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The Resource Gene targeting : a practical approach, edited by Alexandra L. Joyner

Gene targeting : a practical approach, edited by Alexandra L. Joyner

Label
Gene targeting : a practical approach
Title
Gene targeting
Title remainder
a practical approach
Statement of responsibility
edited by Alexandra L. Joyner
Contributor
Subject
Genre
Language
eng
Summary
  • "This new edition of Gene Targeting: A Practical Approach contains a remarkable collection of state-of-the-art protocols as well as thoughtful discussion of how to design a new mouse mutation and analyse the resulting phenotype to maximise the information gained. The techniques described for gene targeting in mouse ES cells, are equally applicable for gene targeting in other tissue culture cells, including human cells. The second edition describes additional genetic approaches for studying gene function in mice, including chimera analysis, gene trap (GT) approaches and powerful ways to combine gene targeting with classical genetics." "Gene Targeting: A Practical Approach (second edition) is a practical tool and information resource for scientists working on fundamental or applied aspects of gene targeting, ES cell manipulation, and analysis of mouse mutants. It will be invaluable to all researchers who wish to use the approaches for studies of gene function in cells or mice."--Jacket
  • "This new edition of Gene Targeting: A Practical Approach contains a remarkable collection of state-of-the-art protocols as well as thoughtful discussion of how to design a new mouse mutation and analyse the resulting phenotype to maximise the information gained. The techniques described for gene targeting in mouse ES cells, are equally applicable for gene targeting in other tissue culture cells, including human cells. The second edition describes additional genetic approaches for studying gene function in mice, including chimera analysis, gene trap (GT) approaches and powerful ways to combine gene targeting with classical genetics." "Gene Targeting: A Practical Approach (second edition) is a practical tool and information resource for scientists working on fundamental or applied aspects of gene targeting, ES cell manipulation, and analysis of mouse mutants. It will be invaluable to all researchers who wish to use the approaches for studies of gene function in cells or mice."--BOOK JACKET
Member of
Cataloging source
DLC
Dewey number
660.6/5
Illustrations
illustrations
Index
index present
LC call number
QH442
LC item number
.G456 2000
Literary form
non fiction
NAL call number
QH442.3
NAL item number
.G456 2000
Nature of contents
bibliography
http://library.link/vocab/relatedWorkOrContributorName
Joyner, Alexandra L
Series statement
Practical approach series
http://library.link/vocab/subjectName
  • Gene targeting
  • Cell Line
  • Gene Targeting
  • Genetic Vectors
  • Stem Cells
Label
Gene targeting : a practical approach, edited by Alexandra L. Joyner
Instantiates
Publication
Bibliography note
Includes bibliographical references and index
Carrier category
volume
Carrier category code
nc
Carrier MARC source
rdacarrier
Content category
text
Content type code
txt
Content type MARC source
rdacontent
Contents
Gene targeting, principles, and practice in mammalian cells / Paul Hasty, Alejandro Abuin, and Allan Bradley -- Site-specific recombination in cells and mice / Susan M. Dymecki -- Production of targeted embryonic stem cell clones / Michael P. Matise, Wojtek Auerbach and Alexandra L. Joyner -- Production of chimeras by blastocyst and morula injection of targeted ES cells / Virginia Papaioannou and Randall Johnson -- Production and analysis of ES cell aggregation chimeras / Andreas Nagy and Janet Rossant -- Gene trap strategies in ES cells / Wolfgang Wurst and Achim Gossler -- Classical genetics and gene targeting / Scott Bultman and Terry Magnuson
Control code
41649667
Dimensions
25 cm
Edition
2nd ed.
Extent
xviii, 293 pages
Isbn
9780199637935
Isbn Type
(hbk.)
Lccn
99036660
Media category
unmediated
Media MARC source
rdamedia
Media type code
n
Other physical details
illustrations
Label
Gene targeting : a practical approach, edited by Alexandra L. Joyner
Publication
Bibliography note
Includes bibliographical references and index
Carrier category
volume
Carrier category code
nc
Carrier MARC source
rdacarrier
Content category
text
Content type code
txt
Content type MARC source
rdacontent
Contents
Gene targeting, principles, and practice in mammalian cells / Paul Hasty, Alejandro Abuin, and Allan Bradley -- Site-specific recombination in cells and mice / Susan M. Dymecki -- Production of targeted embryonic stem cell clones / Michael P. Matise, Wojtek Auerbach and Alexandra L. Joyner -- Production of chimeras by blastocyst and morula injection of targeted ES cells / Virginia Papaioannou and Randall Johnson -- Production and analysis of ES cell aggregation chimeras / Andreas Nagy and Janet Rossant -- Gene trap strategies in ES cells / Wolfgang Wurst and Achim Gossler -- Classical genetics and gene targeting / Scott Bultman and Terry Magnuson
Control code
41649667
Dimensions
25 cm
Edition
2nd ed.
Extent
xviii, 293 pages
Isbn
9780199637935
Isbn Type
(hbk.)
Lccn
99036660
Media category
unmediated
Media MARC source
rdamedia
Media type code
n
Other physical details
illustrations

Library Locations

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      1020 Lowry Street, Columbia, MO, 65201, US
      38.944491 -92.326012
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