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The Resource Development of electrospun synthetic bioabsorbable fibers for a novel bionanocomposite hernia repair material, by J. Todd Vassalli, (electronic resource)

Development of electrospun synthetic bioabsorbable fibers for a novel bionanocomposite hernia repair material, by J. Todd Vassalli, (electronic resource)

Creator
Contributor
Summary
In order to create a more durable and biocompatible hernia repair mesh, a novel bionanocomposite material based on the crosslinking of bioabsorbable polymer fibers to decellularized porcine diaphragm tissue is proposed. The first step in creating this bionanocomposite material is to develop a method to produce and functionalize bioabsorbable polymer fibers. Electrospinning was chosen for its effectiveness and cost efficiency in producing polymer fibers in the sub-micron range. For this project, an electrospinning solution consisting of the degradable polymer polycaprolactone is treated with the aminolyzing agent ethylenediamine in order to add amine groups to the resulting electrospun fibers. Amine-group functionalization is measured using FT-IR scans of electrospun test samples. The degree of sample functionalization is measured as a numeric area of the respective amine peaks from the resulting FT-IR absorbance graphs. Current research findings indicate that it is possible to produce functionalized polycaprolactone fibers in the sub-micron range based on this experimental method
Language
eng
Work
Publication
Extent
1 online resource (viii, 93 pages)
Note
  • The entire thesis text is included in the research.pdf file; the official abstract appears in the short.pdf file; a non-technical public abstract appears in the public.pdf file
  • Title from PDF of title page (University of Missouri--Columbia, viewed on October 6, 2009)
  • Thesis advisor: Dr. Sheila Grant,
Instance
Label
Development of electrospun synthetic bioabsorbable fibers for a novel bionanocomposite hernia repair material
Title
Development of electrospun synthetic bioabsorbable fibers for a novel bionanocomposite hernia repair material
Statement of responsibility
by J. Todd Vassalli
Creator
Contributor
Thesis advisor
Subject
Genre
Language
eng
Summary
In order to create a more durable and biocompatible hernia repair mesh, a novel bionanocomposite material based on the crosslinking of bioabsorbable polymer fibers to decellularized porcine diaphragm tissue is proposed. The first step in creating this bionanocomposite material is to develop a method to produce and functionalize bioabsorbable polymer fibers. Electrospinning was chosen for its effectiveness and cost efficiency in producing polymer fibers in the sub-micron range. For this project, an electrospinning solution consisting of the degradable polymer polycaprolactone is treated with the aminolyzing agent ethylenediamine in order to add amine groups to the resulting electrospun fibers. Amine-group functionalization is measured using FT-IR scans of electrospun test samples. The degree of sample functionalization is measured as a numeric area of the respective amine peaks from the resulting FT-IR absorbance graphs. Current research findings indicate that it is possible to produce functionalized polycaprolactone fibers in the sub-micron range based on this experimental method
Cataloging source
MUU
http://library.link/vocab/creatorName
Vassalli, J. Todd
Degree
M.S.
Dissertation year
2008.
Granting institution
University of Missouri--Columbia
Illustrations
illustrations
Index
no index present
Literary form
non fiction
Nature of contents
  • dictionaries
  • bibliography
  • theses
http://library.link/vocab/relatedWorkOrContributorName
Grant, Sheila Ann
http://library.link/vocab/subjectName
  • Hernia
  • Electrospinning
  • Biomedical materials
Target audience
specialized
Label
Development of electrospun synthetic bioabsorbable fibers for a novel bionanocomposite hernia repair material, by J. Todd Vassalli, (electronic resource)
Instantiates
Publication
Note
  • The entire thesis text is included in the research.pdf file; the official abstract appears in the short.pdf file; a non-technical public abstract appears in the public.pdf file
  • Title from PDF of title page (University of Missouri--Columbia, viewed on October 6, 2009)
  • Thesis advisor: Dr. Sheila Grant,
Bibliography note
Includes bibliographical references
Carrier category
online resource
Carrier category code
  • cr
Carrier MARC source
rdacarrier
Content category
text
Content type code
  • txt
Content type MARC source
rdacontent
Control code
449946599
Extent
1 online resource (viii, 93 pages)
Form of item
electronic
Media category
computer
Media MARC source
rdamedia
Media type code
  • c
Other physical details
illustrations (some color).
Specific material designation
remote
System control number
(OCoLC)449946599
Label
Development of electrospun synthetic bioabsorbable fibers for a novel bionanocomposite hernia repair material, by J. Todd Vassalli, (electronic resource)
Publication
Note
  • The entire thesis text is included in the research.pdf file; the official abstract appears in the short.pdf file; a non-technical public abstract appears in the public.pdf file
  • Title from PDF of title page (University of Missouri--Columbia, viewed on October 6, 2009)
  • Thesis advisor: Dr. Sheila Grant,
Bibliography note
Includes bibliographical references
Carrier category
online resource
Carrier category code
  • cr
Carrier MARC source
rdacarrier
Content category
text
Content type code
  • txt
Content type MARC source
rdacontent
Control code
449946599
Extent
1 online resource (viii, 93 pages)
Form of item
electronic
Media category
computer
Media MARC source
rdamedia
Media type code
  • c
Other physical details
illustrations (some color).
Specific material designation
remote
System control number
(OCoLC)449946599

Subject

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