Coverart for item
The Resource Clostridium difficile : methods and protocols, edited by Peter Mullany and Adam P. Roberts

Clostridium difficile : methods and protocols, edited by Peter Mullany and Adam P. Roberts

Label
Clostridium difficile : methods and protocols
Title
Clostridium difficile
Title remainder
methods and protocols
Statement of responsibility
edited by Peter Mullany and Adam P. Roberts
Contributor
Subject
Genre
Language
eng
Summary
"Clostridium difficile is a major nosocomial pathogen and has been shown to be a primary cause of antibiotic-associated disease. Recently, there has been an emergence of highly transmissible and frequently antibiotic-resistant strains, and the organism has become a considerable burden on health-care systems worldwide. At the same time, there has been a dramatic increase in our ability to study the organism. This book brings together the key workers in C. difficile research to describe the recently developed methods for studying the organism. These range from methods for isolation of the organism, molecular typing, genomics, genetic manipulation, and the use of animal models. We are now therefore in a position to gain an in-depth understanding of how this organism is transmitted and how it causes disease."--Page v
Member of
Cataloging source
GW5XE
Dewey number
614.5120721
Illustrations
illustrations
Index
index present
Language note
English
LC call number
QR201.C54
LC item number
C56 2010
Literary form
non fiction
Nature of contents
  • dictionaries
  • bibliography
NLM call number
  • W1
  • QW 25
NLM item number
ME9616J v.646 2010
http://library.link/vocab/relatedWorkOrContributorDate
1959-
http://library.link/vocab/relatedWorkOrContributorName
  • Mullany, Peter
  • Roberts, Adam P
Series statement
  • Methods in molecular biology,
  • Springer protocols
Series volume
646
http://library.link/vocab/subjectName
  • Clostridium difficile
  • Clostridium difficile
  • Bacteriology
  • Life sciences
  • Medical laboratories
  • Microbiology
  • Pathology
  • Biology
  • Microbiology & Immunology
  • Health & Biological Sciences
Label
Clostridium difficile : methods and protocols, edited by Peter Mullany and Adam P. Roberts
Instantiates
Publication
Bibliography note
Includes bibliographical references and index
Carrier category
online resource
Carrier category code
  • cr
Carrier MARC source
rdacarrier
Color
multicolored
Content category
text
Content type code
  • txt
Content type MARC source
rdacontent
Contents
Part I. Introduction to Clostridium difficile and the disease it causes -- 1. Clostridium difficile : no longer an enigmatic pathogen? / Adam P. Roberts and Peter Mullany -- 2. Clostridium difficile and the disease it causes / Torbjörn Norén -- Part II. Isolation and culture techniques -- 3. Clostridium difficile isolation and culture techniques / Mike Wren -- Part III. Methods for typing and epidemiological studies -- 4. Molecular typing methods for Clostridium difficile : pulsed-field gel electrophoresis and PCR ribotyping / Sandra Janezic and Maja Rupnik -- 5. Clostridium difficile toxinotyping / Maja Rupnik -- 6. Multilocus sequence typing for Clostridium difficile / Ludovic Lemée and Jean-Louis Pons -- Part IV. Biochemistry of the organism -- 7. Molecular methods to study transcriptional regulation of Clostridium difficile toxin genes / Ana Antunes and Bruno Dupuy -- 8. Dissecting the cell surface / Robert Fagan and Neil Fairweather -- 9. Human intestinal epithelial response(s) to Clostridium difficile / Nazila V. Jafari, Elaine Allan, and Mona Bajaj-Elliott -- Part V. Genomics -- 10. Comparative genome analysis of Clostridium difficile using DNA microarrays / Richard Stabler, Lisa Dawson, and Brendan Wren -- Part VI. Development of systems for genetic analysis of the organism -- 11. ClosTron-targeted mutagenesis / John T. Heap, Stephen T. Cartman, Sarah A. Kuehne, Clare Cooksley, and Nigel P. Minton -- 12. Methods for gene cloning and targeted mutagenesis / Glen P. Carter, Dena Lyras, Rachael Poon, Pauline M. Howarth, and Julian I. Rood -- 13. Transposon mutagenesis in Clostridium difficile / Haitham A. Hussain, Adam P. Roberts, Rachael Whalan, and Peter Mullany -- Part VII. Animal models of disease -- 14. Refinement of the hamster model of Clostridium difficile disease / Gillian Douce and David Goulding -- 15. Methods for working with the mouse model / Anne Collignon
Control code
658898979
Dimensions
unknown
Extent
1 online resource (x, 241 pages)
Form of item
online
Isbn
9781603273657
Media category
computer
Media MARC source
rdamedia
Media type code
  • c
Other control number
10.1007/978-1-60327-365-7
Other physical details
illustrations.
http://library.link/vocab/ext/overdrive/overdriveId
978-1-60327-364-0
Specific material designation
remote
System control number
(OCoLC)658898979
Label
Clostridium difficile : methods and protocols, edited by Peter Mullany and Adam P. Roberts
Publication
Bibliography note
Includes bibliographical references and index
Carrier category
online resource
Carrier category code
  • cr
Carrier MARC source
rdacarrier
Color
multicolored
Content category
text
Content type code
  • txt
Content type MARC source
rdacontent
Contents
Part I. Introduction to Clostridium difficile and the disease it causes -- 1. Clostridium difficile : no longer an enigmatic pathogen? / Adam P. Roberts and Peter Mullany -- 2. Clostridium difficile and the disease it causes / Torbjörn Norén -- Part II. Isolation and culture techniques -- 3. Clostridium difficile isolation and culture techniques / Mike Wren -- Part III. Methods for typing and epidemiological studies -- 4. Molecular typing methods for Clostridium difficile : pulsed-field gel electrophoresis and PCR ribotyping / Sandra Janezic and Maja Rupnik -- 5. Clostridium difficile toxinotyping / Maja Rupnik -- 6. Multilocus sequence typing for Clostridium difficile / Ludovic Lemée and Jean-Louis Pons -- Part IV. Biochemistry of the organism -- 7. Molecular methods to study transcriptional regulation of Clostridium difficile toxin genes / Ana Antunes and Bruno Dupuy -- 8. Dissecting the cell surface / Robert Fagan and Neil Fairweather -- 9. Human intestinal epithelial response(s) to Clostridium difficile / Nazila V. Jafari, Elaine Allan, and Mona Bajaj-Elliott -- Part V. Genomics -- 10. Comparative genome analysis of Clostridium difficile using DNA microarrays / Richard Stabler, Lisa Dawson, and Brendan Wren -- Part VI. Development of systems for genetic analysis of the organism -- 11. ClosTron-targeted mutagenesis / John T. Heap, Stephen T. Cartman, Sarah A. Kuehne, Clare Cooksley, and Nigel P. Minton -- 12. Methods for gene cloning and targeted mutagenesis / Glen P. Carter, Dena Lyras, Rachael Poon, Pauline M. Howarth, and Julian I. Rood -- 13. Transposon mutagenesis in Clostridium difficile / Haitham A. Hussain, Adam P. Roberts, Rachael Whalan, and Peter Mullany -- Part VII. Animal models of disease -- 14. Refinement of the hamster model of Clostridium difficile disease / Gillian Douce and David Goulding -- 15. Methods for working with the mouse model / Anne Collignon
Control code
658898979
Dimensions
unknown
Extent
1 online resource (x, 241 pages)
Form of item
online
Isbn
9781603273657
Media category
computer
Media MARC source
rdamedia
Media type code
  • c
Other control number
10.1007/978-1-60327-365-7
Other physical details
illustrations.
http://library.link/vocab/ext/overdrive/overdriveId
978-1-60327-364-0
Specific material designation
remote
System control number
(OCoLC)658898979

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