Coverart for item
The Resource Protein-protein interactions : methods and applications, edited by Haian Fu

Protein-protein interactions : methods and applications, edited by Haian Fu

Label
Protein-protein interactions : methods and applications
Title
Protein-protein interactions
Title remainder
methods and applications
Statement of responsibility
edited by Haian Fu
Contributor
Subject
Genre
Language
eng
Summary
Proteins continuously interact with each other to determine cell fate. Consequently, an examination of just when such protein-protein interactions occur and how they are controlled is essential for understanding the molecular mechanism of biological processes, elucidating the molecular basis of diseases, and identifying potential targets for therapeutic interventions. In Protein-Protein Interactions: Methods and Applications, leading experts describe in detail their highly successful biochemical, biophysical, genetic, and computational techniques for studying these interactions. Their readily reproducible methods demonstrate how to identify protein interaction partners, qualitatively or quantitatively measure protein-protein interactions, monitor protein-protein interactions as they occur in living cells, and determine interaction interfaces. The techniques described utilize a variety of cutting-edge technologies, including surface plasmon resonance (SRP), fluorescence resonance energy transfer (FRET), fluorescence polarization (FP), isothermal titration calorimetry (ITC), circular dichroism (CD), protein fragment complementation assays (PCA), various two-hybrid systems, and proteomics- and bioinformatics-based approaches, such as the Scansite program for computational analysis. Each time-tested protocol includes a background introduction outlining the principle behind the technique, lists of equipment and reagents, and tips on troubleshooting and avoiding known pitfalls. Authoritative and highly practical, Protein-Protein Interactions: Methods and Applications offers both beginning and experienced investigators a full range of the powerful tools needed for deciphering how proteins interact to form biological networks, as well as for unraveling protein-protein interactions in disease in the search for novel therapeutic targets
Member of
Cataloging source
COO
Dewey number
572/.6
Illustrations
illustrations
Index
index present
Language note
English
LC call number
QP551.5
LC item number
.P76 2004
Literary form
non fiction
Nature of contents
  • dictionaries
  • bibliography
NLM call number
  • W1
  • QU 25
NLM item number
  • ME9616J v.261 2004
  • P96695 2004
http://library.link/vocab/relatedWorkOrContributorName
Fu, Haian
Series statement
Methods in molecular biology
Series volume
261
http://library.link/vocab/subjectName
  • Protein-protein interactions
  • Protein Binding
  • Proteins
  • SCIENCE
  • Protein-protein interactions
Label
Protein-protein interactions : methods and applications, edited by Haian Fu
Instantiates
Publication
Bibliography note
Includes bibliographical references and index
Carrier category
online resource
Carrier category code
  • cr
Carrier MARC source
rdacarrier
Content category
text
Content type code
  • txt
Content type MARC source
rdacontent
Contents
Protein-Protein Interactions: Methods and Applications; Contents; Contributors
Control code
55594606
Dimensions
unknown
Extent
1 online resource (xvi, 532 pages)
Form of item
online
Isbn
9781592597628
Media category
computer
Media MARC source
rdamedia
Media type code
  • c
Other physical details
illustrations (some color).
Specific material designation
remote
System control number
(OCoLC)55594606
Label
Protein-protein interactions : methods and applications, edited by Haian Fu
Publication
Bibliography note
Includes bibliographical references and index
Carrier category
online resource
Carrier category code
  • cr
Carrier MARC source
rdacarrier
Content category
text
Content type code
  • txt
Content type MARC source
rdacontent
Contents
Protein-Protein Interactions: Methods and Applications; Contents; Contributors
Control code
55594606
Dimensions
unknown
Extent
1 online resource (xvi, 532 pages)
Form of item
online
Isbn
9781592597628
Media category
computer
Media MARC source
rdamedia
Media type code
  • c
Other physical details
illustrations (some color).
Specific material designation
remote
System control number
(OCoLC)55594606

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