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The Resource Directed evolution library creation : methods and protocols, edited by Elizabeth M.J. Gillam, Janine N. Copp, David F. Ackerley

Directed evolution library creation : methods and protocols, edited by Elizabeth M.J. Gillam, Janine N. Copp, David F. Ackerley

Label
Directed evolution library creation : methods and protocols
Title
Directed evolution library creation
Title remainder
methods and protocols
Statement of responsibility
edited by Elizabeth M.J. Gillam, Janine N. Copp, David F. Ackerley
Contributor
Copyright holder
Editor
Subject
Genre
Language
eng
Summary
Directed Evolution Library Creation: Methods and Protocols, Second Edition presents user-friendly protocols for both proven strategies and cutting-edge approaches for the creation of mutant gene libraries for directed evolution. As well as experimental methods, information on current computational approaches is provided in a user-friendly format that will allow researchers to make informed choices without needing to comprehend the full technical details of each algorithm. Directed evolution has become a fundamental approach for engineering proteins to enhance activity and explore structure-function relationships, and has supported the rapid development of the field of synthetic biology over the last decade. Divided into three convenient sections, topics include point mutagenesis strategies, recombinatorial methods wherein genetic diversity is sourced from multiple parental genes that are combined via either homology-dependent or -independent techniques and a variety of computational methods to guide the design and analysis of mutant libraries. Written in the successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible protocols and notes on troubleshooting and avoiding known pitfalls. Authoritative and easily accessible, Directed Evolution Library Creation: Methods and Protocols, Second Edition will serve as a reliable manual for both novice and experienced protein engineers and synthetic biologists and will enable further technical innovation and the exploitation of directed evolution for a deeper understanding of protein design and function
Member of
Cataloging source
UKMGB
Dewey number
572.838
Illustrations
illustrations
Index
index present
Literary form
non fiction
Nature of contents
bibliography
http://library.link/vocab/relatedWorkOrContributorName
  • Gillam, Elizabeth M. J.
  • Copp, Janine N.
  • Ackerley, David F.
  • Springer Science+Business Media
Series statement
  • Methods in molecular biology,
  • Springer protocols,
Series volume
1179
http://library.link/vocab/subjectName
  • Gene libraries
  • Genetic engineering
  • Molecular evolution
  • Microbial mutation
  • Combinatorial chemistry
  • Genetic recombination
  • Evolutionary genetics
  • Gene libraries
  • Mutagenesis
  • Directed Molecular Evolution
  • Combinatorial Chemistry Techniques
  • DNA, Recombinant
  • Gene Library
  • Genomic Library
  • Mutagenesis
Label
Directed evolution library creation : methods and protocols, edited by Elizabeth M.J. Gillam, Janine N. Copp, David F. Ackerley
Instantiates
Publication
Bibliography note
Includes bibliographical references and index
Carrier category
volume
Carrier category code
  • nc
Carrier MARC source
rdacarrier
Content category
text
Content type code
  • txt
Content type MARC source
rdacontent
Contents
Point mutagenesis -- Recombinatorial methods -- Structure-guided methods and computational tools for the design and analysis of mutant libraries
Control code
885447740
Dimensions
26 cm
Edition
Second edition.
Extent
xi, 369 pages
Isbn
9781493910526
Lccn
2014943737
Media category
unmediated
Media MARC source
rdamedia
Media type code
  • n
Other physical details
illustrations (some color)
System control number
(OCoLC)885447740
Label
Directed evolution library creation : methods and protocols, edited by Elizabeth M.J. Gillam, Janine N. Copp, David F. Ackerley
Publication
Bibliography note
Includes bibliographical references and index
Carrier category
volume
Carrier category code
  • nc
Carrier MARC source
rdacarrier
Content category
text
Content type code
  • txt
Content type MARC source
rdacontent
Contents
Point mutagenesis -- Recombinatorial methods -- Structure-guided methods and computational tools for the design and analysis of mutant libraries
Control code
885447740
Dimensions
26 cm
Edition
Second edition.
Extent
xi, 369 pages
Isbn
9781493910526
Lccn
2014943737
Media category
unmediated
Media MARC source
rdamedia
Media type code
  • n
Other physical details
illustrations (some color)
System control number
(OCoLC)885447740

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