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The Resource Steroid receptor methods : protocols and assays, edited by Benjamin A. Lieberman

Steroid receptor methods : protocols and assays, edited by Benjamin A. Lieberman

Label
Steroid receptor methods : protocols and assays
Title
Steroid receptor methods
Title remainder
protocols and assays
Statement of responsibility
edited by Benjamin A. Lieberman
Contributor
Subject
Genre
Language
eng
Summary
Research into steroid receptor biology holds great promise for the treatment of cancer and endocrine disorders and for elucidating the fundamental biological mechanisms of gene expression. In Steroid Receptor Methods: Protocols and Assays, a distinguished team of principal investigators and their associates describe in step-by-step detail a cross-section of the latest research techniques available for studying the endocrine system. As a basis for sophisticated biochemical analysis of receptor properties, the contributors provide methods for the production and purification of a variety of receptors, including progesterone, glucocorticoid, and androgen. Other protocols allow the reader to experiment with DNA-binding characteristics and hormone-binding assays and with the use of combinatorial chemistry for drug discovery. A series of novel methods utilizing the latest advances in immunochemistry, yeast two-hybrid screening, and fluorescence are included for the detection and analysis of a variety of cellular proteins that influence steroid receptor effectiveness. Finally, a discussion by example presents the most current bioinformatics tools and analytical techniques. Timely and highly accessible, Steroid Receptor Methods: Protocols and Assays provides biochemists and molecular biologists studying endocrine systems with a full range of the powerful tools needed for elucidating protein interactions with receptors and DNA, as well as for drug discovery
Member of
Is part of
Cataloging source
COO
Dewey number
612.4/05
Illustrations
illustrations
Index
index present
Language note
English
LC call number
QP572.S7
LC item number
S756 2001
Literary form
non fiction
Nature of contents
  • dictionaries
  • bibliography
NLM call number
  • W1
  • WK 25
NLM item number
  • ME9616J v.176 2001
  • S839 2001
http://library.link/vocab/relatedWorkOrContributorName
Lieberman, Benjamin A
Series statement
Methods in molecular biology
Series volume
176
http://library.link/vocab/subjectName
  • Steroid hormones
  • Receptors, Steroid
  • Steroids
  • MEDICAL
  • SCIENCE
  • Steroid hormones
Label
Steroid receptor methods : protocols and assays, edited by Benjamin A. Lieberman
Instantiates
Publication
Bibliography note
Includes bibliographical references and index
Carrier category
online resource
Carrier category code
  • cr
Carrier MARC source
rdacarrier
Content category
text
Content type code
  • txt
Content type MARC source
rdacontent
Contents
pt. I. Bioinformatics -- 1. Bioinformatics of Nuclear Receptors / Mark Danielsen -- 2. Phylogenetic Inference and Parsimony Analysis / Llewellyn D. Densmore III -- pt. II. Purification Protocols -- 3. Expression and Purification of Recombinant Human Progesterone Receptor in Baculovirus and Bacterial Systems / Vida Senkus Melvin and Dean P. Edwards -- 4. High-Yield Purification of Functionally Active Glucocorticoid Receptor / Terace M. Fletcher, Barbour S. Warren and Christopher T. Baumann [and others] -- 5. Production and Purification of Histidine-Tagged Dihydrotestosterone-Bound Full-Length Human Androgen Receptor / Mingmin Liao and Elizabeth M. Wilson -- 6. Large Scale Production of Nuclear Receptor Ligand-Binding Domains / Li-Zhi Mi and Fraydoon Rastinejad -- 7. Physical Structure of Nuclear Receptor-DNA Complexes / Scott A. Chasse and Fraydoon Rastinejad
Control code
50175103
Dimensions
unknown
Extent
1 online resource (xiv, 381 pages)
Form of item
online
Isbn
9781592591152
Media category
computer
Media MARC source
rdamedia
Media type code
  • c
Other control number
10.1385/1592591159.
Other physical details
illustrations.
http://library.link/vocab/ext/overdrive/overdriveId
springerp
Specific material designation
remote
System control number
(OCoLC)50175103
Label
Steroid receptor methods : protocols and assays, edited by Benjamin A. Lieberman
Publication
Bibliography note
Includes bibliographical references and index
Carrier category
online resource
Carrier category code
  • cr
Carrier MARC source
rdacarrier
Content category
text
Content type code
  • txt
Content type MARC source
rdacontent
Contents
pt. I. Bioinformatics -- 1. Bioinformatics of Nuclear Receptors / Mark Danielsen -- 2. Phylogenetic Inference and Parsimony Analysis / Llewellyn D. Densmore III -- pt. II. Purification Protocols -- 3. Expression and Purification of Recombinant Human Progesterone Receptor in Baculovirus and Bacterial Systems / Vida Senkus Melvin and Dean P. Edwards -- 4. High-Yield Purification of Functionally Active Glucocorticoid Receptor / Terace M. Fletcher, Barbour S. Warren and Christopher T. Baumann [and others] -- 5. Production and Purification of Histidine-Tagged Dihydrotestosterone-Bound Full-Length Human Androgen Receptor / Mingmin Liao and Elizabeth M. Wilson -- 6. Large Scale Production of Nuclear Receptor Ligand-Binding Domains / Li-Zhi Mi and Fraydoon Rastinejad -- 7. Physical Structure of Nuclear Receptor-DNA Complexes / Scott A. Chasse and Fraydoon Rastinejad
Control code
50175103
Dimensions
unknown
Extent
1 online resource (xiv, 381 pages)
Form of item
online
Isbn
9781592591152
Media category
computer
Media MARC source
rdamedia
Media type code
  • c
Other control number
10.1385/1592591159.
Other physical details
illustrations.
http://library.link/vocab/ext/overdrive/overdriveId
springerp
Specific material designation
remote
System control number
(OCoLC)50175103

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