Coverart for item
The Resource Guidance for the description of animal research in scientific publications, Institute for Laboratory Animal Research, Division on Earth and Life Studies, National Research Council of the National Academies, (electronic resource)

Guidance for the description of animal research in scientific publications, Institute for Laboratory Animal Research, Division on Earth and Life Studies, National Research Council of the National Academies, (electronic resource)

Label
Guidance for the description of animal research in scientific publications
Title
Guidance for the description of animal research in scientific publications
Statement of responsibility
Institute for Laboratory Animal Research, Division on Earth and Life Studies, National Research Council of the National Academies
Contributor
Subject
Language
eng
Summary
  • The committee (Committee on Guidelines for Scientific Publications Involving Animal Studies) believes that journal editors have a role to play in promoting the proper use of animals in research through the publication of adequate descriptions. The committee urges journal editors to actively promote effective and ethical research by encouraging the provision of sufficient information to enable assessment and interpretation of research findings and advancement of knowledge based on reproducible results. This report provides journal editors, authors, and reviewers with guidance (and supporting references) for effective reporting of animal research in published articles based on adequate descriptions of the research animal (section 3), with detailed information about the animals' age, sex, weight, and life stage (3.1), source (3.2), genetic nomenclature (3.3), microbial/pathogen status (3.4), and preparation and assignment (including control groups)(3.5); and the research animal environment (sections 4 and, for aquatic animals, 6), with detailed information about the micro- and macroenvironment (4.4 and 6.1), diet (4.1 and 6.2),water (4.2), and housing (4.3 and 6.3);3. basic animal methodology, including aspects of animal care and use that can affect research outcomes (section 5), with detailed information about experimental effects (5.1), administration of substances (5.2), use of infectious agents (5.3), sample acquisition (5.4), and euthanasia (5.5).The ability to interpret, evaluate, and reproduce biomedical and other types of laboratory animal research and testing is a reasonable minimum standard for the assessment of effective reporting in research articles. Journal editors can substantially contribute to the achievement of this standard through the articulation of clear policies and criteria for their authors and reviewers. This report complements existing checklists and resources by providing guidance and scientific evidence for the specific types of information that should be included in research publications to promote the advancement of science involving animal studies. It also describes approaches to facilitate the provision of such information
  • "The publication of research articles involving animal studies is central to many disciplines in science and biomedicine. Effective descriptions in such publications enable researchers to interpret the data, evaluate and replicate findings, and move the science forward. Analyses of published studies with research animals have demonstrated numerous deficiencies in the reporting of details in research methods for animal studies. Considerable variation in the amount of information required by scientific publications and reported by authors undermines this basic scientific principle and results in the unnecessary use of animals and other resources in failed efforts to reproduce study results. Guidance for the description of animal research in scientific publications outlines the information that should be included in scientific papers regarding the animal studies to ensure that the study can be replicated. The report urges journal editors to actively promote effective and ethical research by encouraging the provision of sufficient information. Examples of this information include: conditions of housing and husbandry, genetic nomenclature, microbial status, detailed experimental manipulations, and handling and use of pharmaceuticals. Inclusion of this information will enable assessment and interpretation of research findings and advancement of knowledge based on reproducible results.--Publisher's description
Cataloging source
DNLM
Funding information
This study was supported by core funding for the Institute for Laboratory Animal Research from the National Science Foundation under contract DBI-0838150; the US Department of the Army under contract W81XWH-09-1-0664; the US Department of the Navy under contract N00014-05-G-0288, Task Order #21; and the Department of Health and Human Services/National Institutes of Health under contract N01-OD-4-2139, Task Order #221.
NLM call number
W 20.55.A5
http://library.link/vocab/relatedWorkOrContributorName
  • Institute for Laboratory Animal Research (U.S.)
  • Institute for Laboratory Animal Research (U.S.)
http://library.link/vocab/subjectName
  • Animal Experimentation
  • Animals, Laboratory
  • Research Design
  • Reproducibility of Results
  • Research Report
  • Editorial Policies
  • United States
  • United States
Label
Guidance for the description of animal research in scientific publications, Institute for Laboratory Animal Research, Division on Earth and Life Studies, National Research Council of the National Academies, (electronic resource)
Instantiates
Publication
Bibliography note
Includes bibliographical references
Contents
Overview -- Defining an optimal description of an animal study -- The research animal -- The research animal environment (study conditions) -- Basic animal methodology -- Aquatic systems -- Summary and conclusions
Control code
OCM1bookssj0000595466
Dimensions
unknown
Isbn
9780309219518
Specific material designation
remote
System control number
(WaSeSS)bookssj0000595466
System details
Description based on online resource; title from PDF title page (viewed on May 21, 2012)
Label
Guidance for the description of animal research in scientific publications, Institute for Laboratory Animal Research, Division on Earth and Life Studies, National Research Council of the National Academies, (electronic resource)
Publication
Bibliography note
Includes bibliographical references
Contents
Overview -- Defining an optimal description of an animal study -- The research animal -- The research animal environment (study conditions) -- Basic animal methodology -- Aquatic systems -- Summary and conclusions
Control code
OCM1bookssj0000595466
Dimensions
unknown
Isbn
9780309219518
Specific material designation
remote
System control number
(WaSeSS)bookssj0000595466
System details
Description based on online resource; title from PDF title page (viewed on May 21, 2012)

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