Coverart for item
The Resource Screening : methods for experimentation in industry, drug discovery, and genetics, Angela Dean, Susan Lewis, editors

Screening : methods for experimentation in industry, drug discovery, and genetics, Angela Dean, Susan Lewis, editors

Label
Screening : methods for experimentation in industry, drug discovery, and genetics
Title
Screening
Title remainder
methods for experimentation in industry, drug discovery, and genetics
Statement of responsibility
Angela Dean, Susan Lewis, editors
Contributor
Subject
Language
eng
Summary
The process of discovery in science and technology may require investigation of a large number of features, such as factors, genes or molecules. In Screening, statistically designed experiments and analyses of the resulting data sets are used to identify efficiently the few features that determine key properties of the system under study. This book brings together accounts by leading international experts that are essential reading for those working in fields such as industrial quality improvement, engineering research and development, genetic and medical screening, drug discovery, and computer simulation of manufacturing systems or economic models. Our aim is to promote cross-fertilization of ideas and methods through detailed explanations, a variety of examples and extensive references. Topics cover both physical and computer simulated experiments. They include screening methods for detecting factors that affect the value of a response or its variability, and for choosing between various different response models. Screening for disease in blood samples, for genes linked to a disease and for new compounds in the search for effective drugs are also described. Statistical techniques include Bayesian and frequentist methods of data analysis, algorithmic methods for both the design and analysis of experiments, and the construction of fractional factorial designs and orthogonal arrays. The material is accessible to graduate and research statisticians, and to engineers and chemists with a working knowledge of statistical ideas and techniques. It will be of interest to practitioners and researchers who wish to learn about useful methodologies from within their own area as well as methodologies that can be translated from one area to another. Angela Dean is Professor of Statistics at The Ohio State University, USA. She is a Fellow of the American Statistical Association, the Institute of Mathematical Statistics, and an elected member of the International Statistical Institute. Her research focuses on the construction of efficient designs for factorial experiments in industry and marketing. She is co-author of the textbook Design and Analysis of Experiments and has served on the editorial boards of the Journal of the Royal Statistical Society and Technometrics. Susan Lewis is a Professor of Statistics at the University of Southampton, UK, and Deputy Director of the Southampton Statistical Sciences Research Institute. She has research interests in screening, design algorithms and the design and analysis of experiments in industry. She was awarded the Greenfield Industrial Medal by the Royal Statistical Society in 2005. She has served the Society as a Vice-President and a Member of Council, as well as a former Editor of the Journal of the Royal Statistical Society, Series C (Applied Statistics)
Is part of
Cataloging source
GW5XE
Dewey number
610.727
Illustrations
illustrations
Index
index present
LC call number
R852
LC item number
.S37 2006eb
Literary form
non fiction
Nature of contents
  • dictionaries
  • bibliography
NLM call number
  • 2006 L-045
  • W 20.5
NLM item number
S433 2006
http://library.link/vocab/relatedWorkOrContributorName
  • Dean, Angela
  • Lewis, Susan M
http://library.link/vocab/subjectName
  • Medicine
  • Medical screening
  • Research Design
  • Computer Simulation
  • Drug Evaluation, Preclinical
  • Genetic Testing
  • Models, Statistical
  • MEDICAL
  • Medical screening
  • Medicine
  • Medical screening
  • Medicine
  • Screening
Label
Screening : methods for experimentation in industry, drug discovery, and genetics, Angela Dean, Susan Lewis, editors
Instantiates
Publication
Bibliography note
Includes bibliographical references and index
Carrier category
online resource
Carrier category code
  • cr
Carrier MARC source
rdacarrier
Color
multicolored
Content category
text
Content type code
  • txt
Content type MARC source
rdacontent
Contents
  • Design and analysis of screening experiments with microarrays
  • Paola Sebastiani, Joanna Jeneralczuk, Marco F. Ramoni
  • Screening for differential gene expressions from microarray data
  • Jason C. Hsu, Jane Y. Chang, Tao Wang
  • Projection properties of factorial designs for factor screening
  • Ching-Shui Cheng
  • Factor screening via supersaturated designs
  • Steven G. Gilmour
  • An overview of group factor screening
  • Max D. Morris
  • An overview of industrial screening experiments
  • Screening designs for model selection
  • William Li
  • Prior distributions for Bayesian analysis of screening experiments
  • Hugh Chipman
  • Analysis of orthogonal saturated designs
  • Daniel T. Voss, Weizhen Wang
  • Screening for the important factors in large discrete-event simulation models : sequential bifurcation and its applications
  • Jack P.C. Kleijnen, Bert Bettonvil, Fredrik Persson
  • Screening the input variables to a computer model via analysis of variance and visualization
  • Matthias Schonlau, William J. Welch
  • Douglas C. Montgomery, Cheryl L. Jennings
  • Screening experiments for dispersion effects
  • Dizza Bursztyn, David M. Steinberg
  • Pooling experiments for blood screening and drug discovery
  • Jacqueline M. Hughes-Oliver
  • Pharmaceutical drug discovery : designing the blockbuster drug
  • David Jesse Cummins
Control code
209911781
Dimensions
unknown
Extent
1 online resource (xv, 332 pages)
Form of item
online
Isbn
9780387280141
Media category
computer
Media MARC source
rdamedia
Media type code
  • c
Other physical details
illustrations
http://library.link/vocab/ext/overdrive/overdriveId
978-0-387-28013-4
Specific material designation
remote
System control number
(OCoLC)209911781
Label
Screening : methods for experimentation in industry, drug discovery, and genetics, Angela Dean, Susan Lewis, editors
Publication
Bibliography note
Includes bibliographical references and index
Carrier category
online resource
Carrier category code
  • cr
Carrier MARC source
rdacarrier
Color
multicolored
Content category
text
Content type code
  • txt
Content type MARC source
rdacontent
Contents
  • Design and analysis of screening experiments with microarrays
  • Paola Sebastiani, Joanna Jeneralczuk, Marco F. Ramoni
  • Screening for differential gene expressions from microarray data
  • Jason C. Hsu, Jane Y. Chang, Tao Wang
  • Projection properties of factorial designs for factor screening
  • Ching-Shui Cheng
  • Factor screening via supersaturated designs
  • Steven G. Gilmour
  • An overview of group factor screening
  • Max D. Morris
  • An overview of industrial screening experiments
  • Screening designs for model selection
  • William Li
  • Prior distributions for Bayesian analysis of screening experiments
  • Hugh Chipman
  • Analysis of orthogonal saturated designs
  • Daniel T. Voss, Weizhen Wang
  • Screening for the important factors in large discrete-event simulation models : sequential bifurcation and its applications
  • Jack P.C. Kleijnen, Bert Bettonvil, Fredrik Persson
  • Screening the input variables to a computer model via analysis of variance and visualization
  • Matthias Schonlau, William J. Welch
  • Douglas C. Montgomery, Cheryl L. Jennings
  • Screening experiments for dispersion effects
  • Dizza Bursztyn, David M. Steinberg
  • Pooling experiments for blood screening and drug discovery
  • Jacqueline M. Hughes-Oliver
  • Pharmaceutical drug discovery : designing the blockbuster drug
  • David Jesse Cummins
Control code
209911781
Dimensions
unknown
Extent
1 online resource (xv, 332 pages)
Form of item
online
Isbn
9780387280141
Media category
computer
Media MARC source
rdamedia
Media type code
  • c
Other physical details
illustrations
http://library.link/vocab/ext/overdrive/overdriveId
978-0-387-28013-4
Specific material designation
remote
System control number
(OCoLC)209911781

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