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The Resource In vivo MR techniques in drug discovery and development, edited by Nicolau Beckmann

In vivo MR techniques in drug discovery and development, edited by Nicolau Beckmann

Label
In vivo MR techniques in drug discovery and development
Title
In vivo MR techniques in drug discovery and development
Statement of responsibility
edited by Nicolau Beckmann
Title variation
In vivo magnetic resonance techniques in drug discovery and development
Contributor
Subject
Language
eng
Summary
  • "Imaging technologies are receiving much attention in the pharmaceutical industry because of their potential for accelerating drug discovery and development. Magnetic Resonance (MR) Imaging is one of the principal modalities since it allows anatomical, functional, metabolic, and to a certain extent even target-related information to be gathered in vivo at high resolution, favoring the characterization of a disease state and the corresponding drug intervention. The non-invasiveness of MR strengthens the link between preclinical and clinical pharmaceutical research, contributing to improve the characterization of compound effects in early stages of the discovery process in order to increase the chances of success in later phases of drug development. Edited by a leading researcher in MR technology, with contributions from foremost experts in academia and the pharmaceutical industry, this title illustrates the use of MR techniques throughout the drug discovery and development process, from target identification and validation to clinical studies. Numerous chapters focus on individual disease areas, including neurological, cardiac, and pulmonary disorders, cancer studies, diabetes, arthritis, solid organ transplantation, and stem cell-based therapies, showing that different imaging solutions are needed for specific organs."--Publisher's website
  • " Imaging technologies are receiving much attention in the pharmaceutical industry because of their potential for accelerating drug discovery and development. Magnetic Resonance (MR) Imaging is one of the principal modalities since it allows anatomical, functional, metabolic, and to a certain extent even target-related information to be gathered in vivo at high resolution, favoring the characterization of a disease state and the corresponding drug intervention. The non-invasiveness of MR strengthens the link between preclinical and clinical pharmaceutical research, contributing to improve the characterization of compound effects in early stages of the discovery process in order to increase the chances of success in later phases of drug development. Edited by a leading researcher in MR technology, with contributions from foremost experts in academia and the pharmaceutical industry, this title illustrates the use of MR techniques throughout the drug discovery and development process, from target identification and validation to clinical studies. Numerous chapters focus on individual disease areas, including neurological, cardiac, and pulmonary disorders, cancer studies, diabetes, arthritis, solid organ transplantation, and stem cell-based therapies, showing that different imaging solutions are needed for specific organs."--Publisher's website
  • " Imaging technologies are receiving much attention in the pharmaceutical industry because of their potential for accelerating drug discovery and development. Magnetic Resonance (MR) Imaging is one of the principal modalities since it allows anatomical, functional, metabolic, and to a certain extent even target-related information to be gathered in vivo at high resolution, favoring the characterization of a disease state and the corresponding drug intervention. The non-invasiveness of MR strengthens the link between preclinical and clinical pharmaceutical research, contributing to improve the characterization of compound effects in early stages of the discovery process in order to increase the chances of success in later phases of drug development. Edited by a leading researcher in MR technology, with contributions from foremost experts in academia and the pharmaceutical industry, this title illustrates the use of MR techniques throughout the drug discovery and development process, from target identification and validation to clinical studies. Numerous chapters focus on individual disease areas, including neurological, cardiac, and pulmonary disorders, cancer studies, diabetes, arthritis, solid organ transplantation, and stem cell-based therapies, showing that different imaging solutions are needed for specific organs."--Publisher's website
Cataloging source
DLC
Illustrations
  • illustrations
  • plates
Index
index present
LC call number
RM301.25
LC item number
.I5 2006
Literary form
non fiction
Nature of contents
bibliography
http://library.link/vocab/relatedWorkOrContributorName
Beckmann, Nicolau
http://library.link/vocab/subjectName
  • Drug development
  • Pharmaceutical technology
  • Magnetic resonance imaging
  • Drug Design
  • Magnetic Resonance Imaging
  • Clinical Trials as Topic
  • Drug Evaluation, Preclinical
  • Magnetic Resonance Imaging
  • Technology, Pharmaceutical
Label
In vivo MR techniques in drug discovery and development, edited by Nicolau Beckmann
Instantiates
Publication
Bibliography note
Includes bibliographical references and index
Carrier category
volume
Carrier category code
nc
Carrier MARC source
rdacarrier
Content category
text
Content type code
txt
Content type MARC source
rdacontent
Contents
Ch 1. The drug discovery and development process : a brief overview / Alex Matter -- ch 2. The drug discovery and development process : opportunities and challenges for MR techniques / Nicolau Beckmann and Markus Rudin -- Editorial comments -- ch 3. Imaging as biomarker for decision-making in drug development / Richard Hargreaves and John A. Wagner -- Editorial comments -- ch 4. Design of contrast agents for molecular imaging in vivo / Silvio Aime, Giovanni B. Giovenzana, Dario Longo, and Enzo Terreno -- Editorial comments -- ch 5. Rapid phenotyping of mice with MRI / X. Josette Chen and R. Mark Henkelman -- Editorial comments -- ch 6. Magnetic resonance imaging and spectroscopy in transgenic mice modeling Alzheimer's disease / Thomas Mueggler -- ch 7. Imaging Alzheimer's disease with MRI / Scott A. Small -- ch 8. MRI and MRS in animal models of focal cerebral ischemia / Markus Rudin, Peter R. Allegrini, and Martin Rausch -- ch 9. MRI in clinical studies of stroke / Eric Juettler, Jochen B. Fiebach, and Peter D. Schellinger -- Editorial comments -- ch 10. Pharmacologic magnetic resonance imaging (phMRI) / Bruce G. Jenkins, Ji-Kyung Choi, Joseph B. Mandeville, and Yin-Ching Iris Chen -- ch 11. Brain fMRI in clinical pharmacological studies / Irene Tracey, Petra Schweinhardt, and Chas Bountra -- ch 12. Imaging inflammatory processes of the brain : multiple sclerosis as an example / Martin Rausch, Iris-Katharina Penner, Cedric Berger, and Markus Rudin -- Editorial comments -- ch 13. Functional and molecular magnetic resonance imaging of preclinical cancer models in drug discovery and development / Zaver M. Bhujwalla, Kristine Glunde, Ellen Ackerstaff, Arvind P. Pathak, Barjor Gimi, Noriko Mori, Venu Raman, and Dmitri Artemov -- ch 14. MR for clinical pharmacological studies in cancer / Geoffrey S. Payne, David J. Collins, Elizabeth M. Charles-Edwards, Mounia Beloueche-Babari, and Martin O. Leach -- ch 15. Molecular imaging in cancer therapies of the future / Chrit Moonen
Control code
63117055
Dimensions
27 cm
Extent
568 pages, 12 unnumbered pages of plates
Isbn
9780849330261
Isbn Type
(alk. paper)
Lccn
2006040352
Media category
unmediated
Media MARC source
rdamedia
Media type code
n
Other control number
9780849330261
Other physical details
illustrations (some color)
Label
In vivo MR techniques in drug discovery and development, edited by Nicolau Beckmann
Publication
Bibliography note
Includes bibliographical references and index
Carrier category
volume
Carrier category code
nc
Carrier MARC source
rdacarrier
Content category
text
Content type code
txt
Content type MARC source
rdacontent
Contents
Ch 1. The drug discovery and development process : a brief overview / Alex Matter -- ch 2. The drug discovery and development process : opportunities and challenges for MR techniques / Nicolau Beckmann and Markus Rudin -- Editorial comments -- ch 3. Imaging as biomarker for decision-making in drug development / Richard Hargreaves and John A. Wagner -- Editorial comments -- ch 4. Design of contrast agents for molecular imaging in vivo / Silvio Aime, Giovanni B. Giovenzana, Dario Longo, and Enzo Terreno -- Editorial comments -- ch 5. Rapid phenotyping of mice with MRI / X. Josette Chen and R. Mark Henkelman -- Editorial comments -- ch 6. Magnetic resonance imaging and spectroscopy in transgenic mice modeling Alzheimer's disease / Thomas Mueggler -- ch 7. Imaging Alzheimer's disease with MRI / Scott A. Small -- ch 8. MRI and MRS in animal models of focal cerebral ischemia / Markus Rudin, Peter R. Allegrini, and Martin Rausch -- ch 9. MRI in clinical studies of stroke / Eric Juettler, Jochen B. Fiebach, and Peter D. Schellinger -- Editorial comments -- ch 10. Pharmacologic magnetic resonance imaging (phMRI) / Bruce G. Jenkins, Ji-Kyung Choi, Joseph B. Mandeville, and Yin-Ching Iris Chen -- ch 11. Brain fMRI in clinical pharmacological studies / Irene Tracey, Petra Schweinhardt, and Chas Bountra -- ch 12. Imaging inflammatory processes of the brain : multiple sclerosis as an example / Martin Rausch, Iris-Katharina Penner, Cedric Berger, and Markus Rudin -- Editorial comments -- ch 13. Functional and molecular magnetic resonance imaging of preclinical cancer models in drug discovery and development / Zaver M. Bhujwalla, Kristine Glunde, Ellen Ackerstaff, Arvind P. Pathak, Barjor Gimi, Noriko Mori, Venu Raman, and Dmitri Artemov -- ch 14. MR for clinical pharmacological studies in cancer / Geoffrey S. Payne, David J. Collins, Elizabeth M. Charles-Edwards, Mounia Beloueche-Babari, and Martin O. Leach -- ch 15. Molecular imaging in cancer therapies of the future / Chrit Moonen
Control code
63117055
Dimensions
27 cm
Extent
568 pages, 12 unnumbered pages of plates
Isbn
9780849330261
Isbn Type
(alk. paper)
Lccn
2006040352
Media category
unmediated
Media MARC source
rdamedia
Media type code
n
Other control number
9780849330261
Other physical details
illustrations (some color)

Library Locations

    • J. Otto Lottes Health Sciences LibraryBorrow it
      1 Hospital Dr, Columbia, MO, 65201, US
      38.939544 -92.328377
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