Coverart for item
The Resource Nanoscale imaging of synapses : new opportunities and concepts, edited by U. Valentin Nägerl, Antoine Triller

Nanoscale imaging of synapses : new opportunities and concepts, edited by U. Valentin Nägerl, Antoine Triller

Label
Nanoscale imaging of synapses : new opportunities and concepts
Title
Nanoscale imaging of synapses
Title remainder
new opportunities and concepts
Statement of responsibility
edited by U. Valentin Nägerl, Antoine Triller
Contributor
Editor
Subject
Genre
Language
eng
Summary
Synapses underlie rapid and flexible neural communication in the brain and they hold the key to understanding higher brain functions in health and disease. Because they are very small and highly dynamic, it is very difficult to study them with traditional techniques. Fortunately, recent ground-breaking advances in microscopy have greatly improved our ability to image synapses at the nanoscale, even down to the level of single molecules. Authored by leading practitioners and developers in the field, this volume focuses on the nanoscale analysis of the molecular and structural organization and dynamics of synapses of the central nervous system, utilizing superresolution (e.g. PALM, STORM, STED) and other advanced methods (e.g. EM tomography, optogenetics, FLIM). It explains the basic principles behind the various nanoscale imaging modalities, how they are implemented and what their scope and limitations are, while also highlighting several exciting new research opportunities for synapse research enabled by them
Member of
Cataloging source
GW5XE
Dewey number
573.8/5
Index
index present
LC call number
QP364
Literary form
non fiction
Nature of contents
dictionaries
http://library.link/vocab/relatedWorkOrContributorName
  • Nägerl, U. Valentin
  • Triller, Antoine
Series statement
Neuromethods,
Series volume
volume 84
http://library.link/vocab/subjectName
Synapses
Label
Nanoscale imaging of synapses : new opportunities and concepts, edited by U. Valentin Nägerl, Antoine Triller
Instantiates
Publication
Note
Includes index
Antecedent source
unknown
Carrier category
online resource
Carrier category code
  • cr
Carrier MARC source
rdacarrier
Color
multicolored
Content category
text
Content type code
  • txt
Content type MARC source
rdacontent
Contents
Nanoscale imaging of protein molecules at the postsynaptic densit -- Electron tomography for the study of synaptic ultrastructure in fixed brain sections -- Time-resolved electron microscopy: coupling optogenetics with high-pressure freezing -- Investigating AMPA receptors diffusion and nanoscale organization at synapses with high density single molecule tracking methods -- Visualising the ultra-structures and dynamics of synapses by single molecule nanoscopy -- Live-cell PALM of intracellular proteins in neurons -- Monitoring nanoscale mobility of small molecules with time-resolved fluorescence anisotropy imaging -- Imaging signalling transduction in single dendritic spines -- Imaging-based measures of synaptic tenacity -- Zooming in on the (peri)synaptic extracellular matrix -- Two-photon STED microscopy for imaging synapses and glia in acute brain slices
Control code
870646694
Dimensions
unknown
Extent
1 online resource (x, 231 pages).
File format
unknown
Form of item
online
Isbn
9781461491798
Level of compression
unknown
Media category
computer
Media MARC source
rdamedia
Media type code
  • c
Other control number
10.1007/978-1-4614-9179-8
Quality assurance targets
not applicable
Reformatting quality
unknown
Sound
unknown sound
Specific material designation
remote
System control number
(OCoLC)870646694
Label
Nanoscale imaging of synapses : new opportunities and concepts, edited by U. Valentin Nägerl, Antoine Triller
Publication
Note
Includes index
Antecedent source
unknown
Carrier category
online resource
Carrier category code
  • cr
Carrier MARC source
rdacarrier
Color
multicolored
Content category
text
Content type code
  • txt
Content type MARC source
rdacontent
Contents
Nanoscale imaging of protein molecules at the postsynaptic densit -- Electron tomography for the study of synaptic ultrastructure in fixed brain sections -- Time-resolved electron microscopy: coupling optogenetics with high-pressure freezing -- Investigating AMPA receptors diffusion and nanoscale organization at synapses with high density single molecule tracking methods -- Visualising the ultra-structures and dynamics of synapses by single molecule nanoscopy -- Live-cell PALM of intracellular proteins in neurons -- Monitoring nanoscale mobility of small molecules with time-resolved fluorescence anisotropy imaging -- Imaging signalling transduction in single dendritic spines -- Imaging-based measures of synaptic tenacity -- Zooming in on the (peri)synaptic extracellular matrix -- Two-photon STED microscopy for imaging synapses and glia in acute brain slices
Control code
870646694
Dimensions
unknown
Extent
1 online resource (x, 231 pages).
File format
unknown
Form of item
online
Isbn
9781461491798
Level of compression
unknown
Media category
computer
Media MARC source
rdamedia
Media type code
  • c
Other control number
10.1007/978-1-4614-9179-8
Quality assurance targets
not applicable
Reformatting quality
unknown
Sound
unknown sound
Specific material designation
remote
System control number
(OCoLC)870646694

Library Locations

    • Ellis LibraryBorrow it
      1020 Lowry Street, Columbia, MO, 65201, US
      38.944491 -92.326012
Processing Feedback ...