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The Resource Modulators, mediators, and specifiers in brain function : interactions of neuropeptides, cyclic nucleotides, and phosphorproteins in mechanisms underlying neuronal activity, behavior, and neuropsychiatric disorders, edited by Y. H. Ehrlich [and others]

Modulators, mediators, and specifiers in brain function : interactions of neuropeptides, cyclic nucleotides, and phosphorproteins in mechanisms underlying neuronal activity, behavior, and neuropsychiatric disorders, edited by Y. H. Ehrlich [and others]

Label
Modulators, mediators, and specifiers in brain function : interactions of neuropeptides, cyclic nucleotides, and phosphorproteins in mechanisms underlying neuronal activity, behavior, and neuropsychiatric disorders
Title
Modulators, mediators, and specifiers in brain function
Title remainder
interactions of neuropeptides, cyclic nucleotides, and phosphorproteins in mechanisms underlying neuronal activity, behavior, and neuropsychiatric disorders
Statement of responsibility
edited by Y. H. Ehrlich [and others]
Contributor
Subject
Genre
Language
eng
Summary
This volume is an outcome of a satellite symposium held on November 4th and 5th, 1978, at the Missouri Institute of Psychiatry, St. Louis, in conjunction with the eighth annual meeting of the Society for Neuroscience. The symposium was planned and organized in order to provide information which may help in narrowing the gap between data obtained by investigators engaged in basic neuroscience research and the clinical implications of these findings. The empirical introduction of psychopharmacological agents to clinical use in the early 1950's facilitated investigations aimed at elucidating basic mechanisms that underlie brain function and behavior. In recent years, we have witnessed developments in the opposite direction; discoveries in the laboratories of researchers in the basic neurosciences have produced new approaches in treatment of the mentally ill patient. Receptors, the existence of which had heretofore been largely based on hypotheses, have been shown as entities which can be identified, isolated, and studied in the test tube. The complexity of receptor function has become apparent. In addition to containing binding sites for a specific neurotransmitter, the receptor exists as part of a macromolecular complex the activity of which may be modulated by neuroactive peptides and mediated by the generation of cyclic nucleotides. The cyclic nucleotides appear to exert their physiological effects by regulating protein phosphorylation-dephosphorylation cycles. Different specific phosphoproteins control metabolic events in the cell interior. In addition, membrane-bound phosphoproteins may play a role in the regulation of receptor function, and this process may be regulated by neuropeptides. Thus, the receptor, when studied as a functional entity, may be analyzed as a multiplicity of interactions between binding sites, transmitters, modulators, mediators and specifiers in the nervous system. This book is concerned with recent studies which have sought to define the roles of neuropeptides, cyclic nucleotides, and phosphoproteins in neural function. These subjects are introduced in the first section of the volume, their potential mechanisms of action are discussed in a second section, and a third section is devoted to studies on the relevance of these systems to the etiology and treatment of some neuropsychiatric disorders. The experimental approaches described by the authors include physiological, neurochemical, pharmacological, behavioral, and clinical investigations, and clearly demonstrate the multi-disciplinary nature of current research in neuroscience
Member of
Cataloging source
DLC
Index
no index present
Literary form
non fiction
http://library.link/vocab/relatedWorkOrContributorName
  • Ehrlich, Yigal H
  • Society for Neuroscience
  • Missouri Institute of Psychiatry
Series statement
Advances in experimental medicine and biology
Series volume
v. 116
http://library.link/vocab/subjectName
  • Brain chemistry
  • Neuropeptides
  • Neural receptors
  • Cyclic nucleotides
  • Neuropsychiatry
  • Brain Chemistry
  • Brain
  • Nucleotides, Cyclic
  • Peptides
  • Phosphoproteins
  • Psychopharmacology
  • Receptors, Neurotransmitter
Label
Modulators, mediators, and specifiers in brain function : interactions of neuropeptides, cyclic nucleotides, and phosphorproteins in mechanisms underlying neuronal activity, behavior, and neuropsychiatric disorders, edited by Y. H. Ehrlich [and others]
Instantiates
Publication
Note
  • Includes bibliographical references and index
  • "Proceedings of the satellite symposium held in conjunction with the annual meeting of the Society for Neuroscience, Missouri Institute of Psychiatry, St. Louis, Missouri, November 4-5, 1978."
Carrier category
volume
Carrier category code
  • nc
Carrier MARC source
rdacarrier
Content category
text
Content type code
  • txt
Content type MARC source
rdacontent
Control code
4883636
Dimensions
26 cm
Extent
xv, 327 pages
Isbn
9780306401732
Lccn
79014523
Media category
unmediated
Media MARC source
rdamedia
Media type code
  • n
Other physical details
illustrations
Label
Modulators, mediators, and specifiers in brain function : interactions of neuropeptides, cyclic nucleotides, and phosphorproteins in mechanisms underlying neuronal activity, behavior, and neuropsychiatric disorders, edited by Y. H. Ehrlich [and others]
Publication
Note
  • Includes bibliographical references and index
  • "Proceedings of the satellite symposium held in conjunction with the annual meeting of the Society for Neuroscience, Missouri Institute of Psychiatry, St. Louis, Missouri, November 4-5, 1978."
Carrier category
volume
Carrier category code
  • nc
Carrier MARC source
rdacarrier
Content category
text
Content type code
  • txt
Content type MARC source
rdacontent
Control code
4883636
Dimensions
26 cm
Extent
xv, 327 pages
Isbn
9780306401732
Lccn
79014523
Media category
unmediated
Media MARC source
rdamedia
Media type code
  • n
Other physical details
illustrations

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