The Resource Investigative study of long-term packaging effects and donor characteristics on acellular dermis scaffolds, by Amanda Kay White, (electronic resource)

Investigative study of long-term packaging effects and donor characteristics on acellular dermis scaffolds, by Amanda Kay White, (electronic resource)

Label
Investigative study of long-term packaging effects and donor characteristics on acellular dermis scaffolds
Title
Investigative study of long-term packaging effects and donor characteristics on acellular dermis scaffolds
Statement of responsibility
by Amanda Kay White
Creator
Contributor
Thesis advisor
Subject
Genre
Language
eng
Summary
Acellular tissue sources have become progressively popular for a variety of tissue engineering and medical applications, such as soft tissue augmentation, skin and vascular grafts, engineered scaffolds, and hernia repair materials. Before tissue sources can be utilized commercially for these practices they usually are decellularized, i.e., have all cellular and nuclear material removed from the extracellular matrix (ECM), and then they are packaged in a convenient, sterile manner for the medical community. While the decellularization techniques have been extensively researched, little is known about the effects of storage or the variability of donor characteristics on the decellularized ECM scaffold. In these studies, acellular dermal grafts stored in ethanol and DI water were analyzed, along with fresh and processed grafts of varying donor characteristics. Dermal grafts from three human donors were subject to varying storage times (t=7 days, 14 days, 30 days, 60 days, and 90 days) to assess the degree of physicochemical changes in the ECM scaffold. Fresh and processed grafts of ten donors with varying backgrounds were used to assess the variability of donor characteristics. Differential scanning calorimetry (DSC), FT-IR spectroscopy, collagenase assay, and tensile testing were utilized to determine ECM variation and physicochemical changes based on storage times and donor variability
Cataloging source
MUU
http://library.link/vocab/creatorName
White, Amanda Kay
Degree
M.S.
Dissertation year
2008.
Granting institution
University of Missouri--Columbia
Illustrations
illustrations
Index
no index present
Literary form
non fiction
Nature of contents
  • dictionaries
  • bibliography
  • theses
http://library.link/vocab/relatedWorkOrContributorName
Grant, Sheila Ann
http://library.link/vocab/subjectName
Tissues
Target audience
specialized
Label
Investigative study of long-term packaging effects and donor characteristics on acellular dermis scaffolds, by Amanda Kay White, (electronic resource)
Instantiates
Publication
Note
  • Title from PDF of title page (University of Missouri--Columbia, viewed on Feb. 19, 2010)
  • The entire thesis text is included in the research.pdf file; the official abstract appears in the short.pdf file; a non-technical public abstract appears in the public.pdf file
  • Dr. Sheila Grant, Thesis Supervisor
Bibliography note
Includes bibliographical references
Carrier category
online resource
Carrier category code
cr
Carrier MARC source
rdacarrier
Content category
text
Content type code
txt
Content type MARC source
rdacontent
Control code
535531481
Extent
1 online resource (x, 113 pages)
Form of item
electronic
Media category
computer
Media MARC source
rdamedia
Media type code
c
Note
MU: Access is limited to the University of Missouri--Columbia only.
Other physical details
illustrations (some color).
Specific material designation
remote
System control number
(OCoLC)535531481
Label
Investigative study of long-term packaging effects and donor characteristics on acellular dermis scaffolds, by Amanda Kay White, (electronic resource)
Publication
Note
  • Title from PDF of title page (University of Missouri--Columbia, viewed on Feb. 19, 2010)
  • The entire thesis text is included in the research.pdf file; the official abstract appears in the short.pdf file; a non-technical public abstract appears in the public.pdf file
  • Dr. Sheila Grant, Thesis Supervisor
Bibliography note
Includes bibliographical references
Carrier category
online resource
Carrier category code
cr
Carrier MARC source
rdacarrier
Content category
text
Content type code
txt
Content type MARC source
rdacontent
Control code
535531481
Extent
1 online resource (x, 113 pages)
Form of item
electronic
Media category
computer
Media MARC source
rdamedia
Media type code
c
Note
MU: Access is limited to the University of Missouri--Columbia only.
Other physical details
illustrations (some color).
Specific material designation
remote
System control number
(OCoLC)535531481

Library Locations

    • Ellis LibraryBorrow it
      1020 Lowry Street, Columbia, MO, 65201, US
      38.944491 -92.326012
    • Engineering Library & Technology CommonsBorrow it
      W2001 Lafferre Hall, Columbia, MO, 65211, US
      38.946102 -92.330125
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