DNA and lung cancer -- Circulating nucleic acids in plasma/serum and tumor progression: are apoptotic bodies involved? An experimental study in a rat cancer model -- Plasma RNA integrity analysis: methodology and validation -- Molecular diagnostic markers for lung cancer in sputum and plasma -- Quantitative analysis of plasma DNA in colorectal cancer patients: a novel prognostic tool -- Circulating DNA and DNase activity in human blood -- Comparative analysis of mesenteric and peripheral blood circulating tumor DNA in colorectal cancer patients -- Real-time quantification of human telomerase reverse transcriptase mRNA in the plasma of patients with prostate cancer -- Epigenetic analysis of body fluids and tumor tissues: application of a comprehensive molecular assessment for early-stage breast cancer patients -- Comparison of genetic alterations detected in circulating microsatellite DNA in blood plasma samples of patients with prostate cancer and benign prostatic hyperplasia -- Quantification of total plasma cell-free DNA in ovarian cancer using real-time PCR -- Cell-free DNA and RNA in plasma as a new molecular marker for prostate and breast cancer -- Early and specific prediction of the therapeutic efficacy in non-small cell lung cancer patients by nucleosomal DNA and cytokeratin-19 fragments -- Circulating nucleic acids and diabetic complications -- Circulating nucleic acids and critical illness -- Cell-free DNA levels as a prognostic marker in acute myocardial infarction -- MALDI-TOF mass spectrometry for quantitative, specific, and sensitive analysis of DNA and RNA -- Rapid prenatal diagnosis by QF-PCR: evaluation of 30,000 consecutive clinical samples and future applications -- Higher amount of free circulating DNA in serum than in plasma is not mainly caused by contaminated extraneous DNA during separation -- Improvement of methods for the isolation of cell-free fetal DNA from maternal plasma: comparison of a manual and an automated method -- The importance of careful blood processing in isolation of cell-free DNA -- Nucleosomal DNA fragments in autoimmune diseases -- Concentrations of circulating RNA from healthy donors and cancer patients estimated by different methods -- Isolation and comparative study of cell-free nucleic acids from human urine -- Influence of mycoplasma contamination on the concentration and composition of extracellular RNA -- Optimized real-time quantitative PCR measurement of male fetal DNA in maternal plasma
Control code
70119683
Dimensions
24 cm
Dimensions
unknown
Extent
xiv, 353 pages
Isbn
9781573316279
Isbn Type
(alk. paper)
Lccn
2006018862
Media category
unmediated
Media MARC source
rdamedia
Media type code
  • n
Other control number
9781573316279
Other physical details
illustrations
Specific material designation
remote

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