Coverart for item
The Resource Glutamate-related biomarkers in drug development for disorders of the nervous system : workshop summary, Diana E. Pankevich, Miriam Davis, and Bruce M. Altevogt, rapporteurs ; Forum on Neuroscience and Nervous System Disorders, Board on Health Sciences Policy, Institute of Medicine of the National Academies

Glutamate-related biomarkers in drug development for disorders of the nervous system : workshop summary, Diana E. Pankevich, Miriam Davis, and Bruce M. Altevogt, rapporteurs ; Forum on Neuroscience and Nervous System Disorders, Board on Health Sciences Policy, Institute of Medicine of the National Academies

Label
Glutamate-related biomarkers in drug development for disorders of the nervous system : workshop summary
Title
Glutamate-related biomarkers in drug development for disorders of the nervous system
Title remainder
workshop summary
Statement of responsibility
Diana E. Pankevich, Miriam Davis, and Bruce M. Altevogt, rapporteurs ; Forum on Neuroscience and Nervous System Disorders, Board on Health Sciences Policy, Institute of Medicine of the National Academies
Contributor
Subject
Genre
Language
eng
Summary
Glutamate is the most pervasive neurotransmitter in the central nervous system (CNS). Despite this fact, no validated biological markers, or biomarkers, currently exist for measuring glutamate pathology in CNS disorders or injuries. Glutamate dysfunction has been associated with an extensive range of nervous system diseases and disorders. Problems with how the neurotransmitter glutamate functions in the brain have been linked to a wide variety of disorders, including schizophrenia, Alzheimer's, substance abuse, and traumatic brain injury. These conditions are widespread, affecting a large portion of the United States population, and remain difficult to treat. Efforts to understand, treat, and prevent glutamate-related disorders can be aided by the identification of valid biomarkers. The Institute of Medicine's Forum on Neuroscience and Nervous System Disorders held a workshop on June 21-22, 2010, to explore ways to accelerate the development, validation, and implementation of such biomarkers. This book investigates promising current and emerging technologies, and outlines strategies to procure resources and tools to advance drug development for associated nervous system disorders. Moreover, this report highlights presentations by expert panelists, and the open panel discussions that occurred during the workshop
Member of
Cataloging source
N$T
Dewey number
610.28
Illustrations
illustrations
Index
no index present
LC call number
R853.B54
LC item number
G58 2011eb
Literary form
non fiction
Nature of contents
  • dictionaries
  • bibliography
NLM call number
WL 141
http://library.link/vocab/relatedWorkOrContributorDate
1975-
http://library.link/vocab/relatedWorkOrContributorName
  • Pankevich, Diana E.
  • Altevogt, Bruce M
  • Davis, Miriam
  • Institute of Medicine (U.S.)
http://library.link/vocab/subjectName
  • Biochemical markers
  • Drug development
  • Nervous system
  • Neuropharmacology
  • Biomarkers, Pharmacological
  • Central Nervous System Diseases
  • Central Nervous System
  • Drug Discovery
  • Glutamic Acid
  • Neuropharmacology
  • MEDICAL
  • MEDICAL
  • MEDICAL
  • MEDICAL
  • TECHNOLOGY & ENGINEERING
  • Biochemical markers
  • Drug development
  • Nervous system
  • Neuropharmacology
Label
Glutamate-related biomarkers in drug development for disorders of the nervous system : workshop summary, Diana E. Pankevich, Miriam Davis, and Bruce M. Altevogt, rapporteurs ; Forum on Neuroscience and Nervous System Disorders, Board on Health Sciences Policy, Institute of Medicine of the National Academies
Instantiates
Publication
Antecedent source
unknown
Bibliography note
Includes bibliographical references (pages 39-43)
Carrier category
online resource
Carrier category code
  • cr
Carrier MARC source
rdacarrier
Color
multicolored
Content category
text
Content type code
  • txt
Content type MARC source
rdacontent
Contents
  • Registered Attendees
  • Appendix C:
  • Agenda
  • Introduction
  • Overview of the Glutamatergic System
  • Glutamate Biomarkers
  • Treatment Implications of Biomarkers
  • Challenges and Opportunities
  • Appendix A:
  • References
  • Appendix B:
Control code
756496245
Dimensions
unknown
Extent
1 online resource (xii, 61 pages)
File format
unknown
Form of item
online
Isbn
9780309212229
Lccn
2011275018
Level of compression
unknown
Media category
computer
Media MARC source
rdamedia
Media type code
  • c
Other physical details
illustrations (some color)
Quality assurance targets
not applicable
Reformatting quality
unknown
Sound
unknown sound
Specific material designation
remote
System control number
(OCoLC)756496245
Label
Glutamate-related biomarkers in drug development for disorders of the nervous system : workshop summary, Diana E. Pankevich, Miriam Davis, and Bruce M. Altevogt, rapporteurs ; Forum on Neuroscience and Nervous System Disorders, Board on Health Sciences Policy, Institute of Medicine of the National Academies
Publication
Antecedent source
unknown
Bibliography note
Includes bibliographical references (pages 39-43)
Carrier category
online resource
Carrier category code
  • cr
Carrier MARC source
rdacarrier
Color
multicolored
Content category
text
Content type code
  • txt
Content type MARC source
rdacontent
Contents
  • Registered Attendees
  • Appendix C:
  • Agenda
  • Introduction
  • Overview of the Glutamatergic System
  • Glutamate Biomarkers
  • Treatment Implications of Biomarkers
  • Challenges and Opportunities
  • Appendix A:
  • References
  • Appendix B:
Control code
756496245
Dimensions
unknown
Extent
1 online resource (xii, 61 pages)
File format
unknown
Form of item
online
Isbn
9780309212229
Lccn
2011275018
Level of compression
unknown
Media category
computer
Media MARC source
rdamedia
Media type code
  • c
Other physical details
illustrations (some color)
Quality assurance targets
not applicable
Reformatting quality
unknown
Sound
unknown sound
Specific material designation
remote
System control number
(OCoLC)756496245

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