The Resource Mitochondrial replacement techniques : ethical, social, and policy considerations, Committee on the Ethical and Social Policy Considerations of Novel Techniques for Prevention of Maternal Transmission of Mitochondrial DNA Diseases, Board on Health Sciences Policy, Institute of Medicine ; Anne Claiborne, Rebecca English, and Jeffrey Kahn, editors ; National Academies of Sciences, Engineering, Medicine

Mitochondrial replacement techniques : ethical, social, and policy considerations, Committee on the Ethical and Social Policy Considerations of Novel Techniques for Prevention of Maternal Transmission of Mitochondrial DNA Diseases, Board on Health Sciences Policy, Institute of Medicine ; Anne Claiborne, Rebecca English, and Jeffrey Kahn, editors ; National Academies of Sciences, Engineering, Medicine

Label
Mitochondrial replacement techniques : ethical, social, and policy considerations
Title
Mitochondrial replacement techniques
Title remainder
ethical, social, and policy considerations
Statement of responsibility
Committee on the Ethical and Social Policy Considerations of Novel Techniques for Prevention of Maternal Transmission of Mitochondrial DNA Diseases, Board on Health Sciences Policy, Institute of Medicine ; Anne Claiborne, Rebecca English, and Jeffrey Kahn, editors ; National Academies of Sciences, Engineering, Medicine
Creator
Contributor
Author
Editor
Subject
Language
eng
Summary
"Mitochondrial replacement techniques (MRTs) are designed to prevent the transmission of mitochondrial DNA (mtDNA) diseases from mother to child. While MRTs, if effective, could satisfy a desire of women seeking to have a genetically related child without the risk of passing on mtDNA disease, the technique raises significant ethical and social issues. It would create offspring who have genetic material from two women, something never sanctioned in humans, and would create mitochondrial changes that could be heritable (in female offspring), and therefore passed on in perpetuity. The manipulation would be performed on eggs or embryos, would affect every cell of the resulting individual, and once carried out this genetic manipulation is not reversible. Mitochondrial Replacement Techniques considers the implications of manipulating mitochondrial content both in children born to women as a result of participating in these studies and in descendants of any female offspring. This study examines the ethical and social issues related to MRTs, outlines principles that would provide a framework and foundation for oversight of MRTs, and develops recommendations to inform the Food and Drug Administrations consideration of investigational new drug applications"--Publisher's description
Cataloging source
MMU
Dewey number
616.6/92
Illustrations
illustrations
Index
no index present
LC call number
RG133.5
Literary form
non fiction
Nature of contents
  • dictionaries
  • bibliography
NLM call number
WQ 208
http://bibfra.me/vocab/lite/organizationName
Institute of Medicine (U.S.)
http://library.link/vocab/relatedWorkOrContributorName
  • Claiborne, Anne B.
  • English, Rebecca A.
  • Kahn, Jeffrey P.
http://library.link/vocab/subjectName
  • Reproductive technology
  • Reproductive technology
  • Mitochondrial DNA
  • Mitochondrial pathology
  • Medical ethics
  • United States
  • Mitochondrial Replacement Therapy
  • Mitochondrial Replacement Therapy
  • Ethics, Medical
  • Mitochondrial Diseases
  • Government Regulation
  • Reproductive Techniques, Assisted
  • United States
Label
Mitochondrial replacement techniques : ethical, social, and policy considerations, Committee on the Ethical and Social Policy Considerations of Novel Techniques for Prevention of Maternal Transmission of Mitochondrial DNA Diseases, Board on Health Sciences Policy, Institute of Medicine ; Anne Claiborne, Rebecca English, and Jeffrey Kahn, editors ; National Academies of Sciences, Engineering, Medicine
Instantiates
Publication
Copyright
Bibliography note
Includes bibliographical references
Carrier category
online resource
Carrier category code
cr
Carrier MARC source
rdacarrier
Content category
text
Content type code
txt
Content type MARC source
rdacontent
Contents
Introduction -- Science and policy context -- Do ethical, social, and policy considerations preclude MRT? -- Regulation and oversight of MRT in humans
Control code
945556529
Extent
1 online resource (xvi, 184 pages)
Form of item
online
Media category
  • still image
  • computer
Media MARC source
  • rdacontent
  • rdamedia
Media type code
  • sti
  • c
Other physical details
color illustrations
Specific material designation
remote
System control number
(OCoLC)945556529
Label
Mitochondrial replacement techniques : ethical, social, and policy considerations, Committee on the Ethical and Social Policy Considerations of Novel Techniques for Prevention of Maternal Transmission of Mitochondrial DNA Diseases, Board on Health Sciences Policy, Institute of Medicine ; Anne Claiborne, Rebecca English, and Jeffrey Kahn, editors ; National Academies of Sciences, Engineering, Medicine
Publication
Copyright
Bibliography note
Includes bibliographical references
Carrier category
online resource
Carrier category code
cr
Carrier MARC source
rdacarrier
Content category
text
Content type code
txt
Content type MARC source
rdacontent
Contents
Introduction -- Science and policy context -- Do ethical, social, and policy considerations preclude MRT? -- Regulation and oversight of MRT in humans
Control code
945556529
Extent
1 online resource (xvi, 184 pages)
Form of item
online
Media category
  • still image
  • computer
Media MARC source
  • rdacontent
  • rdamedia
Media type code
  • sti
  • c
Other physical details
color illustrations
Specific material designation
remote
System control number
(OCoLC)945556529

Library Locations

  • Ellis LibraryBorrow it
    1020 Lowry Street, Columbia, MO, 65201, US
    38.944491 -92.326012
  • Engineering Library & Technology CommonsBorrow it
    W2001 Lafferre Hall, Columbia, MO, 65211, US
    38.946102 -92.330125
  • Fisher Delta Research CenterBorrow it
    2-64 Agricultural Bldg, Columbia, MO, 65201, US
    38.958397 -92.303491
  • Geological Sciences LibraryBorrow it
    201 Geological Sciences, Columbia, MO, 65211, US
    38.947375 -92.329062
  • J. Otto Lottes Health Sciences LibraryBorrow it
    1 Hospital Dr, Columbia, MO, 65201, US
    38.939544 -92.328377
  • Journalism LibraryBorrow it
    102 Reynolds Jrnlism Institute, Columbia, MO, 65211, US
    38.947290 -92.328025
  • Mathematical Sciences LibraryBorrow it
    104 Ellis Library, Columbia, MO, 65201, US
    38.944377 -92.326537
  • University ArchivesBorrow it
    Columbia, MO, 65201, US
  • University Archives McAlester AnnexBorrow it
    703 Lewis Hall, Columbia, MO, 65211, US
    38.934630 -92.342290
  • University of Missouri Libraries DepositoryBorrow it
    2908 Lemone Blvd, Columbia, MO, 65211, US
    38.919360 -92.291620
  • Zalk Veterinary Medical LibraryBorrow it
    Veterinary Medicine West, Columbia, MO, 65211, US
    38.941099 -92.317911
Processing Feedback ...