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The Resource Peptide nucleic acids : methods and protocols, edited by Peter E. Nielsen, Daniel H. Appella

Peptide nucleic acids : methods and protocols, edited by Peter E. Nielsen, Daniel H. Appella

Label
Peptide nucleic acids : methods and protocols
Title
Peptide nucleic acids
Title remainder
methods and protocols
Statement of responsibility
edited by Peter E. Nielsen, Daniel H. Appella
Contributor
Copyright holder
Editor
Subject
Genre
Language
eng
Summary
Exemplifying and illustrating recent exciting advances in PNA chemistry, the second edition of Peptide Nucleic Acids: Methods and Protocols serves as a vital complement to the first edition of the book. Since the discovery of peptide nucleic acids, many interesting new derivatives and analogues in terms of nucleic acid recognition specificity and affinity have emerged. Also, as this detailed volume presents, great ingenuity in exploiting the unique properties of PNAs for a wide variety of applications within drug discovery, medical diagnostics, chemical biology and nanotechnology has unfolded. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and key tips on troubleshooting and avoiding known pitfalls. Peptide Nucleic Acids: Methods and Protocols, Second Edition serves as a source of useful specific methods and protocols as well as a source of inspiration for future developments
Member of
Cataloging source
UKMGB
Dewey number
572.65
Illustrations
illustrations
Index
index present
LC call number
QP624.P4
LC item number
P47 2014
Literary form
non fiction
Nature of contents
bibliography
http://library.link/vocab/relatedWorkOrContributorDate
1951-
http://library.link/vocab/relatedWorkOrContributorName
  • Nielsen, Peter E.
  • Appella, Daniel
  • Springer Science+Business Media
Series statement
  • Methods in molecular biology,
  • Springer protocols,
Series volume
1050
http://library.link/vocab/subjectName
  • Peptides
  • Nucleic acids
  • Peptide Nucleic Acids
Label
Peptide nucleic acids : methods and protocols, edited by Peter E. Nielsen, Daniel H. Appella
Instantiates
Publication
Copyright
Bibliography note
Includes bibliographical references and index
Carrier category
volume
Carrier category code
  • nc
Carrier MARC source
rdacarrier.
Content category
text
Content type code
  • txt
Content type MARC source
rdacontent.
Contents
1. MiniPEG-[gamma]PNA / Arunava Manna, Srinivas Rapireddy, Raman Babal and Danith H. Ly -- 2. Cyclopentane peptide nucleic acids / Ethan A. Englund, Ning Zhang, and Daniel H. Appella -- 3. Chiral PNAs with constrained open-chain backbones / Roberto Corradini, Tullia Tedeschi, Stefano Sforza and Rosangela Marchelli -- 4. Synthesis, characterization, and evaluation of radiometal-containing peptide nucleic acids / Holger Stephan, Christian Foerster, and Gilles Gasser -- 5. Preparation of metal-containing peptide nucleic acid bioconjugates on the solid phase / Gilles Gasser -- 6. Formation and characterization of PNA-containing heteroquadruplexes / Bruce A. Armitage -- 7. Sequence selective recognition of double-stranded RNA using triple helix-forming peptide nucleic acids / Thomas Zengeya, Pankaj Gupta, and Eriks Rozners -- 8. Assembly of PNA-tagged small molecules, peptides, and carbohydrates onto DNA templates : programming the combinatorial pairing and inter-ligand distance / Nicolas Winssinger, Katarzyna Gorska, Mihai Ciobanu, Jean Pierre Daguer and Sofia Barluenga -- 9. Site-selective scission of human genome using PNA-based artificial restriction DNA cutter / Kenichiro Ito and Makoto Komiyama -- 10. PNA openers and their applications for bacterial DNA diagnostics / Irina V. Smolina and Maxim D. Frank-Kamenetskii -- 11. DNA-templated native chemical ligation of functionalized peptide nucleic acids : a versatile tool for single base-specific detection of nucleic acids / Alexander Roloff, Simon Ficht, Christian Dose and Oliver Seitz -- 12. Use of peptide nucleic acids (PNAs) for genotyping by solution and surface methods / Stefano Sforza, Tullia Tedeschi, Mariangela Bencivenni, Alessandro Tonelli, Roberto Corradini and Rosangela Marchelli -- 13. Analysis of PNA hybridization by surface plasmon resonance / Bruce A. Armitage -- 14. PNA fluorescent in situ hybridization (FISH) for rapid microbiology and cytogenetic analysis / Henrik Stender, Brett Williams, and James Coull -- 15. Rapid miRNA imaging in cells using fluorogenic templated Staudinger reaction between PNA-based probes / Katarzyna Gorska and Nicolas Winssinger -- 16. Cellular delivery of peptide nucleic acids (PNAs) / Takehiko Shiraishi and Peter E. Nielsen -- 17. Peptide nucleic acid-mediated recombination for targeted genomic repair and modification / Erica B. Schleifman and Peter M. Glazer -- 18. Antisense effects of PNAs in bacteria / Shan Goh, Jem Stach, and Liam Good
Control code
868380884
Dimensions
26 cm
Edition
Second edition.
Extent
x, 239 pages
Isbn
9781627035521
Lccn
2013954403
Media category
unmediated
Media MARC source
rdamedia.
Media type code
  • n
Other physical details
illustrations (some color)
System control number
(OCoLC)868380884
Label
Peptide nucleic acids : methods and protocols, edited by Peter E. Nielsen, Daniel H. Appella
Publication
Copyright
Bibliography note
Includes bibliographical references and index
Carrier category
volume
Carrier category code
  • nc
Carrier MARC source
rdacarrier.
Content category
text
Content type code
  • txt
Content type MARC source
rdacontent.
Contents
1. MiniPEG-[gamma]PNA / Arunava Manna, Srinivas Rapireddy, Raman Babal and Danith H. Ly -- 2. Cyclopentane peptide nucleic acids / Ethan A. Englund, Ning Zhang, and Daniel H. Appella -- 3. Chiral PNAs with constrained open-chain backbones / Roberto Corradini, Tullia Tedeschi, Stefano Sforza and Rosangela Marchelli -- 4. Synthesis, characterization, and evaluation of radiometal-containing peptide nucleic acids / Holger Stephan, Christian Foerster, and Gilles Gasser -- 5. Preparation of metal-containing peptide nucleic acid bioconjugates on the solid phase / Gilles Gasser -- 6. Formation and characterization of PNA-containing heteroquadruplexes / Bruce A. Armitage -- 7. Sequence selective recognition of double-stranded RNA using triple helix-forming peptide nucleic acids / Thomas Zengeya, Pankaj Gupta, and Eriks Rozners -- 8. Assembly of PNA-tagged small molecules, peptides, and carbohydrates onto DNA templates : programming the combinatorial pairing and inter-ligand distance / Nicolas Winssinger, Katarzyna Gorska, Mihai Ciobanu, Jean Pierre Daguer and Sofia Barluenga -- 9. Site-selective scission of human genome using PNA-based artificial restriction DNA cutter / Kenichiro Ito and Makoto Komiyama -- 10. PNA openers and their applications for bacterial DNA diagnostics / Irina V. Smolina and Maxim D. Frank-Kamenetskii -- 11. DNA-templated native chemical ligation of functionalized peptide nucleic acids : a versatile tool for single base-specific detection of nucleic acids / Alexander Roloff, Simon Ficht, Christian Dose and Oliver Seitz -- 12. Use of peptide nucleic acids (PNAs) for genotyping by solution and surface methods / Stefano Sforza, Tullia Tedeschi, Mariangela Bencivenni, Alessandro Tonelli, Roberto Corradini and Rosangela Marchelli -- 13. Analysis of PNA hybridization by surface plasmon resonance / Bruce A. Armitage -- 14. PNA fluorescent in situ hybridization (FISH) for rapid microbiology and cytogenetic analysis / Henrik Stender, Brett Williams, and James Coull -- 15. Rapid miRNA imaging in cells using fluorogenic templated Staudinger reaction between PNA-based probes / Katarzyna Gorska and Nicolas Winssinger -- 16. Cellular delivery of peptide nucleic acids (PNAs) / Takehiko Shiraishi and Peter E. Nielsen -- 17. Peptide nucleic acid-mediated recombination for targeted genomic repair and modification / Erica B. Schleifman and Peter M. Glazer -- 18. Antisense effects of PNAs in bacteria / Shan Goh, Jem Stach, and Liam Good
Control code
868380884
Dimensions
26 cm
Edition
Second edition.
Extent
x, 239 pages
Isbn
9781627035521
Lccn
2013954403
Media category
unmediated
Media MARC source
rdamedia.
Media type code
  • n
Other physical details
illustrations (some color)
System control number
(OCoLC)868380884

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