Coverart for item
The Resource Neurodegeneration : exploring commonalities across diseases : workshop summary, Miriam Davis and Clare Stroud, rapporteurs ; Forum on Neuroscience and Nervous System Disorders, Board on Health Sciences Policy, Institute of Medicine of the National Academies

Neurodegeneration : exploring commonalities across diseases : workshop summary, Miriam Davis and Clare Stroud, rapporteurs ; Forum on Neuroscience and Nervous System Disorders, Board on Health Sciences Policy, Institute of Medicine of the National Academies

Label
Neurodegeneration : exploring commonalities across diseases : workshop summary
Title
Neurodegeneration
Title remainder
exploring commonalities across diseases : workshop summary
Statement of responsibility
Miriam Davis and Clare Stroud, rapporteurs ; Forum on Neuroscience and Nervous System Disorders, Board on Health Sciences Policy, Institute of Medicine of the National Academies
Creator
Contributor
Sponsoring body
Subject
Genre
Language
eng
Summary
"Neurodegeneration: Exploring Commonalities Across Diseases is the summary of a workshop hosted by the Institute of Medicine's (IOM's) Forum on Neuroscience and Nervous System Disorders in Spring 2012 to explore commonalities across neurodegenerative diseases such as Alzheimer's disease, Parkinson's disease, amyotrophic lateral sclerosis (ALS), and frontotemporal dementia (FTD). Participants from academia; pharmaceutical and biotechnology industries; government agencies such as the National Institutes of Health and the U.S. Department of Veterans Affairs (VA); patient advocacy groups; and private foundations presented and identified potential opportunities for collaboration across the respective research and development communities. This report identifies and discusses commonalities related to genetic and cellular mechanisms, identifies areas of fundamental science needed to facilitate therapeutics development, and explores areas of potential collaboration among the respective research communities. Neurodegenerative diseases, such as Alzheimer's disease, Parkinson's disease, ALS, and FTD, are becoming increasingly prevalent in the United States due to an aging population. Implications are grave for quality of life and health care costs. Research on neurodegenerative diseases has expanded greatly over the past four decades. Nevertheless, fundamental questions remain about the biology of these diseases, and further insights into the mechanisms of these diseases would help to inform the development of effective means to prevent and to efficiently treat them. Recent findings have revealed certain commonalities in genetic and cellular mechanisms across neurodegenerative diseases. These findings suggest that it might be valuable - at least in some cases - to change the traditional way of studying these diseases by no longer seeing each as an independent entity, but rather as clinical variants of common cellular and molecular biological defects. This approach could help enhance basic scientific understanding of neurodegenerative disease, and could help with the development of biomarkers and new therapeutics."
Member of
Cataloging source
MMU
Dewey number
616.8/047
Illustrations
illustrations
Index
no index present
LC call number
R856.A2
LC item number
.N487 2013
Literary form
non fiction
http://bibfra.me/vocab/lite/meetingDate
2012
http://bibfra.me/vocab/lite/meetingName
Neurodegeneration: Opportunities for Collaboration Across Disease-Specific Research and Development Communities (Workshop)
Nature of contents
  • dictionaries
  • bibliography
NLM call number
WL 358.5
http://bibfra.me/vocab/relation/rapporteur
  • dL0G31WNya8
  • j6A4gshEj3Y
http://library.link/vocab/relatedWorkOrContributorName
  • Davis, Miriam
  • Stroud, Clare
  • Institute of Medicine (U.S.)
http://library.link/vocab/subjectName
  • Nervous system
  • Biology
  • Biomedical Research
  • Biomedical Research
  • Neurodegenerative Diseases
  • Research Design
  • Neurodegenerative Diseases
  • Biomedical Research
  • Research Design
  • HEALTH & FITNESS
  • MEDICAL
  • MEDICAL
  • MEDICAL
  • MEDICAL
  • Biology
  • Nervous system
Label
Neurodegeneration : exploring commonalities across diseases : workshop summary, Miriam Davis and Clare Stroud, rapporteurs ; Forum on Neuroscience and Nervous System Disorders, Board on Health Sciences Policy, Institute of Medicine of the National Academies
Instantiates
Publication
Copyright
Bibliography note
Includes bibliographical references
Carrier category
online resource
Carrier category code
cr
Carrier MARC source
rdacarrier
Content category
text
Content type code
txt
Content type MARC source
rdacontent
Contents
Introduction -- Rationale for exploring commonalities across neurodegenerative diseases -- Protein aggregation -- Transmissibility -- Mitochondrial pathology -- Errors in RNA -- Closing remarks
Control code
866949752
Extent
1 online resource (106 pages)
Form of item
online
Isbn
9780309285681
Lccn
2014395561
Media category
computer
Media MARC source
rdamedia
Media type code
c
Other physical details
illustrations (chiefly color)
Specific material designation
remote
System control number
(OCoLC)866949752
Label
Neurodegeneration : exploring commonalities across diseases : workshop summary, Miriam Davis and Clare Stroud, rapporteurs ; Forum on Neuroscience and Nervous System Disorders, Board on Health Sciences Policy, Institute of Medicine of the National Academies
Publication
Copyright
Bibliography note
Includes bibliographical references
Carrier category
online resource
Carrier category code
cr
Carrier MARC source
rdacarrier
Content category
text
Content type code
txt
Content type MARC source
rdacontent
Contents
Introduction -- Rationale for exploring commonalities across neurodegenerative diseases -- Protein aggregation -- Transmissibility -- Mitochondrial pathology -- Errors in RNA -- Closing remarks
Control code
866949752
Extent
1 online resource (106 pages)
Form of item
online
Isbn
9780309285681
Lccn
2014395561
Media category
computer
Media MARC source
rdamedia
Media type code
c
Other physical details
illustrations (chiefly color)
Specific material designation
remote
System control number
(OCoLC)866949752

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