The Resource High throughput screening : methods and protocols, edited by William P. Janzen
High throughput screening : methods and protocols, edited by William P. Janzen
Resource Information
The item High throughput screening : methods and protocols, edited by William P. Janzen represents a specific, individual, material embodiment of a distinct intellectual or artistic creation found in University of Missouri Libraries.This item is available to borrow from 1 library branch.
Resource Information
The item High throughput screening : methods and protocols, edited by William P. Janzen represents a specific, individual, material embodiment of a distinct intellectual or artistic creation found in University of Missouri Libraries.
This item is available to borrow from 1 library branch.
- Summary
- Since its first use in antibiotic research in the 1940s, High Throughput Screening (HTS) has evolved into a major enabling tool and methodology in the discovery of pharmaceutical, chemical, and agricultural compounds. In High Throughput Screening, leading scientists and researchers expert in molecular discovery explain the diverse technologies and key techniques used in HTS and demonstrate how they can be applied generically. Writing to create precisely the introductory guidebook they wished had been available when they started in HTS, these seasoned authors illuminate the HTS process with richly detailed tutorials on the biological techniques involved, the management of compound libraries, and the automation and engineering approaches needed. Extensive discussions provide readers with all those key elements of pharmacology, molecular biology, enzymology, and biochemistry that will ensure the identification of suitable targets and screens, and detail the technology necessary to mine millions of data points for meaningful knowledge. By presenting accounts not only of the basic principles underlying HTS technology, but also real-use cases, High Throughput Screening constitutes a highly practical introduction to HTS, even as it also provides sufficient detail to work more productively in today's lead generation laboratories
- Language
- eng
- Extent
- 1 online resource (ix, 265 pages)
- Contents
-
- Design and implementation of high throughput screening assays / Ricardo Macarrón
- Configuring radioligand receptor binding assays for HTS using scintillation proximity assay technology / John W. Carpenter
- Homogeneous techniques for monitoring receptor-ligand interactions / James S. Marks
- Comparison of SPA, FRET, and FP for kinase assays / Jinzi J. Wu
- Electrochemiluminescence: a technology evaluation and assay reformatting of the Stat6/P578 protein-peptdie interaction / Robert H. Schweitzer
- Cellular assays in HTS / Patricia Johnston
- Compound library management / James A. Chan
- Compound library management: an overview of an automated system / Wilma W. Keighley
- Natural products or not? How to screen for natural products in the emerging HTS paradigm / Susan P. Manly
- Introduction to screening automation / Steven Hamilton
- Unit automation in high throughput screening / Karl C. Menke
- Fully automated screening systems / Seth Cohen
- Management and maintenance of high throughput screening systems / Barbara Hynd
- Isbn
- 9781592591800
- Label
- High throughput screening : methods and protocols
- Title
- High throughput screening
- Title remainder
- methods and protocols
- Statement of responsibility
- edited by William P. Janzen
- Subject
-
- Chemistry, Pharmaceutical
- Drug Evaluation, Preclinical -- methods
- High throughput screening (Drug development)
- High throughput screening (Drug development)
- High throughput screening (Drug development)
- High-Throughput Screening Assays -- methods
- MEDICAL -- Drug Guides
- MEDICAL -- Nursing | Pharmacology
- MEDICAL -- Pharmacology
- MEDICAL -- Pharmacy
- Language
- eng
- Summary
- Since its first use in antibiotic research in the 1940s, High Throughput Screening (HTS) has evolved into a major enabling tool and methodology in the discovery of pharmaceutical, chemical, and agricultural compounds. In High Throughput Screening, leading scientists and researchers expert in molecular discovery explain the diverse technologies and key techniques used in HTS and demonstrate how they can be applied generically. Writing to create precisely the introductory guidebook they wished had been available when they started in HTS, these seasoned authors illuminate the HTS process with richly detailed tutorials on the biological techniques involved, the management of compound libraries, and the automation and engineering approaches needed. Extensive discussions provide readers with all those key elements of pharmacology, molecular biology, enzymology, and biochemistry that will ensure the identification of suitable targets and screens, and detail the technology necessary to mine millions of data points for meaningful knowledge. By presenting accounts not only of the basic principles underlying HTS technology, but also real-use cases, High Throughput Screening constitutes a highly practical introduction to HTS, even as it also provides sufficient detail to work more productively in today's lead generation laboratories
- Cataloging source
- COO
- Dewey number
- 615/.19
- Illustrations
- illustrations
- Index
- index present
- LC call number
- RS419.5
- LC item number
- .H54 2002
- Literary form
- non fiction
- NAL call number
- QH506
- NAL item number
- .M45 v. 190
- Nature of contents
-
- dictionaries
- bibliography
- NLM call number
- QV 771
- NLM item number
- H638 2002
- http://library.link/vocab/relatedWorkOrContributorName
- Janzen, William P
- Series statement
- Methods in molecular biology
- Series volume
- v. 190
- http://library.link/vocab/subjectName
-
- High throughput screening (Drug development)
- Drug Evaluation, Preclinical
- High-Throughput Screening Assays
- Chemistry, Pharmaceutical
- MEDICAL
- MEDICAL
- MEDICAL
- MEDICAL
- High throughput screening (Drug development)
- Label
- High throughput screening : methods and protocols, edited by William P. Janzen
- Bibliography note
- Includes bibliographical references and index
- Carrier category
- online resource
- Carrier category code
-
- cr
- Carrier MARC source
- rdacarrier
- Content category
- text
- Content type code
-
- txt
- Content type MARC source
- rdacontent
- Contents
- Design and implementation of high throughput screening assays / Ricardo Macarrón -- Configuring radioligand receptor binding assays for HTS using scintillation proximity assay technology / John W. Carpenter -- Homogeneous techniques for monitoring receptor-ligand interactions / James S. Marks -- Comparison of SPA, FRET, and FP for kinase assays / Jinzi J. Wu -- Electrochemiluminescence: a technology evaluation and assay reformatting of the Stat6/P578 protein-peptdie interaction / Robert H. Schweitzer -- Cellular assays in HTS / Patricia Johnston -- Compound library management / James A. Chan -- Compound library management: an overview of an automated system / Wilma W. Keighley -- Natural products or not? How to screen for natural products in the emerging HTS paradigm / Susan P. Manly -- Introduction to screening automation / Steven Hamilton -- Unit automation in high throughput screening / Karl C. Menke -- Fully automated screening systems / Seth Cohen -- Management and maintenance of high throughput screening systems / Barbara Hynd
- Control code
- 52434112
- Dimensions
- unknown
- Extent
- 1 online resource (ix, 265 pages)
- Form of item
- online
- Isbn
- 9781592591800
- Media category
- computer
- Media MARC source
- rdamedia
- Media type code
-
- c
- Other physical details
- illustrations (some color).
- Specific material designation
- remote
- System control number
- (OCoLC)52434112
- Label
- High throughput screening : methods and protocols, edited by William P. Janzen
- Bibliography note
- Includes bibliographical references and index
- Carrier category
- online resource
- Carrier category code
-
- cr
- Carrier MARC source
- rdacarrier
- Content category
- text
- Content type code
-
- txt
- Content type MARC source
- rdacontent
- Contents
- Design and implementation of high throughput screening assays / Ricardo Macarrón -- Configuring radioligand receptor binding assays for HTS using scintillation proximity assay technology / John W. Carpenter -- Homogeneous techniques for monitoring receptor-ligand interactions / James S. Marks -- Comparison of SPA, FRET, and FP for kinase assays / Jinzi J. Wu -- Electrochemiluminescence: a technology evaluation and assay reformatting of the Stat6/P578 protein-peptdie interaction / Robert H. Schweitzer -- Cellular assays in HTS / Patricia Johnston -- Compound library management / James A. Chan -- Compound library management: an overview of an automated system / Wilma W. Keighley -- Natural products or not? How to screen for natural products in the emerging HTS paradigm / Susan P. Manly -- Introduction to screening automation / Steven Hamilton -- Unit automation in high throughput screening / Karl C. Menke -- Fully automated screening systems / Seth Cohen -- Management and maintenance of high throughput screening systems / Barbara Hynd
- Control code
- 52434112
- Dimensions
- unknown
- Extent
- 1 online resource (ix, 265 pages)
- Form of item
- online
- Isbn
- 9781592591800
- Media category
- computer
- Media MARC source
- rdamedia
- Media type code
-
- c
- Other physical details
- illustrations (some color).
- Specific material designation
- remote
- System control number
- (OCoLC)52434112
Subject
- Chemistry, Pharmaceutical
- Drug Evaluation, Preclinical -- methods
- High throughput screening (Drug development)
- High throughput screening (Drug development)
- High throughput screening (Drug development)
- High-Throughput Screening Assays -- methods
- MEDICAL -- Drug Guides
- MEDICAL -- Nursing | Pharmacology
- MEDICAL -- Pharmacology
- MEDICAL -- Pharmacy
Member of
Library Links
Embed
Settings
Select options that apply then copy and paste the RDF/HTML data fragment to include in your application
Embed this data in a secure (HTTPS) page:
Layout options:
Include data citation:
<div class="citation" vocab="http://schema.org/"><i class="fa fa-external-link-square fa-fw"></i> Data from <span resource="http://link.library.missouri.edu/portal/High-throughput-screening--methods-and/ISJ1jIJNzZ8/" typeof="Book http://bibfra.me/vocab/lite/Item"><span property="name http://bibfra.me/vocab/lite/label"><a href="http://link.library.missouri.edu/portal/High-throughput-screening--methods-and/ISJ1jIJNzZ8/">High throughput screening : methods and protocols, edited by William P. Janzen</a></span> - <span property="potentialAction" typeOf="OrganizeAction"><span property="agent" typeof="LibrarySystem http://library.link/vocab/LibrarySystem" resource="http://link.library.missouri.edu/"><span property="name http://bibfra.me/vocab/lite/label"><a property="url" href="http://link.library.missouri.edu/">University of Missouri Libraries</a></span></span></span></span></div>
Note: Adjust the width and height settings defined in the RDF/HTML code fragment to best match your requirements
Preview
Cite Data - Experimental
Data Citation of the Item High throughput screening : methods and protocols, edited by William P. Janzen
Copy and paste the following RDF/HTML data fragment to cite this resource
<div class="citation" vocab="http://schema.org/"><i class="fa fa-external-link-square fa-fw"></i> Data from <span resource="http://link.library.missouri.edu/portal/High-throughput-screening--methods-and/ISJ1jIJNzZ8/" typeof="Book http://bibfra.me/vocab/lite/Item"><span property="name http://bibfra.me/vocab/lite/label"><a href="http://link.library.missouri.edu/portal/High-throughput-screening--methods-and/ISJ1jIJNzZ8/">High throughput screening : methods and protocols, edited by William P. Janzen</a></span> - <span property="potentialAction" typeOf="OrganizeAction"><span property="agent" typeof="LibrarySystem http://library.link/vocab/LibrarySystem" resource="http://link.library.missouri.edu/"><span property="name http://bibfra.me/vocab/lite/label"><a property="url" href="http://link.library.missouri.edu/">University of Missouri Libraries</a></span></span></span></span></div>
