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The Resource Genotoxic impurities : strategies for identification and control, edited by Andrew Teasdale

Genotoxic impurities : strategies for identification and control, edited by Andrew Teasdale

Label
Genotoxic impurities : strategies for identification and control
Title
Genotoxic impurities
Title remainder
strategies for identification and control
Statement of responsibility
edited by Andrew Teasdale
Contributor
Subject
Language
eng
Cataloging source
DNLM/DLC
Illustrations
illustrations
Index
index present
LC call number
RA1224.3
LC item number
.G463 2010
Literary form
non fiction
Nature of contents
bibliography
NLM call number
QU 450
NLM item number
G3353 2010
http://library.link/vocab/relatedWorkOrContributorName
Teasdale, Andrew
http://library.link/vocab/subjectName
  • Genetic toxicology
  • Drugs
  • Mutagenicity Tests
  • Drug-Related Side Effects and Adverse Reactions
  • Mutagens
  • Mutagens
  • Toxicogenetics
Label
Genotoxic impurities : strategies for identification and control, edited by Andrew Teasdale
Instantiates
Publication
Bibliography note
Includes bibliographical references and index
Carrier category
volume
Carrier category code
  • nc
Carrier MARC source
rdacarrier
Content category
text
Content type code
  • txt
Content type MARC source
rdacontent
Contents
Development of genotoxic impurities guidelines and the threshold of toxicological concern concept -- Historical overview of the development of genotoxic impurities guidelines and their impact / Ron Ogilvie, Andrew Teasdale -- Development of the threshold of toxicological concern concept and its relationship to duration of exposure / Alessandro Brigo, Lutz Müller -- Evaluation of genotoxic risk from a preclincial perspective -- Genetic toxicity testing to qualify alerting impurities / Mike O'Donovan -- Use of structure activity relationship evaluation as a critical tool in the evaluation of the genotoxic potential of impurities / Susanne Glowienke, Catrin Hasselgren -- Compound-specific risk assessments for genotoxic impurities : examples and issues / Andrew Teasdale, Charles Humfrey -- Human genotoxic metabolites : identification and risk management / Krista Dobo, Don Walker, Andrew Teasdale --Perspective on risk posed by genotoxic impurities -- Genotoxic thresholds / Gareth Jenkins ... [et al.] -- Genotoxic impurities : a risk in perspective / Dave Elder, Jim Harvey -- Assessment of genotoxic risk: quality perspective -- Strategies for the evaluation of genotoxic impurity risk / Andrew Teasdale, Dave Elder, Simon Fenner -- Analysis of genotoxic impurities : review of approaches / Dave Elder -- Development of a strategy for analysis of genotoxic impurities / Andrew Baker -- Strategic approaches to the chromatographic analysis of genotoxic impurities / Frank David ... [et al.] -- Analysis of genotoxic impurities by nuclear magnetic resonance spectroscopy / Andrew Phillips -- Mechanism and processing parameters affecting the formation of sulfonate esters : summary of the Product Quality Research Institute studies / Andrew Teasdale -- Aspects to consider when low-level active pharmaceutical ingredient/drug product degradants have the potential for genotoxicity / Alan P. McKeown, Andrew Teasdale
Control code
643443212
Dimensions
25 cm
Extent
xiii, 428 pages
Isbn
9780470499191
Isbn Type
(cloth)
Lccn
2010025374
Media category
unmediated
Media MARC source
rdamedia
Media type code
  • n
Other physical details
illustrations
System control number
(OCoLC)643443212
Label
Genotoxic impurities : strategies for identification and control, edited by Andrew Teasdale
Publication
Bibliography note
Includes bibliographical references and index
Carrier category
volume
Carrier category code
  • nc
Carrier MARC source
rdacarrier
Content category
text
Content type code
  • txt
Content type MARC source
rdacontent
Contents
Development of genotoxic impurities guidelines and the threshold of toxicological concern concept -- Historical overview of the development of genotoxic impurities guidelines and their impact / Ron Ogilvie, Andrew Teasdale -- Development of the threshold of toxicological concern concept and its relationship to duration of exposure / Alessandro Brigo, Lutz Müller -- Evaluation of genotoxic risk from a preclincial perspective -- Genetic toxicity testing to qualify alerting impurities / Mike O'Donovan -- Use of structure activity relationship evaluation as a critical tool in the evaluation of the genotoxic potential of impurities / Susanne Glowienke, Catrin Hasselgren -- Compound-specific risk assessments for genotoxic impurities : examples and issues / Andrew Teasdale, Charles Humfrey -- Human genotoxic metabolites : identification and risk management / Krista Dobo, Don Walker, Andrew Teasdale --Perspective on risk posed by genotoxic impurities -- Genotoxic thresholds / Gareth Jenkins ... [et al.] -- Genotoxic impurities : a risk in perspective / Dave Elder, Jim Harvey -- Assessment of genotoxic risk: quality perspective -- Strategies for the evaluation of genotoxic impurity risk / Andrew Teasdale, Dave Elder, Simon Fenner -- Analysis of genotoxic impurities : review of approaches / Dave Elder -- Development of a strategy for analysis of genotoxic impurities / Andrew Baker -- Strategic approaches to the chromatographic analysis of genotoxic impurities / Frank David ... [et al.] -- Analysis of genotoxic impurities by nuclear magnetic resonance spectroscopy / Andrew Phillips -- Mechanism and processing parameters affecting the formation of sulfonate esters : summary of the Product Quality Research Institute studies / Andrew Teasdale -- Aspects to consider when low-level active pharmaceutical ingredient/drug product degradants have the potential for genotoxicity / Alan P. McKeown, Andrew Teasdale
Control code
643443212
Dimensions
25 cm
Extent
xiii, 428 pages
Isbn
9780470499191
Isbn Type
(cloth)
Lccn
2010025374
Media category
unmediated
Media MARC source
rdamedia
Media type code
  • n
Other physical details
illustrations
System control number
(OCoLC)643443212

Library Locations

    • J. Otto Lottes Health Sciences LibraryBorrow it
      1 Hospital Dr, Columbia, MO, 65201, US
      38.939544 -92.328377
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