The Resource Flourescent molecular rotors as mechanosensors in biofluids, by Walter John Akers, (electronic resource)

Flourescent molecular rotors as mechanosensors in biofluids, by Walter John Akers, (electronic resource)

Label
Flourescent molecular rotors as mechanosensors in biofluids
Title
Flourescent molecular rotors as mechanosensors in biofluids
Statement of responsibility
by Walter John Akers
Creator
Contributor
Thesis advisor
Subject
Genre
Language
eng
Summary
Many disease states have associated blood viscosity changes. Molecular rotors, fluorescent molecules with viscosity sensitive quantum yields, have recently been investigated as a new method for biofluid viscosity measurement. Biofluid viscosity measurements by conventional methods are complicated by protein adherence to surfaces and formation of air-surface layers. The presented work demonstrates the usefulness of fluorescence viscometry using molecular rotors dissolved in aqueous solutions and blood plasma. The precision of fluorescence viscometry is compared with that of a state-of-the-art cone and plate viscometer. The interaction of molecular rotors in solution with blood plasma proteins is reported. The viscosity sensitivity of surfaceimmobilized molecular rotors to glass nanoparticles and optical fibers is also investigated. Conclusions: fluorescence viscometry using molecular rotors promises to be a powerful new method for biofluid viscosity measurement, delivering fast readout for microliter volume samples
Cataloging source
MUU
http://library.link/vocab/creatorDate
1975-
http://library.link/vocab/creatorName
Akers, Walter John
Degree
Ph. D.
Dissertation year
2005.
Granting institution
University of Missouri-Columbia
Illustrations
illustrations
Index
no index present
Literary form
non fiction
Nature of contents
  • dictionaries
  • bibliography
  • theses
http://library.link/vocab/relatedWorkOrContributorName
Haidekker, Mark A.
http://library.link/vocab/subjectName
  • Blood
  • Biomechanics
  • Body fluid flow
Target audience
specialized
Label
Flourescent molecular rotors as mechanosensors in biofluids, by Walter John Akers, (electronic resource)
Instantiates
Publication
Note
  • The entire dissertation/thesis text is included in the research.pdf file; the official abstract appears in the short.pdf file (which also appears in the research.pdf); a non-technical general description, or public abstract, appears in the public.pdf file
  • Title from title screen of research.pdf file (viewed on October 19, 2007)
  • Vita
Bibliography note
Includes bibliographical references
Carrier category
online resource
Carrier category code
cr
Carrier MARC source
rdacarrier
Color
mixed
Content category
text
Content type code
txt
Content type MARC source
rdacontent
Control code
174965401
Dimensions
unknown
Form of item
electronic
Media category
computer
Media MARC source
rdamedia
Media type code
c
Specific material designation
remote
System control number
(OCoLC)174965401
System details
Mode of access: World Wide Web
Label
Flourescent molecular rotors as mechanosensors in biofluids, by Walter John Akers, (electronic resource)
Publication
Note
  • The entire dissertation/thesis text is included in the research.pdf file; the official abstract appears in the short.pdf file (which also appears in the research.pdf); a non-technical general description, or public abstract, appears in the public.pdf file
  • Title from title screen of research.pdf file (viewed on October 19, 2007)
  • Vita
Bibliography note
Includes bibliographical references
Carrier category
online resource
Carrier category code
cr
Carrier MARC source
rdacarrier
Color
mixed
Content category
text
Content type code
txt
Content type MARC source
rdacontent
Control code
174965401
Dimensions
unknown
Form of item
electronic
Media category
computer
Media MARC source
rdamedia
Media type code
c
Specific material designation
remote
System control number
(OCoLC)174965401
System details
Mode of access: World Wide Web

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