Coverart for item
The Resource Permutation testing for isotonic inference on association studies in genetics, Rosa Arboretti [and others]

Permutation testing for isotonic inference on association studies in genetics, Rosa Arboretti [and others]

Label
Permutation testing for isotonic inference on association studies in genetics
Title
Permutation testing for isotonic inference on association studies in genetics
Statement of responsibility
Rosa Arboretti [and others]
Creator
Subject
Language
eng
Summary
The purpose of this book is to illustrate a new statistical approach to test allelic association and genotype-specific effects in the genetic study of diseases. There are some parametric and non-parametric methods available for this purpose. We deal with population-based association studies, but comparisons with other methods will also be drawn, analysing the advantages and disadvantages of each one, particularly with regard to power properties with small sample sizes. In this framework we will work out some nonparametric statistical permutation tests and likelihood-based tests to perform case-control analyses to study allelic association between marker, disease-gene and environmental factors. Permutation tests, in particular, will be extended to multivariate and more complex studies, where we deal with several genes and several alleles together. Furthermore, we show simulations under different assumptions on the genetic model and analyse real data sets by simply studying one locus with the permutation test
Member of
Cataloging source
GW5XE
http://library.link/vocab/creatorName
Arboretti, Rosa
Dewey number
616/.042
Index
no index present
LC call number
RB155
LC item number
.A73 2011eb
Literary form
non fiction
Nature of contents
  • dictionaries
  • bibliography
Series statement
SpringerBriefs in statistics
http://library.link/vocab/subjectName
  • Medical genetics
  • Human genetics
  • Human genetics
  • Medical genetics
Label
Permutation testing for isotonic inference on association studies in genetics, Rosa Arboretti [and others]
Instantiates
Publication
Antecedent source
unknown
Bibliography note
Includes bibliographical references
Carrier category
online resource
Carrier category code
  • cr
Carrier MARC source
rdacarrier
Color
multicolored
Content category
text
Content type code
  • txt
Content type MARC source
rdacontent
Contents
Introduction -- Association Studies in Genetics -- The Nonparametric Permutation Methodology -- Statistical Problems of Allelic Association -- Power and Sample Size Simulations -- Case Study -- Conclusions -- References
Control code
768427939
Dimensions
unknown
Extent
1 online resource (vi, 72 pages).
File format
unknown
Form of item
online
Isbn
9783642205842
Level of compression
unknown
Media category
computer
Media MARC source
rdamedia
Media type code
  • c
Quality assurance targets
not applicable
Reformatting quality
unknown
Sound
unknown sound
Specific material designation
remote
System control number
(OCoLC)768427939
Label
Permutation testing for isotonic inference on association studies in genetics, Rosa Arboretti [and others]
Publication
Antecedent source
unknown
Bibliography note
Includes bibliographical references
Carrier category
online resource
Carrier category code
  • cr
Carrier MARC source
rdacarrier
Color
multicolored
Content category
text
Content type code
  • txt
Content type MARC source
rdacontent
Contents
Introduction -- Association Studies in Genetics -- The Nonparametric Permutation Methodology -- Statistical Problems of Allelic Association -- Power and Sample Size Simulations -- Case Study -- Conclusions -- References
Control code
768427939
Dimensions
unknown
Extent
1 online resource (vi, 72 pages).
File format
unknown
Form of item
online
Isbn
9783642205842
Level of compression
unknown
Media category
computer
Media MARC source
rdamedia
Media type code
  • c
Quality assurance targets
not applicable
Reformatting quality
unknown
Sound
unknown sound
Specific material designation
remote
System control number
(OCoLC)768427939

Library Locations

    • Ellis LibraryBorrow it
      1020 Lowry Street, Columbia, MO, 65201, US
      38.944491 -92.326012
Processing Feedback ...