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The Resource Oxford textbook of cancer biology, edited by Francesco Pezzella, Mahvash Tavassoli, David J. Kerr

Oxford textbook of cancer biology, edited by Francesco Pezzella, Mahvash Tavassoli, David J. Kerr

Label
Oxford textbook of cancer biology
Title
Oxford textbook of cancer biology
Statement of responsibility
edited by Francesco Pezzella, Mahvash Tavassoli, David J. Kerr
Title variation
Cancer biology
Contributor
Editor
Subject
Language
eng
Summary
"The study of the biology of tumours has grown to become markedly interdisciplinary, involving chemists, statisticians, epidemiologists, mathematicians, bioinformaticians, and computer scientists alongside biologists, geneticists, and clinicians. The Oxford Textbook of Cancer Biology brings together the most up-to-date developments from different branches of research into one coherent volume, providing a comprehensive and current account of this rapidlyevolving field.Structured in eight sections, the book starts with a review of the development and biology of multi-cellular organisms, how they maintain a healthy homeostasis in an individual, and a description of the molecular basis of cancer development. The book then illustrates, as once cells become neoplastic, their signalling network is altered and pathological behaviour follows. It explores the changes that cancer cells can induce in nearby normal tissue, the new relationship established between themand the stroma, and the interaction between the immune system and tumour growth. The authors illustrate the contribution provided by high throughput techniques to map cancer at different levels, from genomic sequencing to cellular metabolic functions, and how information technology, with its vastamounts of data, is integrated with traditional cell biology to provide a global view of the disease. The effect of the different types of treatments on the biology of the neoplastic cells are explored to understand on the one side, why some treatments succeed, and on the other, how they can affect the biology of resistant and recurrent disease. The book concludes by summarizing what we know to date about cancer, and in what direction our understanding of cancer is moving"--Publisher's description
Member of
Cataloging source
N$T
Dewey number
616.99/4
Illustrations
illustrations
Index
index present
LC call number
RC268.4
Literary form
non fiction
Nature of contents
  • dictionaries
  • bibliography
NLM call number
QZ 203
http://library.link/vocab/relatedWorkOrContributorName
  • Pezzella, Francesco
  • Tavassoli, Mahvash
  • Kerr, David J.
Series statement
Oxford textbooks in oncology
http://library.link/vocab/subjectName
  • Cancer
  • Cancer cells
  • Neoplastic Processes
  • Neoplasms
  • Neoplasms
  • Treatment Outcome
  • Biological Phenomena
  • Cancer cells
  • Cancer
  • HEALTH & FITNESS
  • MEDICAL
  • MEDICAL
  • MEDICAL
  • MEDICAL
Label
Oxford textbook of cancer biology, edited by Francesco Pezzella, Mahvash Tavassoli, David J. Kerr
Instantiates
Publication
Bibliography note
Includes bibliographical references and index
Carrier category
online resource
Carrier category code
  • cr
Carrier MARC source
rdacarrier
Content category
text
Content type code
  • txt
Content type MARC source
rdacontent
Contents
Section I: The multicellular organism. The multicellular organism and cancer -- DNA repair and genome integrity -- Evolution and cancer -- Section II: The aetiology of cancer. Genetics and genetic instability in cancer -- Epigenetics -- Viral carcinogenesis-an overview -- Chemical carcinogens -- Radiation as a carcinogen -- Section III: How the cancer cell works. Growth factors and associated signalling pathways in tumour progression and in cancer treatment -- Hormones and cancer -- Oncogenesis and tumour suppression -- The signalling pathways in cancer -- Cell cycle control -- Cancer and cell death -- Telomerase and immortalization -- Cancer metabolism -- Chaperones and protein quality control in the neoplastic process -- Oxygen and cancer: The response to hypoxia -- Invasion, metastasis, and tumour dormancy -- Cancer stem cells -- Section IV: Cancer microenvironment. Cancer-associated stroma -- Blood vessels and cancer -- Cancer immunology -- Section V: Global vision of cancer. Molecular profiling in cancer research and personalized medicine -- Proteomics and metabolomics applications in cancer biology -- Cancer systems biology: From molecular profiles to pathways, signalling networks, and therapeutic vulnerabilities -- Cancer biology through immunohistology -- Section VI: The biology of cancer treatment. Principles of chemotherapy -- Immunotherapy and tumour resistance to immune-mediated control and elimination -- Biological effect of radiotherapy on cancer cells -- Section VII: Conclusions. Benign tumours: The forgotten neoplasms -- Conclusions: Cancer biology, a moveable feast
Control code
1100767637
Edition
First edition.
Extent
1 online resource (xvi, 483 pages)
Form of item
online
Isbn
9780191084867
Media category
computer
Media MARC source
rdamedia
Media type code
  • c
Other physical details
illustrations (chiefly color).
Specific material designation
remote
System control number
(OCoLC)1100767637
Label
Oxford textbook of cancer biology, edited by Francesco Pezzella, Mahvash Tavassoli, David J. Kerr
Publication
Bibliography note
Includes bibliographical references and index
Carrier category
online resource
Carrier category code
  • cr
Carrier MARC source
rdacarrier
Content category
text
Content type code
  • txt
Content type MARC source
rdacontent
Contents
Section I: The multicellular organism. The multicellular organism and cancer -- DNA repair and genome integrity -- Evolution and cancer -- Section II: The aetiology of cancer. Genetics and genetic instability in cancer -- Epigenetics -- Viral carcinogenesis-an overview -- Chemical carcinogens -- Radiation as a carcinogen -- Section III: How the cancer cell works. Growth factors and associated signalling pathways in tumour progression and in cancer treatment -- Hormones and cancer -- Oncogenesis and tumour suppression -- The signalling pathways in cancer -- Cell cycle control -- Cancer and cell death -- Telomerase and immortalization -- Cancer metabolism -- Chaperones and protein quality control in the neoplastic process -- Oxygen and cancer: The response to hypoxia -- Invasion, metastasis, and tumour dormancy -- Cancer stem cells -- Section IV: Cancer microenvironment. Cancer-associated stroma -- Blood vessels and cancer -- Cancer immunology -- Section V: Global vision of cancer. Molecular profiling in cancer research and personalized medicine -- Proteomics and metabolomics applications in cancer biology -- Cancer systems biology: From molecular profiles to pathways, signalling networks, and therapeutic vulnerabilities -- Cancer biology through immunohistology -- Section VI: The biology of cancer treatment. Principles of chemotherapy -- Immunotherapy and tumour resistance to immune-mediated control and elimination -- Biological effect of radiotherapy on cancer cells -- Section VII: Conclusions. Benign tumours: The forgotten neoplasms -- Conclusions: Cancer biology, a moveable feast
Control code
1100767637
Edition
First edition.
Extent
1 online resource (xvi, 483 pages)
Form of item
online
Isbn
9780191084867
Media category
computer
Media MARC source
rdamedia
Media type code
  • c
Other physical details
illustrations (chiefly color).
Specific material designation
remote
System control number
(OCoLC)1100767637

Library Locations

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      38.939544 -92.328377
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