Coverart for item
The Resource Novel chemical tools to study ion channel biology, Christopher Ahern, Stephan Pless, editors

Novel chemical tools to study ion channel biology, Christopher Ahern, Stephan Pless, editors

Label
Novel chemical tools to study ion channel biology
Title
Novel chemical tools to study ion channel biology
Statement of responsibility
Christopher Ahern, Stephan Pless, editors
Contributor
Editor
Subject
Language
eng
Summary
"This volume describes chemical approaches to assess ion channel structure, function and pharmacology. Topics discussed include the use of engineered ionizable side chains to obtain information on permeation pathways and the local environment; the modification of engineered cysteine side chains, including cysteine scanning mutagenesis and the attachment of fluorescent probes and bio-reactive tethers; and the nascent use of genetic code expansion, evaluating its applications to ion channel and membrane proteins. This comprehensive text provides multifaceted perspectives on the great diversity of state-of-the-art methods which take advantage of the ever-expanding chemical toolbox to study ion channel biology. Capturing the contributions and innovations of renowned laboratory researchers in transmembrane protein study for the first time, this book is comprehensive in scope. It covers a wide array of experimental approaches: photochemistry, novel biological tools, and innovative spectroscopy, all combined with traditional techniques of electrophysiology and molecular biology. Novel Chemical Tools to Study Ion Channel Biology, part of the bestselling Advances in Experimental Medicine and Biology series is ideal for researchers and advanced students interested in biochemistry, biophysics, fluorometry, electrophysiology, and chemical biology"--Back cover
Member of
Cataloging source
YDXCP
Dewey number
571.6/4
Illustrations
illustrations
Index
index present
LC call number
QH603.I54
Literary form
non fiction
Nature of contents
bibliography
NLM call number
QU 55.7
NLM item number
.N937 2015
http://library.link/vocab/relatedWorkOrContributorName
  • Ahern, Christopher
  • Pless, Stephan
Series statement
Advances in experimental medicine and biology,
Series volume
volume 869
http://library.link/vocab/subjectName
  • Ion channels
  • Electrophysiology
  • Electrophysiology
  • Ion Channels
  • Fluorometry
  • Photochemistry
  • Electrophysiology
  • Ion channels
Label
Novel chemical tools to study ion channel biology, Christopher Ahern, Stephan Pless, editors
Instantiates
Publication
Copyright
Bibliography note
Includes bibliographical references and index
Carrier category
volume
Carrier category code
  • nc
Carrier MARC source
rdacarrier.
Content category
text
Content type code
  • txt
Content type MARC source
rdacontent.
Contents
Introduction / Stephan A. Pless, Christopher A. Ahern -- Engineered ionizable side chains / Gisela D. Cymes, Claudio Grosman -- Cysteine modification: probing channel structure, function and conformational change / Myles H. Akabas -- Functional site-directed fluorometry / Michael Priest, Francisco Bezanilla -- Bioreactive tethers / Karen Mruk, William R. Kobertz -- Flipping the photoswitch: ion channels under light control / Catherine K. McKenzie, Inmaculada Sanchez-Romero, Harald Janovjak -- Incorporation of non-canonical amino acids / Lilia Leisle, Francis Valiyaveetil, Ryan A. Mehl, Christopher A. Ahern
Control code
907652458
Dimensions
25 cm
Extent
viii, 154 pages
Isbn
9781493928446
Lccn
2015945350
Media category
unmediated
Media MARC source
rdamedia.
Media type code
  • n
Other physical details
illustrations (some color)
System control number
(OCoLC)907652458
Label
Novel chemical tools to study ion channel biology, Christopher Ahern, Stephan Pless, editors
Publication
Copyright
Bibliography note
Includes bibliographical references and index
Carrier category
volume
Carrier category code
  • nc
Carrier MARC source
rdacarrier.
Content category
text
Content type code
  • txt
Content type MARC source
rdacontent.
Contents
Introduction / Stephan A. Pless, Christopher A. Ahern -- Engineered ionizable side chains / Gisela D. Cymes, Claudio Grosman -- Cysteine modification: probing channel structure, function and conformational change / Myles H. Akabas -- Functional site-directed fluorometry / Michael Priest, Francisco Bezanilla -- Bioreactive tethers / Karen Mruk, William R. Kobertz -- Flipping the photoswitch: ion channels under light control / Catherine K. McKenzie, Inmaculada Sanchez-Romero, Harald Janovjak -- Incorporation of non-canonical amino acids / Lilia Leisle, Francis Valiyaveetil, Ryan A. Mehl, Christopher A. Ahern
Control code
907652458
Dimensions
25 cm
Extent
viii, 154 pages
Isbn
9781493928446
Lccn
2015945350
Media category
unmediated
Media MARC source
rdamedia.
Media type code
  • n
Other physical details
illustrations (some color)
System control number
(OCoLC)907652458

Library Locations

    • J. Otto Lottes Health Sciences LibraryBorrow it
      1 Hospital Dr, Columbia, MO, 65201, US
      38.939544 -92.328377
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