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The Resource Essential concepts in toxicogenomics, edited by Donna L. Mendrick, William B. Mattes

Essential concepts in toxicogenomics, edited by Donna L. Mendrick, William B. Mattes

Contributor
Summary
The field of toxicogenomics has been growing quickly, yet with rapid growth comes the need to periodically reflect on the nature of the field. Essential Concepts in Toxicogenomics collects reviews, opinion pieces and case studies from the leading experts in this dynamic field with a focus on its application to pharmaceuticals. Topics covered include issues that affect the quality of toxicogenomics experiments, statistical approaches to their data analysis, the use of such data to build toxicogenomic models, and the utilization of genomics to identify biomarkers within the preclinical and clinical arenas. Although not in the standard Methods in Molecular Biology series format, this volume retains the practicality and usefulness of the highly successful series. Informative and cutting-edge, Essential Concepts in Toxicogenomics is an ideal resource for pharmaceutical companies, chemical manufacturers, toxicologists, and all who must keep up-to-date on progress in this vital and important field
Language
eng
Work
Publication
Extent
1 online resource (xi, 277 pages, 8 pages of plates)
Contents
  • Toxicogenomics and classical toxicology, how to improve prediction and mechanistic understanding of human toxicity / Donna L. Mendrick
  • Use of traditional endpoints and gene dysregulation to understand mechanisms of toxicity / Wayne R. Buck, Jeffrey F. Waring, Eric A. Blomme
  • Quality control of microarray assays for toxicogenomic and in vitro diagnostic applications / Karol L. Thompson and Joseph Hackett
  • Role of statistics in toxicogenomics / Michael Elashoff
  • Predictive toxicogenomics in preclinical discovery / Scott A. Barros and Rory B. Martin
  • In vivo predictive toxicogenomics / Mark W. Porter
  • Bioinformatics, databasing and gene annotation / Lyle D. Burgoon and Timothy R. Zacharewski
  • Microarray probe mapping and annotation in cross
  • species comparative toxicogenomics / John N Calley, William B Mattes, Timothy P. Ryan
  • Toxicogenomics in biomarker discovery
  • Marc F. DeCristofaro, Kellye K. Daniels
  • From pharmacogenomics to translational biomarkers / Donna L. Mendrick
  • Public consortium efforts in toxicogenomics / William B. Mattes
  • Applications of toxicogenomics to nonclinical drug development / Frank D. Sistare, Joseph J. DeGeorge
Isbn
9781603270489
Instance
Label
Essential concepts in toxicogenomics
Title
Essential concepts in toxicogenomics
Statement of responsibility
edited by Donna L. Mendrick, William B. Mattes
Contributor
Subject
Language
eng
Summary
The field of toxicogenomics has been growing quickly, yet with rapid growth comes the need to periodically reflect on the nature of the field. Essential Concepts in Toxicogenomics collects reviews, opinion pieces and case studies from the leading experts in this dynamic field with a focus on its application to pharmaceuticals. Topics covered include issues that affect the quality of toxicogenomics experiments, statistical approaches to their data analysis, the use of such data to build toxicogenomic models, and the utilization of genomics to identify biomarkers within the preclinical and clinical arenas. Although not in the standard Methods in Molecular Biology series format, this volume retains the practicality and usefulness of the highly successful series. Informative and cutting-edge, Essential Concepts in Toxicogenomics is an ideal resource for pharmaceutical companies, chemical manufacturers, toxicologists, and all who must keep up-to-date on progress in this vital and important field
Member of
Cataloging source
VVL
Dewey number
616.042
Illustrations
  • illustrations
  • plates
Index
index present
Language note
English
LC call number
RA1224.3
Literary form
non fiction
Nature of contents
  • dictionaries
  • bibliography
NLM call number
  • W1
  • QV 38
NLM item number
  • ME9616J v.460 2008
  • E773 2008
http://library.link/vocab/relatedWorkOrContributorName
  • Mendrick, Donna L
  • Mattes, William B
Series statement
Methods in molecular biology
Series volume
v. 460
http://library.link/vocab/subjectName
  • Genetic toxicology
  • Genomics
  • Toxicogenetics
  • Genetic toxicology
  • Genomics
Label
Essential concepts in toxicogenomics, edited by Donna L. Mendrick, William B. Mattes
Instantiates
Publication
Bibliography note
Includes bibliographical references and index
Carrier category
online resource
Carrier category code
  • cr
Carrier MARC source
rdacarrier
Color
multicolored
Content category
text
Content type code
  • txt
Content type MARC source
rdacontent
Contents
Toxicogenomics and classical toxicology, how to improve prediction and mechanistic understanding of human toxicity / Donna L. Mendrick -- Use of traditional endpoints and gene dysregulation to understand mechanisms of toxicity / Wayne R. Buck, Jeffrey F. Waring, Eric A. Blomme -- Quality control of microarray assays for toxicogenomic and in vitro diagnostic applications / Karol L. Thompson and Joseph Hackett -- Role of statistics in toxicogenomics / Michael Elashoff -- Predictive toxicogenomics in preclinical discovery / Scott A. Barros and Rory B. Martin -- In vivo predictive toxicogenomics / Mark W. Porter -- Bioinformatics, databasing and gene annotation / Lyle D. Burgoon and Timothy R. Zacharewski -- Microarray probe mapping and annotation in cross -- species comparative toxicogenomics / John N Calley, William B Mattes, Timothy P. Ryan -- Toxicogenomics in biomarker discovery -- Marc F. DeCristofaro, Kellye K. Daniels -- From pharmacogenomics to translational biomarkers / Donna L. Mendrick -- Public consortium efforts in toxicogenomics / William B. Mattes -- Applications of toxicogenomics to nonclinical drug development / Frank D. Sistare, Joseph J. DeGeorge
Control code
262841755
Dimensions
unknown
Extent
1 online resource (xi, 277 pages, 8 pages of plates)
Form of item
online
Isbn
9781603270489
Media category
computer
Media MARC source
rdamedia
Media type code
  • c
Other control number
10.1007/978-1-60327-048-9
Other physical details
illustrations (some color).
Sound
unknown sound
Specific material designation
remote
System control number
(OCoLC)262841755
Label
Essential concepts in toxicogenomics, edited by Donna L. Mendrick, William B. Mattes
Publication
Bibliography note
Includes bibliographical references and index
Carrier category
online resource
Carrier category code
  • cr
Carrier MARC source
rdacarrier
Color
multicolored
Content category
text
Content type code
  • txt
Content type MARC source
rdacontent
Contents
Toxicogenomics and classical toxicology, how to improve prediction and mechanistic understanding of human toxicity / Donna L. Mendrick -- Use of traditional endpoints and gene dysregulation to understand mechanisms of toxicity / Wayne R. Buck, Jeffrey F. Waring, Eric A. Blomme -- Quality control of microarray assays for toxicogenomic and in vitro diagnostic applications / Karol L. Thompson and Joseph Hackett -- Role of statistics in toxicogenomics / Michael Elashoff -- Predictive toxicogenomics in preclinical discovery / Scott A. Barros and Rory B. Martin -- In vivo predictive toxicogenomics / Mark W. Porter -- Bioinformatics, databasing and gene annotation / Lyle D. Burgoon and Timothy R. Zacharewski -- Microarray probe mapping and annotation in cross -- species comparative toxicogenomics / John N Calley, William B Mattes, Timothy P. Ryan -- Toxicogenomics in biomarker discovery -- Marc F. DeCristofaro, Kellye K. Daniels -- From pharmacogenomics to translational biomarkers / Donna L. Mendrick -- Public consortium efforts in toxicogenomics / William B. Mattes -- Applications of toxicogenomics to nonclinical drug development / Frank D. Sistare, Joseph J. DeGeorge
Control code
262841755
Dimensions
unknown
Extent
1 online resource (xi, 277 pages, 8 pages of plates)
Form of item
online
Isbn
9781603270489
Media category
computer
Media MARC source
rdamedia
Media type code
  • c
Other control number
10.1007/978-1-60327-048-9
Other physical details
illustrations (some color).
Sound
unknown sound
Specific material designation
remote
System control number
(OCoLC)262841755

Subject

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