The Resource Modeling of phototransduction in vision systems, by Lei Lu, (electronic resource)

Modeling of phototransduction in vision systems, by Lei Lu, (electronic resource)

Label
Modeling of phototransduction in vision systems
Title
Modeling of phototransduction in vision systems
Statement of responsibility
by Lei Lu
Creator
Contributor
Thesis advisor
Subject
Genre
Language
eng
Summary
To improve the usefulness of the electroretinogram (ERG) in identifying the sites and mechanisms of adaptation, development and disease processes, a quantitative model was developed based on the biochemical reaction kinetics in the phototransduction cascade and experimental data. A set of differential equations were derived to predict the electrical response of photoreceptors to light and system identification was employed to determine the model parameters. When applied to wild-type and retina-damaged mice, the proposed model effectively described the ERG a-wave over a range of light intensities and different stimulus patterns. From the model parameters, the retina-damaged subjects could be differentiated from the normal ones. It is anticipated that this model could help detect changes in the phototransduction process and enhance the utility of ERG in the clinic. It also provides insights into dynamics of the vision system
Cataloging source
MUU
http://library.link/vocab/creatorDate
1968-
http://library.link/vocab/creatorName
Lu, Lei
Degree
M.S.
Dissertation year
2007.
Granting institution
University of Missouri-Columbia
Illustrations
illustrations
Index
no index present
Literary form
non fiction
Nature of contents
  • dictionaries
  • bibliography
  • theses
http://library.link/vocab/relatedWorkOrContributorDate
1958-
http://library.link/vocab/relatedWorkOrContributorName
Tan, Jinglu
http://library.link/vocab/subjectName
  • Electroretinography
  • Eye
  • Cellular signal transduction
  • Neural transmission
Target audience
specialized
Label
Modeling of phototransduction in vision systems, by Lei Lu, (electronic resource)
Instantiates
Publication
Note
  • The entire dissertation/thesis text is included in the research.pdf file; the official abstract appears in the short.pdf file (which also appears in the research.pdf); a non-technical general description, or public abstract, appears in the public.pdf file
  • Title from title screen of research.pdf file (viewed on April 1, 2008)
Bibliography note
Includes bibliographical references
Carrier category
online resource
Carrier category code
cr
Carrier MARC source
rdacarrier
Color
mixed
Content category
text
Content type code
txt
Content type MARC source
rdacontent
Control code
216928820
Dimensions
unknown
Form of item
electronic
Media category
computer
Media MARC source
rdamedia
Media type code
c
Specific material designation
remote
System control number
(OCoLC)216928820
System details
Mode of access: World Wide Web
Label
Modeling of phototransduction in vision systems, by Lei Lu, (electronic resource)
Publication
Note
  • The entire dissertation/thesis text is included in the research.pdf file; the official abstract appears in the short.pdf file (which also appears in the research.pdf); a non-technical general description, or public abstract, appears in the public.pdf file
  • Title from title screen of research.pdf file (viewed on April 1, 2008)
Bibliography note
Includes bibliographical references
Carrier category
online resource
Carrier category code
cr
Carrier MARC source
rdacarrier
Color
mixed
Content category
text
Content type code
txt
Content type MARC source
rdacontent
Control code
216928820
Dimensions
unknown
Form of item
electronic
Media category
computer
Media MARC source
rdamedia
Media type code
c
Specific material designation
remote
System control number
(OCoLC)216928820
System details
Mode of access: World Wide Web

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