The Resource Nanoparticle mediated ablation of breast cancer cells using a nanosecond pulsed electric field

Nanoparticle mediated ablation of breast cancer cells using a nanosecond pulsed electric field

Label
Nanoparticle mediated ablation of breast cancer cells using a nanosecond pulsed electric field
Title
Nanoparticle mediated ablation of breast cancer cells using a nanosecond pulsed electric field
Creator
Author
Subject
Language
eng
Summary
In the past, both nanomaterials and various heating modalities have been researched as means for treating cancers. However, many of the current methodologies have the flaws of inconsistent tumor ablation and significant destruction of healthy cells. Based on research performed using constant radiofrequency electric fields and metallic nanoparticles (where cell necrosis is induced by the heating of these nanoparticles) we have developed a modality that simlarly uses functionalized metallic nanoparticles, specific for the T47D breast cancer cell line, and nanosecond pulsed electric fields as the hyperthermic inducer. Using both iron oxide and gold nanoparticles the results of our pilot studies indicated that up to 90% of the cancer cells were ablated given the optimal treatment parameters. These quantities of ablated cells were achieved using a cumulative exposure time 6 orders of magnitude less than most in vitro radiofrequency electric field studies
Cataloging source
MUU
http://library.link/vocab/creatorName
Burford, Christopher
Degree
M.S.
Dissertation note
Thesis
Dissertation year
2013.
Government publication
government publication of a state province territory dependency etc
Granting institution
University of Missouri--Columbia,
Index
no index present
Literary form
non fiction
Nature of contents
dictionaries
Label
Nanoparticle mediated ablation of breast cancer cells using a nanosecond pulsed electric field
Instantiates
Publication
Contributor
Thesis advisor
Note
Advisor: John A. Viator
Carrier category
online resource
Carrier category code
cr
Carrier MARC source
rdacarrier.
Content category
text
Content type code
txt
Content type MARC source
rdacontent.
Control code
876615807
Extent
1 online resource (v, 50 pages)
Form of item
online
Media category
computer
Media MARC source
rdamedia.
Media type code
c
Specific material designation
remote
System control number
(OCoLC)876615807
Label
Nanoparticle mediated ablation of breast cancer cells using a nanosecond pulsed electric field
Publication
Contributor
Thesis advisor
Note
Advisor: John A. Viator
Carrier category
online resource
Carrier category code
cr
Carrier MARC source
rdacarrier.
Content category
text
Content type code
txt
Content type MARC source
rdacontent.
Control code
876615807
Extent
1 online resource (v, 50 pages)
Form of item
online
Media category
computer
Media MARC source
rdamedia.
Media type code
c
Specific material designation
remote
System control number
(OCoLC)876615807

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