Coverart for item
The Resource Genetic toxicology : principles and methods, edited by James M. Parry, Elizabeth M. Parry

Genetic toxicology : principles and methods, edited by James M. Parry, Elizabeth M. Parry

Label
Genetic toxicology : principles and methods
Title
Genetic toxicology
Title remainder
principles and methods
Statement of responsibility
edited by James M. Parry, Elizabeth M. Parry
Contributor
Subject
Genre
Language
eng
Summary
The evaluation of potential mutagenic activity is a critical step in the assessment of the safety of both new and pre-existing chemical types. In Genetic Toxicology: Principles and Methods, expert contributors help to satisfy the demand for education in this tremendously important area of study. The volume covers three basic areas: the scientific basis of the discipline, the methodologies of the main test assays, and the application of the methods, all aimed primarily at scientists in the safety departments of the industries working with both natural and synthetic chemicals. Written in the highly successful Methods in Molecular Biology"!series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Intuitive and cutting-edge, Genetic Toxicology: Principles and Methods provides crucial support to both laboratory workers in providing quality information on the appropriate application of techniques and to study directors in their assay selection and protocol design in this vital field
Member of
Cataloging source
GW5XE
Dewey number
615.9
Illustrations
illustrations
Index
index present
Language note
English
LC call number
RA1224.3
LC item number
.G46 2012
Literary form
non fiction
Nature of contents
  • dictionaries
  • bibliography
NLM call number
  • W1
  • QU 25
NLM item number
ME9616J v.817 2012
http://library.link/vocab/relatedWorkOrContributorName
  • Parry, J. M
  • Parry, Elizabeth M
Series statement
Methods in molecular biology,
Series volume
817
http://library.link/vocab/subjectName
  • Genetic toxicology
  • Mutagenicity Tests
  • Mutagens
  • Genetic toxicology
Label
Genetic toxicology : principles and methods, edited by James M. Parry, Elizabeth M. Parry
Instantiates
Publication
Antecedent source
unknown
Bibliography note
Includes bibliographical references and index
Carrier category
online resource
Carrier category code
  • cr
Carrier MARC source
rdacarrier
Color
multicolored
Content category
text
Content type code
  • txt
Content type MARC source
rdacontent
Contents
The application of structure-activity relationships to the prediction of the mutagenic activity of chemicals -- Bacterial mutagenicity assays: Test methods -- The mouse lymphoma assay -- Mammalian cell HPRT gene mutation assay: Test methods -- The in vitro mammalian chromosome aberration test -- The interpretation and analysis of cytogenetic data -- The in vitro micronucleus assay -- The in vitro and in vivo comet assays -- Assessment of DNA interstrand crosslinks using the modified alkaline comet assay -- (32)p-postlabelling for the sensitive detection of DNA adducts -- Methods for the detection of DNA adducts -- The GADD45a-GFP GreenScreen HC assay -- Real-time reverse-transcription polymerase chain reaction: Technical considerations for gene expression analysis -- Cytogenetic in vivo assays in somatic cells -- Cytogenetic methods in human biomonitoring: Principles and uses -- The measurement of induced genetic change in mammalian germ cells -- Transgenic animal mutation models: A review of the models and how they function -- Analysis of genotoxicity data in a regulatory context
Control code
769663569
Dimensions
unknown
Extent
1 online resource (xvi, 433 pages)
File format
unknown
Form of item
online
Isbn
9781617794209
Level of compression
unknown
Media category
computer
Media MARC source
rdamedia
Media type code
  • c
Other control number
10.1007/978-1-61779-421-6.
Other physical details
illustrations.
Quality assurance targets
not applicable
Reformatting quality
unknown
Sound
unknown sound
Specific material designation
remote
System control number
(OCoLC)769663569
Label
Genetic toxicology : principles and methods, edited by James M. Parry, Elizabeth M. Parry
Publication
Antecedent source
unknown
Bibliography note
Includes bibliographical references and index
Carrier category
online resource
Carrier category code
  • cr
Carrier MARC source
rdacarrier
Color
multicolored
Content category
text
Content type code
  • txt
Content type MARC source
rdacontent
Contents
The application of structure-activity relationships to the prediction of the mutagenic activity of chemicals -- Bacterial mutagenicity assays: Test methods -- The mouse lymphoma assay -- Mammalian cell HPRT gene mutation assay: Test methods -- The in vitro mammalian chromosome aberration test -- The interpretation and analysis of cytogenetic data -- The in vitro micronucleus assay -- The in vitro and in vivo comet assays -- Assessment of DNA interstrand crosslinks using the modified alkaline comet assay -- (32)p-postlabelling for the sensitive detection of DNA adducts -- Methods for the detection of DNA adducts -- The GADD45a-GFP GreenScreen HC assay -- Real-time reverse-transcription polymerase chain reaction: Technical considerations for gene expression analysis -- Cytogenetic in vivo assays in somatic cells -- Cytogenetic methods in human biomonitoring: Principles and uses -- The measurement of induced genetic change in mammalian germ cells -- Transgenic animal mutation models: A review of the models and how they function -- Analysis of genotoxicity data in a regulatory context
Control code
769663569
Dimensions
unknown
Extent
1 online resource (xvi, 433 pages)
File format
unknown
Form of item
online
Isbn
9781617794209
Level of compression
unknown
Media category
computer
Media MARC source
rdamedia
Media type code
  • c
Other control number
10.1007/978-1-61779-421-6.
Other physical details
illustrations.
Quality assurance targets
not applicable
Reformatting quality
unknown
Sound
unknown sound
Specific material designation
remote
System control number
(OCoLC)769663569

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