The Resource Development of a biosensor for the detection of Helicobacter hepaticus utilizing multi-functioning immobilization platforms, by Jasenka Memisevic, (electronic resource)

Development of a biosensor for the detection of Helicobacter hepaticus utilizing multi-functioning immobilization platforms, by Jasenka Memisevic, (electronic resource)

Label
Development of a biosensor for the detection of Helicobacter hepaticus utilizing multi-functioning immobilization platforms
Title
Development of a biosensor for the detection of Helicobacter hepaticus utilizing multi-functioning immobilization platforms
Statement of responsibility
by Jasenka Memisevic
Creator
Contributor
Thesis advisor
Subject
Genre
Language
eng
Summary
Optical biosensor development is a process involving the careful selection of the material for the immobilization platform, design of the detection mechanism and integration with optical and electronic equipment. The ability of biosensor to outperform the currently available technology, while reducing the cost and providing ease of use is of utmost importance. This work describes the research performed in effort to develop a high surface area material for biosensor immobilization, which improves the biosensor's function with the incorporation of fluorescence. Two silica-based nanoporous materials were evaluated, the nanoporous organosilicate (NPO) and fluorescent electrospun sol-gelnano/microfibers. The biosensor was also developed utilizing the immunosensing technique in a sandwich-based assay. The fluorescence based optical biosensor involves the use of organic fluorophores along with colloidal gold nanoparticles. When used as reporter molecules, the gold nanoparticles quench fluorescence of the fluorophores in the biosensor immobilization platform, thus signaling the presence of analytes. The results indicate that utilizing materials with high surface area to volume ratios, with embedded fluorescence, and the sandwich-based immunoassay provides a highly specific biosensor with a low level of detection
Cataloging source
MUU
http://library.link/vocab/creatorDate
1983-
http://library.link/vocab/creatorName
Memisevic, Jasenka
Degree
Ph. D.
Dissertation year
2010.
Granting institution
University of Missouri--Columbia
Illustrations
illustrations
Index
no index present
Literary form
non fiction
Nature of contents
  • dictionaries
  • bibliography
  • theses
http://library.link/vocab/relatedWorkOrContributorName
Grant, Sheila Ann
http://library.link/vocab/subjectName
  • Helicobacter
  • Gram-negative bacteria
  • Nanoparticles
  • Biosensors
  • Immobilized cells
Target audience
specialized
Label
Development of a biosensor for the detection of Helicobacter hepaticus utilizing multi-functioning immobilization platforms, by Jasenka Memisevic, (electronic resource)
Instantiates
Publication
Note
  • Title from PDF of title page (University of Missouri--Columbia, viewed on August 23, 2010)
  • The entire thesis text is included in the research.pdf file; the official abstract appears in the short.pdf file; a non-technical public abstract appears in the public.pdf file
  • Dissertation advisor: Dr. Sheila A. Grant
  • Vita
Bibliography note
Includes bibliographical references
Carrier category
online resource
Carrier category code
cr
Carrier MARC source
rdacarrier
Content category
text
Content type code
txt
Content type MARC source
rdacontent
Control code
671404586
Extent
1 online resource (xiv, 177 pages)
Form of item
online
Media category
computer
Media MARC source
rdamedia
Media type code
c
Other physical details
illustrations (some color).
Specific material designation
remote
System control number
(OCoLC)671404586
Label
Development of a biosensor for the detection of Helicobacter hepaticus utilizing multi-functioning immobilization platforms, by Jasenka Memisevic, (electronic resource)
Publication
Note
  • Title from PDF of title page (University of Missouri--Columbia, viewed on August 23, 2010)
  • The entire thesis text is included in the research.pdf file; the official abstract appears in the short.pdf file; a non-technical public abstract appears in the public.pdf file
  • Dissertation advisor: Dr. Sheila A. Grant
  • Vita
Bibliography note
Includes bibliographical references
Carrier category
online resource
Carrier category code
cr
Carrier MARC source
rdacarrier
Content category
text
Content type code
txt
Content type MARC source
rdacontent
Control code
671404586
Extent
1 online resource (xiv, 177 pages)
Form of item
online
Media category
computer
Media MARC source
rdamedia
Media type code
c
Other physical details
illustrations (some color).
Specific material designation
remote
System control number
(OCoLC)671404586

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