Borrow it
- Ellis Library
- Engineering Library & Technology Commons
- Fisher Delta Research Center
- Geological Sciences Library
- J. Otto Lottes Health Sciences Library
- Journalism Library
- Mathematical Sciences Library
- University Archives
- University Archives McAlester Annex
- University of Missouri Libraries Depository
- Zalk Veterinary Medical Library
The Resource Electrospinning collagen and hyaluronic acid nanofiber meshes
Electrospinning collagen and hyaluronic acid nanofiber meshes
Resource Information
The item Electrospinning collagen and hyaluronic acid nanofiber meshes represents a specific, individual, material embodiment of a distinct intellectual or artistic creation found in University of Missouri Libraries.This item is available to borrow from all library branches.
Resource Information
The item Electrospinning collagen and hyaluronic acid nanofiber meshes represents a specific, individual, material embodiment of a distinct intellectual or artistic creation found in University of Missouri Libraries.
This item is available to borrow from all library branches.
- Summary
- Osteoporosis is a worldwide burden affecting over 200 million people. There are many risk factors associated with osteoporosis, but they all lead to decreased bone strength and an increased chance of bone fracture. The field of tissue engineering could be used to create bone substitute materials that can increase bone strength or promote new bone growth. Collagen and hyaluronic acid (HA) are particularly interesting due to their roles in the extracellular matrix (ECM) of humans and their ability to stimulate bone forming cells. These materials can be processed into nanofiber scaffolds using a technique called electrospinning; a process that applies high voltage to a polymer solution to draw out nanofibers that are collected on a ground plate. An electrospinning solution of collagen/HA was synthesized, and the electrospinning apparatus was adjusted to generate uniform nanofiber meshes with consistent nanofiber diameter. The meshes were then crosslinked to render them insoluble in aqueous solutions, and gold nanoparticles (AuNPs) were conjugated to the surface to promote cellular in-growth. Scanning electron microscope (SEM) was utilized to image the nanofiber mesh surface and electron dispersive spectroscopy (EDS) was used to quantify the charged particles on the mesh as gold. Fourier transform infrared spectroscopy (FT-IR) was used to find the absorption spectrum and bonding changes after each step. A WST-1 assay was also performed to determine the potential biocompatibility. The results show that it was possible to develop scaffolds that were insoluble in aqueous solutions and promoted cellular attachment and proliferation. In conclusion, nanofiber meshes made from collagen/HA could be utilized as a tissue engineered scaffold to promote bone growth
- Language
- eng
- Extent
- 1 online resource (viii, 82 pages)
- Note
- Advisor: Sheila Ann Grant
- Label
- Electrospinning collagen and hyaluronic acid nanofiber meshes
- Title
- Electrospinning collagen and hyaluronic acid nanofiber meshes
- Language
- eng
- Summary
- Osteoporosis is a worldwide burden affecting over 200 million people. There are many risk factors associated with osteoporosis, but they all lead to decreased bone strength and an increased chance of bone fracture. The field of tissue engineering could be used to create bone substitute materials that can increase bone strength or promote new bone growth. Collagen and hyaluronic acid (HA) are particularly interesting due to their roles in the extracellular matrix (ECM) of humans and their ability to stimulate bone forming cells. These materials can be processed into nanofiber scaffolds using a technique called electrospinning; a process that applies high voltage to a polymer solution to draw out nanofibers that are collected on a ground plate. An electrospinning solution of collagen/HA was synthesized, and the electrospinning apparatus was adjusted to generate uniform nanofiber meshes with consistent nanofiber diameter. The meshes were then crosslinked to render them insoluble in aqueous solutions, and gold nanoparticles (AuNPs) were conjugated to the surface to promote cellular in-growth. Scanning electron microscope (SEM) was utilized to image the nanofiber mesh surface and electron dispersive spectroscopy (EDS) was used to quantify the charged particles on the mesh as gold. Fourier transform infrared spectroscopy (FT-IR) was used to find the absorption spectrum and bonding changes after each step. A WST-1 assay was also performed to determine the potential biocompatibility. The results show that it was possible to develop scaffolds that were insoluble in aqueous solutions and promoted cellular attachment and proliferation. In conclusion, nanofiber meshes made from collagen/HA could be utilized as a tissue engineered scaffold to promote bone growth
- Cataloging source
- MUU
- http://library.link/vocab/creatorName
- Fischer, Rachael
- Degree
- M.S.
- Dissertation note
- Thesis
- Dissertation year
- 2011.
- Government publication
- government publication of a state province territory dependency etc
- Granting institution
- University of Missouri--Columbia,
- Index
- no index present
- Literary form
- non fiction
- Nature of contents
- dictionaries
- Label
- Electrospinning collagen and hyaluronic acid nanofiber meshes
- Note
- Advisor: Sheila Ann Grant
- Carrier category
- online resource
- Carrier category code
-
- cr
- Carrier MARC source
- rdacarrier.
- Content category
- text
- Content type code
-
- txt
- Content type MARC source
- rdacontent.
- Control code
- 876749964
- Extent
- 1 online resource (viii, 82 pages)
- Form of item
- online
- Media category
- computer
- Media MARC source
- rdamedia.
- Media type code
-
- c
- Specific material designation
- remote
- System control number
- (OCoLC)876749964
- Label
- Electrospinning collagen and hyaluronic acid nanofiber meshes
- Note
- Advisor: Sheila Ann Grant
- Carrier category
- online resource
- Carrier category code
-
- cr
- Carrier MARC source
- rdacarrier.
- Content category
- text
- Content type code
-
- txt
- Content type MARC source
- rdacontent.
- Control code
- 876749964
- Extent
- 1 online resource (viii, 82 pages)
- Form of item
- online
- Media category
- computer
- Media MARC source
- rdamedia.
- Media type code
-
- c
- Specific material designation
- remote
- System control number
- (OCoLC)876749964
Library Locations
-
-
Engineering Library & Technology CommonsBorrow itW2001 Lafferre Hall, Columbia, MO, 65211, US38.946102 -92.330125
-
Fisher Delta Research CenterBorrow it2-64 Agricultural Bldg, Columbia, MO, 65201, US38.958397 -92.303491
-
Geological Sciences LibraryBorrow it201 Geological Sciences, Columbia, MO, 65211, US38.947375 -92.329062
-
J. Otto Lottes Health Sciences LibraryBorrow it1 Hospital Dr, Columbia, MO, 65201, US38.939544 -92.328377
-
Journalism LibraryBorrow it102 Reynolds Jrnlism Institute, Columbia, MO, 65211, US38.947290 -92.328025
-
Mathematical Sciences LibraryBorrow it104 Ellis Library, Columbia, MO, 65201, US38.944377 -92.326537
-
University ArchivesBorrow itColumbia, MO, 65201, US
-
University Archives McAlester AnnexBorrow it703 Lewis Hall, Columbia, MO, 65211, US38.934630 -92.342290
-
University of Missouri Libraries DepositoryBorrow it2908 Lemone Blvd, Columbia, MO, 65211, US38.919360 -92.291620
-
Zalk Veterinary Medical LibraryBorrow itVeterinary Medicine West, Columbia, MO, 65211, US38.941099 -92.317911
Library Links
Embed
Settings
Select options that apply then copy and paste the RDF/HTML data fragment to include in your application
Embed this data in a secure (HTTPS) page:
Layout options:
Include data citation:
<div class="citation" vocab="http://schema.org/"><i class="fa fa-external-link-square fa-fw"></i> Data from <span resource="http://link.library.missouri.edu/portal/Electrospinning-collagen-and-hyaluronic-acid/1L4qxpkbRrg/" typeof="Book http://bibfra.me/vocab/lite/Item"><span property="name http://bibfra.me/vocab/lite/label"><a href="http://link.library.missouri.edu/portal/Electrospinning-collagen-and-hyaluronic-acid/1L4qxpkbRrg/">Electrospinning collagen and hyaluronic acid nanofiber meshes</a></span> - <span property="potentialAction" typeOf="OrganizeAction"><span property="agent" typeof="LibrarySystem http://library.link/vocab/LibrarySystem" resource="http://link.library.missouri.edu/"><span property="name http://bibfra.me/vocab/lite/label"><a property="url" href="http://link.library.missouri.edu/">University of Missouri Libraries</a></span></span></span></span></div>
Note: Adjust the width and height settings defined in the RDF/HTML code fragment to best match your requirements
Preview
Cite Data - Experimental
Data Citation of the Item Electrospinning collagen and hyaluronic acid nanofiber meshes
Copy and paste the following RDF/HTML data fragment to cite this resource
<div class="citation" vocab="http://schema.org/"><i class="fa fa-external-link-square fa-fw"></i> Data from <span resource="http://link.library.missouri.edu/portal/Electrospinning-collagen-and-hyaluronic-acid/1L4qxpkbRrg/" typeof="Book http://bibfra.me/vocab/lite/Item"><span property="name http://bibfra.me/vocab/lite/label"><a href="http://link.library.missouri.edu/portal/Electrospinning-collagen-and-hyaluronic-acid/1L4qxpkbRrg/">Electrospinning collagen and hyaluronic acid nanofiber meshes</a></span> - <span property="potentialAction" typeOf="OrganizeAction"><span property="agent" typeof="LibrarySystem http://library.link/vocab/LibrarySystem" resource="http://link.library.missouri.edu/"><span property="name http://bibfra.me/vocab/lite/label"><a property="url" href="http://link.library.missouri.edu/">University of Missouri Libraries</a></span></span></span></span></div>