Coverart for item
The Resource Mass spectrometry of proteins and peptides, edited by John R. Chapman

Mass spectrometry of proteins and peptides, edited by John R. Chapman

Label
Mass spectrometry of proteins and peptides
Title
Mass spectrometry of proteins and peptides
Statement of responsibility
edited by John R. Chapman
Contributor
Subject
Genre
Language
eng
Summary
New types of mass spectrometric instrumentation and new ionization techniques have dramatically extended the applicability of mass spectrometry to the analysis of proteins and peptides. In Mass Spectrometry of Proteins and Peptides, John R. Chapman recreates the success of his earlier acclaimed book (Protein and Peptide Analysis by Mass Spectrometry, 1996) with a major new collection of cutting-edge methods in this area. Contributed by well-established investigators, each chapter provides background information before guiding the researcher step-by-step through the experimental process, with detailed instructions to help assure experimental success. The applications covered range widely and include protein sequencing, higher-order structure determination, epitope mapping, kinetics, quantitation, glycosylation analysis, and bacterial typing. Authoritative and eminently practical, Mass Spectrometry of Proteins and Peptides demonstrates the full scope of this versatile analytical technique. All protein chemists and biochemists, as well as bioanalytical scientists, who want to exploit these powerful methods in their work, will find this book indispensable
Member of
Cataloging source
COO
Dewey number
572/.633
Illustrations
illustrations
Index
index present
Language note
English
LC call number
QP551
LC item number
.M33 2000
Literary form
non fiction
NAL call number
QH506
NAL item number
.M45 v. 146
Nature of contents
  • dictionaries
  • bibliography
NLM call number
  • W1
  • QU 25
NLM item number
  • ME9616J v.146 2000
  • C165 2000
http://library.link/vocab/relatedWorkOrContributorName
Chapman, J. R
Series statement
Methods in molecular biology
Series volume
146
http://library.link/vocab/subjectName
  • Proteins
  • Peptides
  • Amino acid sequence
  • Mass spectrometry
  • Proteins
  • Mass Spectrometry
  • Peptides
  • Chemistry
  • Human Anatomy & Physiology
  • Biology
  • Health & Biological Sciences
  • Physical Sciences & Mathematics
  • Animal Biochemistry
  • Biology
  • Biochemistry
  • SCIENCE
  • Amino acid sequence
  • Mass spectrometry
  • Peptides
  • Proteins
  • Massaspectrometrie
  • Eiwitten
  • Peptiden
  • Sequenties
  • Wetenschappelijke technieken
Label
Mass spectrometry of proteins and peptides, edited by John R. Chapman
Instantiates
Publication
Bibliography note
Includes bibliographical references and index
Carrier category
online resource
Carrier category code
  • cr
Carrier MARC source
rdacarrier
Content category
text
Content type code
  • txt
Content type MARC source
rdacontent
Contents
De Novo peptide sequencing by nanoelecrospray tandem mass spectrometry using triple quadrupole and quadrupole/time-of-flight instruments -- Direct analysis of proteins in mixtures: application to protein complexes -- Characterizaton of a mutant recombinant S100 protein using electrospray ionization mass spectrometry -- Searching sequence databases via De Novo peptide sequencing by tandem mass spectrometry -- Signature peptides: from analytical chemistry to functional genomics -- Ivestigating the higher order structure of proteins: hydrogen exchange, proteolytic fragmentation, and mass spectrometry -- Probing protein surface topology by chemical surface labeling, crosslinking, and mass spectrometry -- Secondary structure of peptide ions in the gas phase evaluated by MIKE spectrometry: relevance to native conformations -- Preparation and mass spectrometric analysis of S-nitrosohemoglobin -- Multiple and subsequent MALDI-MS on-target chemical reactions for the characterization of dislfide bonds and primary structures of proteins -- Epitope mapping by a combination of epitope excision and MALDI-MS -- Identification of active site residues in glycosidases by use of tandem mass spectrometry -- Probing protein-protein interactions with mass spectrometry -- Studies of noncovalent complexes in an electrospray ionization/time-of-flight mass spectrometer -- Kinetic analysis of enzymatic and nonenzymatic degradation of peptides by MALDI-TOFMS -- Characterization of protein glycosylation by MALDI-TOFMS -- Positive and negative labeling of human proinsulin, insulin and C-peptide with stable isotopes: new tools for in vivo pharmacokinetic and metabolic studies -- Identification of snake species by toxin mass fingerprinting of their venoms -- Mass spectrometric characterization of the [beta]-subunit of human chorionic gonadotropin -- Analysis of gluten in foods by MALD-TOFMS -- Quantitation of nucleotidyl cyclase and cyclic nucleotide-sensitive protein kinase activities by fast-atom bombardment mass spectrometry: a paradigm for multiple component monitoring in enzyme incubations by quantitative mass spectrometry -- Influence of salts, buffers, detergents, solvents, and matrices on MALDI-MS protein analysis in complex mixtures -- Sample preparation techniques for peptides and proteins analyzed by MALDI-MS -- Analysis of hydrophobic proteins and peptides by mass spectrometry -- Analysis of proteins and peptides directly from biological fluids by immunoprecipitation/mass spectrometry -- Detection of molecular determinants in complex biological systems using MALDI-TOF affinity mass spectrometry -- Rapid identification of bacteria based on spectral patterns using MALDI-TOFMS -- Appendices
Control code
619243032
Dimensions
unknown
Extent
1 online resource (xiv, 538 pages)
Form of item
online
Isbn
9781592590452
Media category
computer
Media MARC source
rdamedia
Media type code
  • c
Other physical details
illustrations.
Specific material designation
remote
System control number
(OCoLC)619243032
Label
Mass spectrometry of proteins and peptides, edited by John R. Chapman
Publication
Bibliography note
Includes bibliographical references and index
Carrier category
online resource
Carrier category code
  • cr
Carrier MARC source
rdacarrier
Content category
text
Content type code
  • txt
Content type MARC source
rdacontent
Contents
De Novo peptide sequencing by nanoelecrospray tandem mass spectrometry using triple quadrupole and quadrupole/time-of-flight instruments -- Direct analysis of proteins in mixtures: application to protein complexes -- Characterizaton of a mutant recombinant S100 protein using electrospray ionization mass spectrometry -- Searching sequence databases via De Novo peptide sequencing by tandem mass spectrometry -- Signature peptides: from analytical chemistry to functional genomics -- Ivestigating the higher order structure of proteins: hydrogen exchange, proteolytic fragmentation, and mass spectrometry -- Probing protein surface topology by chemical surface labeling, crosslinking, and mass spectrometry -- Secondary structure of peptide ions in the gas phase evaluated by MIKE spectrometry: relevance to native conformations -- Preparation and mass spectrometric analysis of S-nitrosohemoglobin -- Multiple and subsequent MALDI-MS on-target chemical reactions for the characterization of dislfide bonds and primary structures of proteins -- Epitope mapping by a combination of epitope excision and MALDI-MS -- Identification of active site residues in glycosidases by use of tandem mass spectrometry -- Probing protein-protein interactions with mass spectrometry -- Studies of noncovalent complexes in an electrospray ionization/time-of-flight mass spectrometer -- Kinetic analysis of enzymatic and nonenzymatic degradation of peptides by MALDI-TOFMS -- Characterization of protein glycosylation by MALDI-TOFMS -- Positive and negative labeling of human proinsulin, insulin and C-peptide with stable isotopes: new tools for in vivo pharmacokinetic and metabolic studies -- Identification of snake species by toxin mass fingerprinting of their venoms -- Mass spectrometric characterization of the [beta]-subunit of human chorionic gonadotropin -- Analysis of gluten in foods by MALD-TOFMS -- Quantitation of nucleotidyl cyclase and cyclic nucleotide-sensitive protein kinase activities by fast-atom bombardment mass spectrometry: a paradigm for multiple component monitoring in enzyme incubations by quantitative mass spectrometry -- Influence of salts, buffers, detergents, solvents, and matrices on MALDI-MS protein analysis in complex mixtures -- Sample preparation techniques for peptides and proteins analyzed by MALDI-MS -- Analysis of hydrophobic proteins and peptides by mass spectrometry -- Analysis of proteins and peptides directly from biological fluids by immunoprecipitation/mass spectrometry -- Detection of molecular determinants in complex biological systems using MALDI-TOF affinity mass spectrometry -- Rapid identification of bacteria based on spectral patterns using MALDI-TOFMS -- Appendices
Control code
619243032
Dimensions
unknown
Extent
1 online resource (xiv, 538 pages)
Form of item
online
Isbn
9781592590452
Media category
computer
Media MARC source
rdamedia
Media type code
  • c
Other physical details
illustrations.
Specific material designation
remote
System control number
(OCoLC)619243032

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