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The Resource In situ polymerizing collagen for the development of 3D printed tissue engineering scaffolds, by Christopher John Glover
In situ polymerizing collagen for the development of 3D printed tissue engineering scaffolds, by Christopher John Glover
Resource Information
The item In situ polymerizing collagen for the development of 3D printed tissue engineering scaffolds, by Christopher John Glover represents a specific, individual, material embodiment of a distinct intellectual or artistic creation found in University of Missouri Libraries.This item is available to borrow from all library branches.
Resource Information
The item In situ polymerizing collagen for the development of 3D printed tissue engineering scaffolds, by Christopher John Glover represents a specific, individual, material embodiment of a distinct intellectual or artistic creation found in University of Missouri Libraries.
This item is available to borrow from all library branches.
- Summary
- Natural materials have been processed and utilized as scaffold materials in the field of tissue engineering for many years. One natural material often utilized is collagen since it is the main structural protein in mammalian tissues and exhibits microstructures suitable for the survival and proliferation of many different cell lineages. However, a common challenge with fibrillized collagen is the difficulty associated with trying to process it into specific three-dimensional designs for the development of scaffolds aimed at regenerating particular tissue types. This project consists of utilizing a custom platform capable of 3D printing in situ polymerizing collagen into user-defined morphologies for the development of 3D collagen-based scaffolds. Various anti-inflammatory compounds such as gold nanoparticles and curcumin were also incorporated into the scaffolds post printing in order to further tailor the cellular responses to the scaffolds. Scanning electron microscopy and neutron activation analysis were performed to verify and quantify the attachment of the gold nanoparticles, respectively. Differential scanning calorimetry was utilized to examine and optimize the stability of the scaffolds after crosslinking. Lastly, water soluble tetrazolium salt and reactive oxygen species assays were performed to assess the biocompatibility of the scaffolds using L929 murine fibroblasts. The results exhibited the viability of the platform to become an effective technique to manufacture and process custom scaffolds for tissue engineering applications
- Language
- eng
- Extent
- 1 online resource (ix, 76 pages)
- Note
-
- Field of study: Biological engineering
- Dr. Sheila Grant, Thesis Supervisor
- Label
- In situ polymerizing collagen for the development of 3D printed tissue engineering scaffolds
- Title
- In situ polymerizing collagen for the development of 3D printed tissue engineering scaffolds
- Statement of responsibility
- by Christopher John Glover
- Language
- eng
- Summary
- Natural materials have been processed and utilized as scaffold materials in the field of tissue engineering for many years. One natural material often utilized is collagen since it is the main structural protein in mammalian tissues and exhibits microstructures suitable for the survival and proliferation of many different cell lineages. However, a common challenge with fibrillized collagen is the difficulty associated with trying to process it into specific three-dimensional designs for the development of scaffolds aimed at regenerating particular tissue types. This project consists of utilizing a custom platform capable of 3D printing in situ polymerizing collagen into user-defined morphologies for the development of 3D collagen-based scaffolds. Various anti-inflammatory compounds such as gold nanoparticles and curcumin were also incorporated into the scaffolds post printing in order to further tailor the cellular responses to the scaffolds. Scanning electron microscopy and neutron activation analysis were performed to verify and quantify the attachment of the gold nanoparticles, respectively. Differential scanning calorimetry was utilized to examine and optimize the stability of the scaffolds after crosslinking. Lastly, water soluble tetrazolium salt and reactive oxygen species assays were performed to assess the biocompatibility of the scaffolds using L929 murine fibroblasts. The results exhibited the viability of the platform to become an effective technique to manufacture and process custom scaffolds for tissue engineering applications
- Cataloging source
- MUU
- http://library.link/vocab/creatorName
- Glover, Christopher John
- Degree
- M.S.
- Dissertation note
- Thesis
- Dissertation year
- 2018.
- Government publication
- government publication of a state province territory dependency etc
- Granting institution
- University of Missouri--Columbia
- Illustrations
- illustrations
- Index
- no index present
- Literary form
- non fiction
- Nature of contents
-
- dictionaries
- bibliography
- theses
- http://library.link/vocab/relatedWorkOrContributorName
- Grant, Sheila Ann
- http://library.link/vocab/subjectName
-
- Tissue engineering
- Tissue scaffolds
- Three-dimensional printing
- Label
- In situ polymerizing collagen for the development of 3D printed tissue engineering scaffolds, by Christopher John Glover
- Note
-
- Field of study: Biological engineering
- Dr. Sheila Grant, Thesis Supervisor
- Bibliography note
- Includes bibliographical references (page 71)
- Carrier category
- online resource
- Carrier category code
-
- cr
- Carrier MARC source
- rdacarrier
- Content category
- text
- Content type code
-
- txt
- Content type MARC source
- rdacontent
- Control code
- 1099182748
- Extent
- 1 online resource (ix, 76 pages)
- Form of item
- online
- Media category
- computer
- Media MARC source
- rdamedia
- Media type code
-
- c
- Other physical details
- illustrations (chiefly color)
- Specific material designation
- remote
- System control number
- (OCoLC)1099182748
- Label
- In situ polymerizing collagen for the development of 3D printed tissue engineering scaffolds, by Christopher John Glover
- Note
-
- Field of study: Biological engineering
- Dr. Sheila Grant, Thesis Supervisor
- Bibliography note
- Includes bibliographical references (page 71)
- Carrier category
- online resource
- Carrier category code
-
- cr
- Carrier MARC source
- rdacarrier
- Content category
- text
- Content type code
-
- txt
- Content type MARC source
- rdacontent
- Control code
- 1099182748
- Extent
- 1 online resource (ix, 76 pages)
- Form of item
- online
- Media category
- computer
- Media MARC source
- rdamedia
- Media type code
-
- c
- Other physical details
- illustrations (chiefly color)
- Specific material designation
- remote
- System control number
- (OCoLC)1099182748
Library Locations
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Engineering Library & Technology CommonsBorrow itW2001 Lafferre Hall, Columbia, MO, 65211, US38.946102 -92.330125
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Fisher Delta Research CenterBorrow it2-64 Agricultural Bldg, Columbia, MO, 65201, US38.958397 -92.303491
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Geological Sciences LibraryBorrow it201 Geological Sciences, Columbia, MO, 65211, US38.947375 -92.329062
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J. Otto Lottes Health Sciences LibraryBorrow it1 Hospital Dr, Columbia, MO, 65201, US38.939544 -92.328377
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Journalism LibraryBorrow it102 Reynolds Jrnlism Institute, Columbia, MO, 65211, US38.947290 -92.328025
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Mathematical Sciences LibraryBorrow it104 Ellis Library, Columbia, MO, 65201, US38.944377 -92.326537
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University ArchivesBorrow itColumbia, MO, 65201, US
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University Archives McAlester AnnexBorrow it703 Lewis Hall, Columbia, MO, 65211, US38.934630 -92.342290
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University of Missouri Libraries DepositoryBorrow it2908 Lemone Blvd, Columbia, MO, 65211, US38.919360 -92.291620
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Zalk Veterinary Medical LibraryBorrow itVeterinary Medicine West, Columbia, MO, 65211, US38.941099 -92.317911
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<div class="citation" vocab="http://schema.org/"><i class="fa fa-external-link-square fa-fw"></i> Data from <span resource="http://link.library.missouri.edu/portal/In-situ-polymerizing-collagen-for-the-development/SkCVk9xfawM/" typeof="Book http://bibfra.me/vocab/lite/Item"><span property="name http://bibfra.me/vocab/lite/label"><a href="http://link.library.missouri.edu/portal/In-situ-polymerizing-collagen-for-the-development/SkCVk9xfawM/">In situ polymerizing collagen for the development of 3D printed tissue engineering scaffolds, by Christopher John Glover</a></span> - <span property="potentialAction" typeOf="OrganizeAction"><span property="agent" typeof="LibrarySystem http://library.link/vocab/LibrarySystem" resource="http://link.library.missouri.edu/"><span property="name http://bibfra.me/vocab/lite/label"><a property="url" href="http://link.library.missouri.edu/">University of Missouri Libraries</a></span></span></span></span></div>