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The Resource Comparative clinical and economic effectiveness of anti-vascular endothelial growth factor agents, principal investigator: Allison Low ; contributing investigators: Devan Kansagara, Michele Freeman, Rochelle Fu, Kavita Bhavsar, Ambar Faridi, Karli Kondo, Robin Paynter

Comparative clinical and economic effectiveness of anti-vascular endothelial growth factor agents, principal investigator: Allison Low ; contributing investigators: Devan Kansagara, Michele Freeman, Rochelle Fu, Kavita Bhavsar, Ambar Faridi, Karli Kondo, Robin Paynter

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Summary
Visual impairment is a common problem among Veterans and results in significant reduction in quality of life. Diseases commonly responsible for substantial losses in visual acuity include neovascular ("wet") age-related macular degeneration (AMD), diabetic macular edema (DME), and central or branch retinal vein occlusion (CRVO or BRVO). While the etiologies of these diseases are complex, all are driven at least in part by vascular endothelial growth factors (VEGFs). This has led to the development of several drugs called anti-VEGF agents designed to block these factors and thus limit their damage to the eye. The most commonly used anti-VEGF agents--aflibercept, bevacizumab, and ranibizumab--have been shown to slow and even reverse the vision loss typically seen in patients with AMD, DME, BRVO, and CRVO. The comparative effectiveness, harms, and costs of these drugs are unclear
Language
eng
Work
Instance
Label
Comparative clinical and economic effectiveness of anti-vascular endothelial growth factor agents
Title
Comparative clinical and economic effectiveness of anti-vascular endothelial growth factor agents
Statement of responsibility
principal investigator: Allison Low ; contributing investigators: Devan Kansagara, Michele Freeman, Rochelle Fu, Kavita Bhavsar, Ambar Faridi, Karli Kondo, Robin Paynter
Creator
Contributor
Author
Issuing body
Subject
Genre
Language
eng
Summary
Visual impairment is a common problem among Veterans and results in significant reduction in quality of life. Diseases commonly responsible for substantial losses in visual acuity include neovascular ("wet") age-related macular degeneration (AMD), diabetic macular edema (DME), and central or branch retinal vein occlusion (CRVO or BRVO). While the etiologies of these diseases are complex, all are driven at least in part by vascular endothelial growth factors (VEGFs). This has led to the development of several drugs called anti-VEGF agents designed to block these factors and thus limit their damage to the eye. The most commonly used anti-VEGF agents--aflibercept, bevacizumab, and ranibizumab--have been shown to slow and even reverse the vision loss typically seen in patients with AMD, DME, BRVO, and CRVO. The comparative effectiveness, harms, and costs of these drugs are unclear
Member of
Cataloging source
NLM
http://library.link/vocab/creatorName
Low, Allison
Government publication
federal national government publication
Illustrations
illustrations
Index
no index present
Literary form
non fiction
Nature of contents
  • dictionaries
  • surveys of literature
NLM call number
WW 270
http://library.link/vocab/relatedWorkOrContributorName
  • United States
  • Portland VA Medical Center
  • Quality Enhancement Research Initiative (U.S.)
Series statement
Evidence-based synthesis program
http://library.link/vocab/subjectName
  • Retinal Diseases
  • Angiogenesis Inhibitors
  • Vascular Endothelial Growth Factors
  • Veterans Health
  • Comparative Effectiveness Research
  • Cost-Benefit Analysis
  • United States
  • United States
Label
Comparative clinical and economic effectiveness of anti-vascular endothelial growth factor agents, principal investigator: Allison Low ; contributing investigators: Devan Kansagara, Michele Freeman, Rochelle Fu, Kavita Bhavsar, Ambar Faridi, Karli Kondo, Robin Paynter
Instantiates
Publication
Note
"January 2017."
Bibliography note
Includes bibliographical references
Carrier category
online resource
Carrier category code
cr
Carrier MARC source
rdacarrier
Content category
text
Content type code
txt
Content type MARC source
rdacontent
Control code
1029858169
Extent
1 online resource (iv, 123 pages)
Form of item
online
Media category
computer
Media MARC source
rdamedia
Media type code
c
Other physical details
illustrations.
Specific material designation
remote
System control number
(OCoLC)1029858169
Label
Comparative clinical and economic effectiveness of anti-vascular endothelial growth factor agents, principal investigator: Allison Low ; contributing investigators: Devan Kansagara, Michele Freeman, Rochelle Fu, Kavita Bhavsar, Ambar Faridi, Karli Kondo, Robin Paynter
Publication
Note
"January 2017."
Bibliography note
Includes bibliographical references
Carrier category
online resource
Carrier category code
cr
Carrier MARC source
rdacarrier
Content category
text
Content type code
txt
Content type MARC source
rdacontent
Control code
1029858169
Extent
1 online resource (iv, 123 pages)
Form of item
online
Media category
computer
Media MARC source
rdamedia
Media type code
c
Other physical details
illustrations.
Specific material designation
remote
System control number
(OCoLC)1029858169

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