Coverart for item
The Resource Genome-based therapeutics : targeted drug discovery and development : workshop summary, Adam C. Berger and Steve Olson, rapporteurs ; Roundtable on Translating Genomic-Based Research for Health, Board on Health Sciences Policy, Institute of Medicine of the National Academies

Genome-based therapeutics : targeted drug discovery and development : workshop summary, Adam C. Berger and Steve Olson, rapporteurs ; Roundtable on Translating Genomic-Based Research for Health, Board on Health Sciences Policy, Institute of Medicine of the National Academies

Label
Genome-based therapeutics : targeted drug discovery and development : workshop summary
Title
Genome-based therapeutics
Title remainder
targeted drug discovery and development : workshop summary
Statement of responsibility
Adam C. Berger and Steve Olson, rapporteurs ; Roundtable on Translating Genomic-Based Research for Health, Board on Health Sciences Policy, Institute of Medicine of the National Academies
Title variation
Targeted drug discovery and development
Contributor
Subject
Genre
Language
eng
Summary
"The number of new drug approvals has remained reasonably steady for the past 50 years at around 20 to 30 per year, while at the same time the total spending on health-related research and development has tripled since 1990. There are many suspected causes for this trend, including increases in regulatory barriers, the rising costs of scientific inquiry, a decrease in research and development efficiency, the downstream effects of patient expirations on investment, and the lack of production models that have successfully incorporated new technology. Regardless, this trajectory is not economically sustainable for the businesses involved, and, in response, many companies are turning toward collaborative models of drug development, whether with other industrial firms, academia, or government. Introducing greater efficiency and knowledge into these new models and aligning incentives among participants may help to reverse the trends highlighted above, while producing more effective drugs in the process. Genome-based therapeutics explains that new technologies have the potential to open up avenues of development and to identify new drug targets to pursue. Specifically, improved validation of gene-disease associations through genomics research has the potential to revolutionize drug production and lower development costs. Genetic information has helped developers by increasing their understanding of the mechanisms of disease as well as individual patients' reactions to their medications. There is a need to identify the success factors for the various models that are being developed, whether they are industry-led, academia-led, or collaborations between the two. Genome-Based Therapeutics summarizes a workshop that was held on March 21, 2012, titled New paradigms in drug discovery: how genomic data are being used to revolutionize the drug discovery and development process. At this workshop the goal was to examine the general approaches being used to apply successes achieved so far, and the challenges ahead"--Publisher's description
Member of
Cataloging source
COO
Dewey number
615.1
Illustrations
illustrations
Index
no index present
LC call number
RS420
LC item number
.G4 2012eb
Literary form
non fiction
Nature of contents
  • dictionaries
  • bibliography
NLM call number
QV 745
http://library.link/vocab/relatedWorkOrContributorDate
1956-
http://library.link/vocab/relatedWorkOrContributorName
  • Berger, Adam C
  • Olson, Steve
  • Institute of Medicine (U.S.)
http://library.link/vocab/subjectName
  • Drugs
  • Pharmaceutical technology
  • Pharmaceutical industry
  • Genomics
  • Drug Discovery
  • Genetic Therapy
  • United States
  • MEDICAL
  • Drugs
  • Genomics
  • Pharmaceutical industry
  • Pharmaceutical technology
  • United States
Label
Genome-based therapeutics : targeted drug discovery and development : workshop summary, Adam C. Berger and Steve Olson, rapporteurs ; Roundtable on Translating Genomic-Based Research for Health, Board on Health Sciences Policy, Institute of Medicine of the National Academies
Instantiates
Publication
Bibliography note
Includes bibliographical references
Carrier category
online resource
Carrier category code
  • cr
Carrier MARC source
rdacarrier
Content category
text
Content type code
  • txt
Content type MARC source
rdacontent
Contents
Introduction -- The current landscape -- Case studies -- Emerging technologies in drug development -- Evolving paradigms -- Forging collaborative strategies for the development of personalized medicine
Control code
817900348
Extent
1 online resource (90 pages)
Form of item
online
Isbn
9780309260251
Lccn
2012554410
Media category
computer
Media MARC source
rdamedia
Media type code
  • c
Other physical details
illustrations
Specific material designation
remote
System control number
(OCoLC)817900348
Label
Genome-based therapeutics : targeted drug discovery and development : workshop summary, Adam C. Berger and Steve Olson, rapporteurs ; Roundtable on Translating Genomic-Based Research for Health, Board on Health Sciences Policy, Institute of Medicine of the National Academies
Publication
Bibliography note
Includes bibliographical references
Carrier category
online resource
Carrier category code
  • cr
Carrier MARC source
rdacarrier
Content category
text
Content type code
  • txt
Content type MARC source
rdacontent
Contents
Introduction -- The current landscape -- Case studies -- Emerging technologies in drug development -- Evolving paradigms -- Forging collaborative strategies for the development of personalized medicine
Control code
817900348
Extent
1 online resource (90 pages)
Form of item
online
Isbn
9780309260251
Lccn
2012554410
Media category
computer
Media MARC source
rdamedia
Media type code
  • c
Other physical details
illustrations
Specific material designation
remote
System control number
(OCoLC)817900348

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