Coverart for item
The Resource Development of a human immunodeficiency virus (HIV-1) biosensor utilizing liquid core waveguides, by Rosalynn M. Smith, (electronic resource)

Development of a human immunodeficiency virus (HIV-1) biosensor utilizing liquid core waveguides, by Rosalynn M. Smith, (electronic resource)

Label
Development of a human immunodeficiency virus (HIV-1) biosensor utilizing liquid core waveguides
Title
Development of a human immunodeficiency virus (HIV-1) biosensor utilizing liquid core waveguides
Statement of responsibility
by Rosalynn M. Smith
Creator
Contributor
Thesis advisor
Subject
Genre
Language
eng
Summary
Millions of individuals are diagnosed each year with Human Immunodeficiency Virus Type 1. Each day more individuals are receiving antiretroviral medication to suppress the amount of virus in their blood, and diminish viral replication. In addition to worldwide initiatives to distribute antiretroviral medications, research is underway to design detection systems that will rapidly report the amount of viral load of individuals in developed and undeveloped areas for a low price, with little maintenance, and that require far less lab space. A novel biosensor for dual detection of viral particles, utilizing Förster Resonance Energy Transfer (FRET) is reported. Soluble CD4 (sCD4) and a coreceptor such as gp120 monoclonal antibody (gp120 mAb) or anti-gp120 RNA aptamer are utilized as primary and coreceptors for detection of HIV-1 viral particles. Fluorescent molecules conjugated to sCD4, gp120 mAb, or RNA aptamer act as energy donors or acceptors during the FRET process. Results verify the ability to detect recombinant gp120 and HIV- 1 pseudoviral particles utilizing sCD4 and gp120 mAb. In this study dye molecules and quantum dots are conjugated to receptors to quantify the amount of HIV-1 in solution
Cataloging source
MUU
http://library.link/vocab/creatorName
Smith, Rosalynn M
Degree
Ph. D.
Dissertation year
2007.
Granting institution
University of Missouri-Columbia
Illustrations
illustrations
Index
no index present
Literary form
non fiction
Nature of contents
  • dictionaries
  • bibliography
  • theses
http://library.link/vocab/relatedWorkOrContributorName
  • Gangopadhyay, Shubhra
  • Grant, Sheila Ann
http://library.link/vocab/subjectName
  • Biosensors
  • HIV (Viruses)
  • Energy transfer
Target audience
specialized
Label
Development of a human immunodeficiency virus (HIV-1) biosensor utilizing liquid core waveguides, by Rosalynn M. Smith, (electronic resource)
Instantiates
Publication
Note
  • The entire dissertation/thesis text is included in the research.pdf file; the official abstract appears in the short.pdf file (which also appears in the research.pdf); a non-technical general description, or public abstract, appears in the public.pdf file
  • Title from title screen of research.pdf file (viewed on October 18, 2007)
  • Vita
Bibliography note
Includes bibliographical references
Carrier category
online resource
Carrier category code
  • cr
Carrier MARC source
rdacarrier
Color
mixed
Content category
text
Content type code
  • txt
Content type MARC source
rdacontent
Control code
174958795
Dimensions
unknown
Form of item
electronic
Governing access note
Access is limited to the campus of the University of Missouri-Columbia
Media category
computer
Media MARC source
rdamedia
Media type code
  • c
Specific material designation
remote
System control number
(OCoLC)174958795
System details
Mode of access: World Wide Web
Terms governing use
Access is limited to the campus of the University of Missouri-Columbia.
Label
Development of a human immunodeficiency virus (HIV-1) biosensor utilizing liquid core waveguides, by Rosalynn M. Smith, (electronic resource)
Publication
Note
  • The entire dissertation/thesis text is included in the research.pdf file; the official abstract appears in the short.pdf file (which also appears in the research.pdf); a non-technical general description, or public abstract, appears in the public.pdf file
  • Title from title screen of research.pdf file (viewed on October 18, 2007)
  • Vita
Bibliography note
Includes bibliographical references
Carrier category
online resource
Carrier category code
  • cr
Carrier MARC source
rdacarrier
Color
mixed
Content category
text
Content type code
  • txt
Content type MARC source
rdacontent
Control code
174958795
Dimensions
unknown
Form of item
electronic
Governing access note
Access is limited to the campus of the University of Missouri-Columbia
Media category
computer
Media MARC source
rdamedia
Media type code
  • c
Specific material designation
remote
System control number
(OCoLC)174958795
System details
Mode of access: World Wide Web
Terms governing use
Access is limited to the campus of the University of Missouri-Columbia.

Library Locations

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      38.944491 -92.326012
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