Coverart for item
The Resource Metabolic Flux Analysis : Methods and Protocols, edited by Jens O. Krömer, Lars K. Nielsen, Lars M. Blank

Metabolic Flux Analysis : Methods and Protocols, edited by Jens O. Krömer, Lars K. Nielsen, Lars M. Blank

Label
Metabolic Flux Analysis : Methods and Protocols
Title
Metabolic Flux Analysis
Title remainder
Methods and Protocols
Statement of responsibility
edited by Jens O. Krömer, Lars K. Nielsen, Lars M. Blank
Contributor
Editor
Subject
Genre
Language
eng
Summary
"This book is dedicated to Metabolic Flux Analysis in systems that can be studied under metabolic steady-state or pseudo-steady-state conditions, also called stationary approaches. Under these conditions the change of intracellular metabolite concentrations (CMET) as a function of the stoichiometric matrix S and the flux vector v can be approximated to zero. This approximation converts the equations system from a differential to a linear one and greatly simplifies its solution. We hope that this book will open the field of metabolic flux analysis to a wider scientific community by providing helpful tricks to those who want to start a new flux analysis project but are overwhelmed by the complexity of the approach. We tried to break it up into manageable bits of information that can be implemented step by step following the methods chapters provided. The overview chapters are there to explain the necessary basics to get started and also to review what has been achieved within a few model organisms."--Preface, page vi
Member of
Cataloging source
GW5XE
Dewey number
570
Illustrations
illustrations
Index
index present
LC call number
  • QH521
  • QH324.9.M4
LC item number
  • .M477 2014
  • M477 2014
Literary form
non fiction
Nature of contents
  • dictionaries
  • bibliography
NLM call number
  • W1 ME9616J
  • QY 25
NLM item number
v.1191 2014
http://library.link/vocab/relatedWorkOrContributorName
  • Krömer, Jens O.
  • Nielsen, Lars K.
  • Blank, Lars M.
Series statement
Methods in Molecular Biology,
Series volume
Volume 1191
http://library.link/vocab/subjectName
  • Metabolites
  • Systems biology
  • Metabolic Flux Analysis
  • Metabolites
  • Systems biology
  • Biology
Label
Metabolic Flux Analysis : Methods and Protocols, edited by Jens O. Krömer, Lars K. Nielsen, Lars M. Blank
Instantiates
Publication
Copyright
Antecedent source
unknown
Bibliography note
Includes bibliographical references and index
Carrier category
online resource
Carrier category code
  • cr
Carrier MARC source
rdacarrier
Color
multicolored
Content category
text
Content type code
  • txt
Content type MARC source
rdacontent
Contents
  • PART II.
  • THERMODYNAMICS: A STEP BEYOND MFA
  • 3.
  • Constraining the Flux Space Using Thermodynamics and Integration of Metabolomics Data
  • Keng Cher Soh and Vassily Hatzimanikatis
  • 4.
  • NExT: Integration of Thermodynamic Constraints and Metabolomics Data into a Metabolic Network
  • Verónica Sofía Martínez and Lars K. Nielsen
  • PART III.
  • EXPERIMENTS: DESIGN CONSIDERATIONS, FERMENTATION, ANALYTICS
  • PART I.
  • 5.
  • Customization of 13C-MFA Strategy According to Cell Culture System
  • Lake-Ee Quek and Lars K. Nielsen
  • 6.
  • Quantitative Metabolomics Using ID-MS
  • S. Aljoscha Wahl, Reza Maleki Seifar, Angela ten Pierick, Cor Ras, Jan C. van Dam, Joseph J. Heijnen, and Walter M. van Gulik
  • 7.
  • Determining the Biomass Composition of a Sponge Holobiont for Flux Analysis
  • Jabin Watson, Bernard Degnan, Sandie Degnan, and Jens O. Krömer
  • 8.
  • MODELS: STOICHIOMETRY, NETWORK GENERATION
  • Successful Downsizing for High-Throughput 13C-MFA Applications
  • Birgitta E. Ebert and Lars M. Blank
  • 9.
  • Labelling Analysis for 13C MFA Using NMR Spectroscopy
  • Paula Jouhten and Hannu Maaheimo
  • 10.
  • GC-MS-Based 13C Metabolic Flux Analysis
  • Judith Becker and Christoph Wittmann
  • 11.
  • Dynamic Analysis of CO2 Labeling and Cell Respiration Using Membrane-Inlet Mass Spectrometry
  • 1.
  • Tae Hoon Yang
  • PART IV.
  • 13C FLUXOMICS DATA PROCESSING
  • 12.
  • Correction of MS Data for Naturally Occurring Isotopes in Isotope Labelling Experiments
  • Pierre Millard, Fabien Letisse, Serguei Sokol, and Jean-Charles Portais
  • 13.
  • Steady-State 13C Fluxomics Using OpenFLUX
  • Lake-Ee Quek and Lars K. Nielsen
  • 14.
  • Stoichiometric Modelling of Microbial Metabolism
  • Flux Visualization Using VANTED/FluxMap
  • Christian Krach, Astrid Junker, Hendrik Rohn, Falk Schreiber, and Björn H. Junker
  • PART V.
  • EXAMPLES
  • 15.
  • Metabolic Flux Analysis for Escherichia coli by Flux Balance Analysis
  • Yu Matsuoka and Kazuyuki Shimizu
  • 16.
  • 13C-Metabolic Flux Analysis for Escherichia coli
  • Yu Matsuoka and Kazuyuki Shimizu
  • Lars Kuepfer
  • 17.
  • 13C-Based Metabolic Flux Analysis of Recombinant Pichia pastoris
  • Pau Ferrer and Joan Albiol
  • 2.
  • Tapping the Wealth of Microbial Data in High-Throughput Metabolic Model Reconstruction
  • Ric Colasanti, Janaka N. Edirisinghe, Tahmineh Khazaei, José P. Faria, Sam Seaver, Fangfang Xia, and Christopher Henry
Control code
891059613
Dimensions
unknown
Extent
1 online resource (xii, 316 pages)
File format
unknown
Form of item
online
Isbn
9781493911707
Level of compression
unknown
Media category
computer
Media MARC source
rdamedia
Media type code
  • c
Other control number
10.1007/978-1-4939-1170-7
Other physical details
illustrations (some color).
Quality assurance targets
not applicable
Reformatting quality
unknown
Sound
unknown sound
Specific material designation
remote
System control number
(OCoLC)891059613
Label
Metabolic Flux Analysis : Methods and Protocols, edited by Jens O. Krömer, Lars K. Nielsen, Lars M. Blank
Publication
Copyright
Antecedent source
unknown
Bibliography note
Includes bibliographical references and index
Carrier category
online resource
Carrier category code
  • cr
Carrier MARC source
rdacarrier
Color
multicolored
Content category
text
Content type code
  • txt
Content type MARC source
rdacontent
Contents
  • PART II.
  • THERMODYNAMICS: A STEP BEYOND MFA
  • 3.
  • Constraining the Flux Space Using Thermodynamics and Integration of Metabolomics Data
  • Keng Cher Soh and Vassily Hatzimanikatis
  • 4.
  • NExT: Integration of Thermodynamic Constraints and Metabolomics Data into a Metabolic Network
  • Verónica Sofía Martínez and Lars K. Nielsen
  • PART III.
  • EXPERIMENTS: DESIGN CONSIDERATIONS, FERMENTATION, ANALYTICS
  • PART I.
  • 5.
  • Customization of 13C-MFA Strategy According to Cell Culture System
  • Lake-Ee Quek and Lars K. Nielsen
  • 6.
  • Quantitative Metabolomics Using ID-MS
  • S. Aljoscha Wahl, Reza Maleki Seifar, Angela ten Pierick, Cor Ras, Jan C. van Dam, Joseph J. Heijnen, and Walter M. van Gulik
  • 7.
  • Determining the Biomass Composition of a Sponge Holobiont for Flux Analysis
  • Jabin Watson, Bernard Degnan, Sandie Degnan, and Jens O. Krömer
  • 8.
  • MODELS: STOICHIOMETRY, NETWORK GENERATION
  • Successful Downsizing for High-Throughput 13C-MFA Applications
  • Birgitta E. Ebert and Lars M. Blank
  • 9.
  • Labelling Analysis for 13C MFA Using NMR Spectroscopy
  • Paula Jouhten and Hannu Maaheimo
  • 10.
  • GC-MS-Based 13C Metabolic Flux Analysis
  • Judith Becker and Christoph Wittmann
  • 11.
  • Dynamic Analysis of CO2 Labeling and Cell Respiration Using Membrane-Inlet Mass Spectrometry
  • 1.
  • Tae Hoon Yang
  • PART IV.
  • 13C FLUXOMICS DATA PROCESSING
  • 12.
  • Correction of MS Data for Naturally Occurring Isotopes in Isotope Labelling Experiments
  • Pierre Millard, Fabien Letisse, Serguei Sokol, and Jean-Charles Portais
  • 13.
  • Steady-State 13C Fluxomics Using OpenFLUX
  • Lake-Ee Quek and Lars K. Nielsen
  • 14.
  • Stoichiometric Modelling of Microbial Metabolism
  • Flux Visualization Using VANTED/FluxMap
  • Christian Krach, Astrid Junker, Hendrik Rohn, Falk Schreiber, and Björn H. Junker
  • PART V.
  • EXAMPLES
  • 15.
  • Metabolic Flux Analysis for Escherichia coli by Flux Balance Analysis
  • Yu Matsuoka and Kazuyuki Shimizu
  • 16.
  • 13C-Metabolic Flux Analysis for Escherichia coli
  • Yu Matsuoka and Kazuyuki Shimizu
  • Lars Kuepfer
  • 17.
  • 13C-Based Metabolic Flux Analysis of Recombinant Pichia pastoris
  • Pau Ferrer and Joan Albiol
  • 2.
  • Tapping the Wealth of Microbial Data in High-Throughput Metabolic Model Reconstruction
  • Ric Colasanti, Janaka N. Edirisinghe, Tahmineh Khazaei, José P. Faria, Sam Seaver, Fangfang Xia, and Christopher Henry
Control code
891059613
Dimensions
unknown
Extent
1 online resource (xii, 316 pages)
File format
unknown
Form of item
online
Isbn
9781493911707
Level of compression
unknown
Media category
computer
Media MARC source
rdamedia
Media type code
  • c
Other control number
10.1007/978-1-4939-1170-7
Other physical details
illustrations (some color).
Quality assurance targets
not applicable
Reformatting quality
unknown
Sound
unknown sound
Specific material designation
remote
System control number
(OCoLC)891059613

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      38.944491 -92.326012
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