Coverart for item
The Resource Drug repurposing and repositioning : workshop summary, Sarah H. Beachy, Samuel G. Johnson, Steve Olson, and Adam C. Berger, rapporteurs ; Roundtable on Translating Genomic-Based Research for Health, Board on Health Sciences Policy, Institute of Medicine of the National Academies

Drug repurposing and repositioning : workshop summary, Sarah H. Beachy, Samuel G. Johnson, Steve Olson, and Adam C. Berger, rapporteurs ; Roundtable on Translating Genomic-Based Research for Health, Board on Health Sciences Policy, Institute of Medicine of the National Academies

Label
Drug repurposing and repositioning : workshop summary
Title
Drug repurposing and repositioning
Title remainder
workshop summary
Statement of responsibility
Sarah H. Beachy, Samuel G. Johnson, Steve Olson, and Adam C. Berger, rapporteurs ; Roundtable on Translating Genomic-Based Research for Health, Board on Health Sciences Policy, Institute of Medicine of the National Academies
Creator
Contributor
Issuing body
Subject
Genre
Language
eng
Summary
"Drug development can be time-consuming and expensive. Recent estimates suggest that, on average, it takes 10 years and at least $1 billion to bring a drug to market. Given the time and expense of developing drugs de novo, pharmaceutical companies have become increasingly interested in finding new uses for existing drugs--a process referred to as drug repurposing or repositioning. Historically, drug repurposing has been largely an unintentional, serendipitous process that took place when a drug was found to have an offtarget effect or a previously unrecognized on-target effect that could be used for identifying a new indication. Perhaps the most recognizable example of such a successful repositioning effort is sildenafil. Originally developed as an anti-hypertensive, sildenafil, marketed as Viagra and under other trade names, has been repurposed for the treatment of erectile dysfunction and pulmonary arterial hypertension. Viagra generated more than $2 billion worldwide in 2012 and has recently been studied for the treatment of heart failure. Given the widespread interest in drug repurposing, the Roundtable on Translating Genomic-Based Research for Health of the Institute of Medicine hosted a workshop on June 24, 2013, in Washington, DC, to assess the current landscape of drug repurposing activities in industry, academia, and government. Stakeholders, including government officials, pharmaceutical company representatives, academic researchers, regulators, funders, and patients, were invited to present their perspectives and to participate in workshop discussions. Drug Repurposing and Repositioning is the summary of that workshop. This report examines enabling tools and technology for drug repurposing; evaluates the business models and economic incentives for pursuing a repurposing approach; and discusses how genomic and genetic research could be positioned to better enable a drug repurposing paradigm"--Publisher's description
Member of
Cataloging source
N$T
Dewey number
615.1/9
Illustrations
illustrations
Index
no index present
LC call number
RM301.25
LC item number
.D78 2013eb
Literary form
non fiction
http://bibfra.me/vocab/lite/meetingDate
2013
http://bibfra.me/vocab/lite/meetingName
Drug Repurposing and Repositioning (Workshop)
Nature of contents
  • dictionaries
  • bibliography
http://bibfra.me/vocab/relation/rapporteur
  • VeUaQOu8yVk
  • iOqIckmEKMY
  • 77ZvP6No5U8
  • jETwvWfdzMU
http://library.link/vocab/relatedWorkOrContributorDate
1956-
http://library.link/vocab/relatedWorkOrContributorName
  • Beachy, Sarah H.
  • Johnson, Samuel G.
  • Olson, Steve
  • Berger, Adam C.
  • Institute of Medicine (U.S.)
http://library.link/vocab/subjectName
  • Drug development
  • Drugs
  • Pharmaceutical industry
  • Drug Repositioning
  • Drug Discovery
  • Pharmaceutical Preparations
  • MEDICAL
  • Drug development
  • Drugs
  • Pharmaceutical industry
  • United States
Label
Drug repurposing and repositioning : workshop summary, Sarah H. Beachy, Samuel G. Johnson, Steve Olson, and Adam C. Berger, rapporteurs ; Roundtable on Translating Genomic-Based Research for Health, Board on Health Sciences Policy, Institute of Medicine of the National Academies
Instantiates
Publication
Copyright
Antecedent source
unknown
Bibliography note
Includes bibliographical references (pages 57-63)
Carrier category
online resource
Carrier category code
  • cr
Carrier MARC source
rdacarrier
Color
multicolored
Content category
text
Content type code
  • txt
Content type MARC source
rdacontent
Contents
Introduction and themes of the workshop -- The state of the science -- Enabling tools and technology -- Value propositions for drug repurposing -- Policy approaches and legal framework -- Increasing the efficiency and success of repurposing
Control code
893439616
Dimensions
unknown
Extent
1 online resource (xxii, 96 pages)
File format
unknown
Form of item
online
Isbn
9780309302050
Lccn
2014501917
Level of compression
unknown
Media category
computer
Media MARC source
rdamedia
Media type code
  • c
Other physical details
illustrations
Quality assurance targets
not applicable
Reformatting quality
unknown
Sound
unknown sound
Specific material designation
remote
System control number
(OCoLC)893439616
Label
Drug repurposing and repositioning : workshop summary, Sarah H. Beachy, Samuel G. Johnson, Steve Olson, and Adam C. Berger, rapporteurs ; Roundtable on Translating Genomic-Based Research for Health, Board on Health Sciences Policy, Institute of Medicine of the National Academies
Publication
Copyright
Antecedent source
unknown
Bibliography note
Includes bibliographical references (pages 57-63)
Carrier category
online resource
Carrier category code
  • cr
Carrier MARC source
rdacarrier
Color
multicolored
Content category
text
Content type code
  • txt
Content type MARC source
rdacontent
Contents
Introduction and themes of the workshop -- The state of the science -- Enabling tools and technology -- Value propositions for drug repurposing -- Policy approaches and legal framework -- Increasing the efficiency and success of repurposing
Control code
893439616
Dimensions
unknown
Extent
1 online resource (xxii, 96 pages)
File format
unknown
Form of item
online
Isbn
9780309302050
Lccn
2014501917
Level of compression
unknown
Media category
computer
Media MARC source
rdamedia
Media type code
  • c
Other physical details
illustrations
Quality assurance targets
not applicable
Reformatting quality
unknown
Sound
unknown sound
Specific material designation
remote
System control number
(OCoLC)893439616

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