Coverart for item
The Resource Computational biology of transcription factor binding, edited by Istvan Ladunga

Computational biology of transcription factor binding, edited by Istvan Ladunga

Label
Computational biology of transcription factor binding
Title
Computational biology of transcription factor binding
Statement of responsibility
edited by Istvan Ladunga
Contributor
Subject
Language
eng
Summary
Through great experimental difficulty, we've witnessed rapid, crucial developments at the intersection of computational biology, experimental technology, and statistics through which the vital process of transcriptional regulation can be further examined. In Computational Biology of Transcription Factor Binding, experts in the field examine the basic principles and provide detailed guidance for the computational analyses and biological interpretations of transcription factor binding, while disclosing critical practical information and caveats that are missing from many research publications. The volume serves not only computational biologists but experimentalists as well, who may want to better understand how to design and execute experiments and to communicate more effectively with computational biologists, computer scientists, and statisticians. Written for the highly successful Methods in Molecular Biology series, this work provides the kind of detailed description and implementation advice that is crucial for getting optimal results in the lab. Authoritative and easy to use, Computational Biology of Transcription Factor Binding guides scientists working in this area and demands not only new experiments but also the re-annotation of existing experimental data and computational predictions leading to important ongoing, major paradigm changes for us all
Member of
Cataloging source
GW5XE
Dewey number
572.80285
Illustrations
illustrations
Index
index present
Language note
English
LC call number
QH324.2
LC item number
.C66 2010
Literary form
non fiction
Nature of contents
  • dictionaries
  • bibliography
NLM call number
QU26.5
NLM item number
C736 2010
http://library.link/vocab/relatedWorkOrContributorName
Ladunga, Istvan
Series statement
  • Springer protocols
  • Methods in molecular biology,
Series volume
674
http://library.link/vocab/subjectName
  • Computational biology
  • Transcription factors
  • Computational Biology
  • Transcription Factors
  • Computational biology
  • Transcription factors
  • Biology
  • Health & Biological Sciences
  • Biology - General
Label
Computational biology of transcription factor binding, edited by Istvan Ladunga
Instantiates
Publication
Bibliography note
Includes bibliographical references and index
Carrier category
online resource
Carrier category code
  • cr
Carrier MARC source
rdacarrier
Color
multicolored
Content category
text
Content type code
  • txt
Content type MARC source
rdacontent
Contents
An overview of the computational analyses and discovery of transcription factor binding sites -- Components and mechanisms of regulation of gene expression -- Regulatory regions in DNA: promoters, enhancers, silencers, and insulators -- Three-dimensional structures of DNA-bound transcriptional regulators -- Identification of promoter regions and regulatory sites -- Motif discovery using expectation maximization and Gibbs' sampling -- Probabilistic approaches to transcription factor binding site prediction -- The motif tool assessment platform (MTAP) for sequence-based transcription factor binding site prediction tools -- Computational analysis of ChIP-seq data -- Probabilistic peak calling and controlling false discovery rate estimations in transcription factor binding site mapping from ChIP-seq -- Sequence analysis of chromatin immunoprecipitation data for transcription factors -- Inferring protein-DNA interaction parameters from SELEX experiments -- Kernel-based identification of regulatory modules -- Identification of transcription factor binding sites derived from transposable element sequences using ChIP-seq -- Target gene identification via nuclear receptor binding site prediction -- Computing chromosome conformation -- Large-scale identification and analysis of C-proteins -- Evolution of cis-regulatory sequences in drosophila -- Regulating the regulators: modulators of transcription factor activity -- Annotating the regulatory genome -- Computational identification of plant transcription factors and the construction of the plant TFDB database -- Practical computational methods for regulatory genomics: a cisGRN-lexicon and cisGRN-browser for gene regulatory networks -- Reconstructing transcriptional regulatory networks using three-way mutual information and bayesian networks -- Computational methods for analyzing dynamic regulatory networks
Control code
670209749
Dimensions
unknown
Extent
1 online resource (xi, 454 pages)
Form of item
online
Isbn
9781607618546
Media category
computer
Media MARC source
rdamedia
Media type code
  • c
Other control number
10.1007/978-1-60761-854-6
Other physical details
illustrations.
http://library.link/vocab/ext/overdrive/overdriveId
978-1-60761-853-9
Specific material designation
remote
System control number
(OCoLC)670209749
Label
Computational biology of transcription factor binding, edited by Istvan Ladunga
Publication
Bibliography note
Includes bibliographical references and index
Carrier category
online resource
Carrier category code
  • cr
Carrier MARC source
rdacarrier
Color
multicolored
Content category
text
Content type code
  • txt
Content type MARC source
rdacontent
Contents
An overview of the computational analyses and discovery of transcription factor binding sites -- Components and mechanisms of regulation of gene expression -- Regulatory regions in DNA: promoters, enhancers, silencers, and insulators -- Three-dimensional structures of DNA-bound transcriptional regulators -- Identification of promoter regions and regulatory sites -- Motif discovery using expectation maximization and Gibbs' sampling -- Probabilistic approaches to transcription factor binding site prediction -- The motif tool assessment platform (MTAP) for sequence-based transcription factor binding site prediction tools -- Computational analysis of ChIP-seq data -- Probabilistic peak calling and controlling false discovery rate estimations in transcription factor binding site mapping from ChIP-seq -- Sequence analysis of chromatin immunoprecipitation data for transcription factors -- Inferring protein-DNA interaction parameters from SELEX experiments -- Kernel-based identification of regulatory modules -- Identification of transcription factor binding sites derived from transposable element sequences using ChIP-seq -- Target gene identification via nuclear receptor binding site prediction -- Computing chromosome conformation -- Large-scale identification and analysis of C-proteins -- Evolution of cis-regulatory sequences in drosophila -- Regulating the regulators: modulators of transcription factor activity -- Annotating the regulatory genome -- Computational identification of plant transcription factors and the construction of the plant TFDB database -- Practical computational methods for regulatory genomics: a cisGRN-lexicon and cisGRN-browser for gene regulatory networks -- Reconstructing transcriptional regulatory networks using three-way mutual information and bayesian networks -- Computational methods for analyzing dynamic regulatory networks
Control code
670209749
Dimensions
unknown
Extent
1 online resource (xi, 454 pages)
Form of item
online
Isbn
9781607618546
Media category
computer
Media MARC source
rdamedia
Media type code
  • c
Other control number
10.1007/978-1-60761-854-6
Other physical details
illustrations.
http://library.link/vocab/ext/overdrive/overdriveId
978-1-60761-853-9
Specific material designation
remote
System control number
(OCoLC)670209749

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