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The Resource Evaluating the suitability of the human toenail as a biomonitor for manganese status : the one source cohort, by James M. Guthrie, (electronic resource)
Evaluating the suitability of the human toenail as a biomonitor for manganese status : the one source cohort, by James M. Guthrie, (electronic resource)
Resource Information
The item Evaluating the suitability of the human toenail as a biomonitor for manganese status : the one source cohort, by James M. Guthrie, (electronic resource) represents a specific, individual, material embodiment of a distinct intellectual or artistic creation found in University of Missouri Libraries.This item is available to borrow from all library branches.
Resource Information
The item Evaluating the suitability of the human toenail as a biomonitor for manganese status : the one source cohort, by James M. Guthrie, (electronic resource) represents a specific, individual, material embodiment of a distinct intellectual or artistic creation found in University of Missouri Libraries.
This item is available to borrow from all library branches.
- Summary
- Numerous studies have demonstrated that the human toenail is a reliable biomonitor for the intake of Se and other elements. The objective of this study was to evaluate the hypothesis that Mn intake is reflected in toenail Mn levels. Interest in the status of Mn, a necessary trace nutrient which may also have toxic effects upon overexposure, stems from two recent developments: first, a greater awareness of the role of Mn-based enzymes in human health, and second, a renewed controversy over the use of a Mn-containing gasoline additive in Canada. In order to evaluate the hypothesis, toenail specimens from One Source multivitamin users and matched controls were selected. Using the NAA technique, Se was measured using established methods, and then Mn was measured via a new procedure. The Se results confirmed the accurate classification of the cohort. However, the nail did not demonstrate significant, positive response to Mn supplementation. Several explanations for this lack of response may be offered, including the confounding effect of other, unknown dietary variables; Mn blood level regulation by homeostatic mechanisms; and the masking of endogenous Mn in the toenail by persistent Seleniumexogenous material
- Language
- eng
- Note
-
- The entire dissertation/thesis text is included in the research.pdf file; the official abstract appears in the short.pdf file (which also appears in the research.pdf); a non-technical general description, or public abstract, appears in the public.pdf file
- Title from title screen of research.pdf file (viewed on October 25, 2007)
- Vita
- Label
- Evaluating the suitability of the human toenail as a biomonitor for manganese status : the one source cohort
- Title
- Evaluating the suitability of the human toenail as a biomonitor for manganese status
- Title remainder
- the one source cohort
- Statement of responsibility
- by James M. Guthrie
- Language
- eng
- Summary
- Numerous studies have demonstrated that the human toenail is a reliable biomonitor for the intake of Se and other elements. The objective of this study was to evaluate the hypothesis that Mn intake is reflected in toenail Mn levels. Interest in the status of Mn, a necessary trace nutrient which may also have toxic effects upon overexposure, stems from two recent developments: first, a greater awareness of the role of Mn-based enzymes in human health, and second, a renewed controversy over the use of a Mn-containing gasoline additive in Canada. In order to evaluate the hypothesis, toenail specimens from One Source multivitamin users and matched controls were selected. Using the NAA technique, Se was measured using established methods, and then Mn was measured via a new procedure. The Se results confirmed the accurate classification of the cohort. However, the nail did not demonstrate significant, positive response to Mn supplementation. Several explanations for this lack of response may be offered, including the confounding effect of other, unknown dietary variables; Mn blood level regulation by homeostatic mechanisms; and the masking of endogenous Mn in the toenail by persistent Seleniumexogenous material
- Cataloging source
- MUU
- http://library.link/vocab/creatorName
- Guthrie, James McKamey
- Degree
- M.S.
- Dissertation year
- 2007.
- Granting institution
- University of Missouri-Columbia
- Illustrations
- illustrations
- Index
- no index present
- Literary form
- non fiction
- Nature of contents
-
- dictionaries
- bibliography
- theses
- http://library.link/vocab/relatedWorkOrContributorDate
- 1960-
- http://library.link/vocab/relatedWorkOrContributorName
- Robertson, John David
- http://library.link/vocab/subjectName
-
- Biological monitoring
- Toenails
- Selenium in human nutrition
- Manganese in human nutrition
- Target audience
- specialized
- Label
- Evaluating the suitability of the human toenail as a biomonitor for manganese status : the one source cohort, by James M. Guthrie, (electronic resource)
- Note
-
- The entire dissertation/thesis text is included in the research.pdf file; the official abstract appears in the short.pdf file (which also appears in the research.pdf); a non-technical general description, or public abstract, appears in the public.pdf file
- Title from title screen of research.pdf file (viewed on October 25, 2007)
- Vita
- Bibliography note
- Includes bibliographical references
- Carrier category
- online resource
- Carrier category code
-
- cr
- Carrier MARC source
- rdacarrier
- Color
- mixed
- Content category
- text
- Content type code
-
- txt
- Content type MARC source
- rdacontent
- Control code
- 176912802
- Dimensions
- unknown
- Form of item
- electronic
- Media category
- computer
- Media MARC source
- rdamedia
- Media type code
-
- c
- Specific material designation
- remote
- System control number
- (OCoLC)176912802
- System details
- Mode of access: World Wide Web
- Label
- Evaluating the suitability of the human toenail as a biomonitor for manganese status : the one source cohort, by James M. Guthrie, (electronic resource)
- Note
-
- The entire dissertation/thesis text is included in the research.pdf file; the official abstract appears in the short.pdf file (which also appears in the research.pdf); a non-technical general description, or public abstract, appears in the public.pdf file
- Title from title screen of research.pdf file (viewed on October 25, 2007)
- Vita
- Bibliography note
- Includes bibliographical references
- Carrier category
- online resource
- Carrier category code
-
- cr
- Carrier MARC source
- rdacarrier
- Color
- mixed
- Content category
- text
- Content type code
-
- txt
- Content type MARC source
- rdacontent
- Control code
- 176912802
- Dimensions
- unknown
- Form of item
- electronic
- Media category
- computer
- Media MARC source
- rdamedia
- Media type code
-
- c
- Specific material designation
- remote
- System control number
- (OCoLC)176912802
- System details
- Mode of access: World Wide Web
Library Locations
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Engineering Library & Technology CommonsBorrow itW2001 Lafferre Hall, Columbia, MO, 65211, US38.946102 -92.330125
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Fisher Delta Research CenterBorrow it2-64 Agricultural Bldg, Columbia, MO, 65201, US38.958397 -92.303491
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Geological Sciences LibraryBorrow it201 Geological Sciences, Columbia, MO, 65211, US38.947375 -92.329062
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J. Otto Lottes Health Sciences LibraryBorrow it1 Hospital Dr, Columbia, MO, 65201, US38.939544 -92.328377
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Journalism LibraryBorrow it102 Reynolds Jrnlism Institute, Columbia, MO, 65211, US38.947290 -92.328025
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Mathematical Sciences LibraryBorrow it104 Ellis Library, Columbia, MO, 65201, US38.944377 -92.326537
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University ArchivesBorrow itColumbia, MO, 65201, US
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University Archives McAlester AnnexBorrow it703 Lewis Hall, Columbia, MO, 65211, US38.934630 -92.342290
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University of Missouri Libraries DepositoryBorrow it2908 Lemone Blvd, Columbia, MO, 65211, US38.919360 -92.291620
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Zalk Veterinary Medical LibraryBorrow itVeterinary Medicine West, Columbia, MO, 65211, US38.941099 -92.317911
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<div class="citation" vocab="http://schema.org/"><i class="fa fa-external-link-square fa-fw"></i> Data from <span resource="http://link.library.missouri.edu/portal/Evaluating-the-suitability-of-the-human-toenail/azpYL9-Od7I/" typeof="Book http://bibfra.me/vocab/lite/Item"><span property="name http://bibfra.me/vocab/lite/label"><a href="http://link.library.missouri.edu/portal/Evaluating-the-suitability-of-the-human-toenail/azpYL9-Od7I/">Evaluating the suitability of the human toenail as a biomonitor for manganese status : the one source cohort, by James M. Guthrie, (electronic resource)</a></span> - <span property="potentialAction" typeOf="OrganizeAction"><span property="agent" typeof="LibrarySystem http://library.link/vocab/LibrarySystem" resource="http://link.library.missouri.edu/"><span property="name http://bibfra.me/vocab/lite/label"><a property="url" href="http://link.library.missouri.edu/">University of Missouri Libraries</a></span></span></span></span></div>
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<div class="citation" vocab="http://schema.org/"><i class="fa fa-external-link-square fa-fw"></i> Data from <span resource="http://link.library.missouri.edu/portal/Evaluating-the-suitability-of-the-human-toenail/azpYL9-Od7I/" typeof="Book http://bibfra.me/vocab/lite/Item"><span property="name http://bibfra.me/vocab/lite/label"><a href="http://link.library.missouri.edu/portal/Evaluating-the-suitability-of-the-human-toenail/azpYL9-Od7I/">Evaluating the suitability of the human toenail as a biomonitor for manganese status : the one source cohort, by James M. Guthrie, (electronic resource)</a></span> - <span property="potentialAction" typeOf="OrganizeAction"><span property="agent" typeof="LibrarySystem http://library.link/vocab/LibrarySystem" resource="http://link.library.missouri.edu/"><span property="name http://bibfra.me/vocab/lite/label"><a property="url" href="http://link.library.missouri.edu/">University of Missouri Libraries</a></span></span></span></span></div>