Coverart for item
The Resource Immuno Systems Biology : a macroscopic approach for immune cell signaling, by Kumar Selvarajoo

Immuno Systems Biology : a macroscopic approach for immune cell signaling, by Kumar Selvarajoo

Label
Immuno Systems Biology : a macroscopic approach for immune cell signaling
Title
Immuno Systems Biology
Title remainder
a macroscopic approach for immune cell signaling
Statement of responsibility
by Kumar Selvarajoo
Creator
Author
Subject
Language
eng
Summary
Technological advances of modern biology have generated high volumes of 'omics' data. The natural precedence has been to put the complex information together, so that it will lead to spectacular scientific discoveries and medical breakthroughs. In this light, tremendous efforts worldwide are reshaping biological research by integrating with information science. Despite the 'systems biology' efforts, for major illnesses, such as proinflammatory diseases and cancer, there is clear clinical evidence that even the most current therapies, at best, control transient response and subdue to the robust adaptability of the disease state. Hence, there is a need for system-levels understanding of bio-complexity. Kumar Selvarajoo brings attention to fundamental questions governing sophisticated behaviors of the mammalian immune system. To tackle some of the complex issues, the book introduces perturbation-response approach, using the law of physics (mass flow conservation), as a means to interpret the dynamic response of major proinflammatory pathways of the immune and cancer cells. Overall, the book provides an illustrated journey that explains biological cell signaling in simple terms
Member of
Cataloging source
NUI
http://library.link/vocab/creatorName
Selvarajoo, Kumar
Dewey number
610
Illustrations
illustrations
Image bit depth
0
Index
index present
LC call number
QR185.7
Literary form
non fiction
Nature of contents
  • dictionaries
  • bibliography
NLM call number
QU 26.5
Series statement
Systems Biology,
Series volume
3
http://library.link/vocab/subjectName
  • Medicine
  • Immunology
  • Bioinformatics
  • Biological models
  • Cytology
  • Immune System
  • Immunity, Cellular
  • Systems Biology
  • SCIENCE
  • Bioinformatics
  • Biological models
  • Cytology
  • Immunology
  • Medicine
Label
Immuno Systems Biology : a macroscopic approach for immune cell signaling, by Kumar Selvarajoo
Instantiates
Publication
Antecedent source
mixed
Bibliography note
Includes bibliographical references and index
Carrier category
online resource
Carrier category code
cr
Carrier MARC source
rdacarrier
Color
not applicable
Content category
text
Content type code
txt
Content type MARC source
rdacontent
Contents
Preface -- Systems biology of population cell response -- Perturbation-response approach for biological network analysis -- Basics of the mammalian immune system -- Inferring novel features of the TLR4 pathways -- Signaling Flux Redistribution -- Investigating the TLR3 signaling dynamics -- Understanding TNFR1 signaling dynamics -- TRAIL signaling in cancer -- Stochasticity and variability: insights from single cell dynamics -- Investigating single cell stochasticity in TRAIL signaling -- The distinction between single cell and population dynamics -- Finding chaos in biology -- Concluding remarks -- Index
Control code
865495083
Dimensions
unknown
Extent
1 online resource (IX, 146 pages 69 illustrations, 61 illustrations in color.)
File format
multiple file formats
Form of item
online
Isbn
9781306163125
Level of compression
uncompressed
Media category
computer
Media MARC source
rdamedia
Media type code
c
Other control number
10.1007/978-1-4614-7690-0
Other physical details
online resource.
Quality assurance targets
absent
Reformatting quality
access
Specific material designation
remote
System control number
(OCoLC)865495083
Label
Immuno Systems Biology : a macroscopic approach for immune cell signaling, by Kumar Selvarajoo
Publication
Antecedent source
mixed
Bibliography note
Includes bibliographical references and index
Carrier category
online resource
Carrier category code
cr
Carrier MARC source
rdacarrier
Color
not applicable
Content category
text
Content type code
txt
Content type MARC source
rdacontent
Contents
Preface -- Systems biology of population cell response -- Perturbation-response approach for biological network analysis -- Basics of the mammalian immune system -- Inferring novel features of the TLR4 pathways -- Signaling Flux Redistribution -- Investigating the TLR3 signaling dynamics -- Understanding TNFR1 signaling dynamics -- TRAIL signaling in cancer -- Stochasticity and variability: insights from single cell dynamics -- Investigating single cell stochasticity in TRAIL signaling -- The distinction between single cell and population dynamics -- Finding chaos in biology -- Concluding remarks -- Index
Control code
865495083
Dimensions
unknown
Extent
1 online resource (IX, 146 pages 69 illustrations, 61 illustrations in color.)
File format
multiple file formats
Form of item
online
Isbn
9781306163125
Level of compression
uncompressed
Media category
computer
Media MARC source
rdamedia
Media type code
c
Other control number
10.1007/978-1-4614-7690-0
Other physical details
online resource.
Quality assurance targets
absent
Reformatting quality
access
Specific material designation
remote
System control number
(OCoLC)865495083

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