Coverart for item
The Resource Structural genomics and drug discovery : methods and protocols, edited by Wayne F. Anderson

Structural genomics and drug discovery : methods and protocols, edited by Wayne F. Anderson

Label
Structural genomics and drug discovery : methods and protocols
Title
Structural genomics and drug discovery
Title remainder
methods and protocols
Statement of responsibility
edited by Wayne F. Anderson
Contributor
Editor
Subject
Genre
Language
eng
Summary
Structural Genomics and Drug Discovery: Methods and Protocols focuses on high throughput structure determination methods and how they can be applied to lay the groundwork for structure aided drug discovery. The methods and protocols that are described can be applied in any laboratory interested in using detailed structural information to advance the initial stages of drug discovery. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and key tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Structural Genomics and Drug Discovery: Methods and Protocols seeks to aid scientists in the further study into structural genomics approach as an efficient initial step toward drug discovery and the methods described will be useful to anyone interested in moving in this direction
Member of
Cataloging source
GW5XE
Dewey number
576.5
Illustrations
illustrations
Index
index present
LC call number
QH447
Literary form
non fiction
Nature of contents
  • dictionaries
  • bibliography
NLM call number
QV 745
http://library.link/vocab/relatedWorkOrContributorName
Anderson, Wayne F.
Series statement
Methods in molecular biology, 1940-6029
Series volume
1140
http://library.link/vocab/subjectName
  • Genomics
  • Drug development
  • Genomics
  • Drug Discovery
  • High-Throughput Screening Assays
  • Drug development
  • Genomics
Label
Structural genomics and drug discovery : methods and protocols, edited by Wayne F. Anderson
Instantiates
Publication
Copyright
Antecedent source
unknown
Bibliography note
Includes bibliographical references and index
Carrier category
online resource
Carrier category code
  • cr
Carrier MARC source
rdacarrier
Color
multicolored
Content category
text
Content type code
  • txt
Content type MARC source
rdacontent
Contents
  • Automated Cell-free Protein Production Methods for Structural Studies
  • Parallel Protein Purification
  • Oxidative Refolding from Inclusion Bodies
  • High throughput Crystallization Screening
  • Screening Proteins for NMR Suitability
  • Salvage or Recovery of Failed Targets by in situ Proteolysis
  • Salvage of Failed Protein Targets by Reductive Alkylation
  • Salvage or Recovery of Failed Targets by Mutagenesis to Reduce Surface Entropy
  • Data Collection for Crystallographic Structure Determination
  • Structure, Determination, Refinement, and Validation
  • Data Management in the Modern Structural Biology and Biomedical Research Environment
  • Virtual High-Throughput Ligand Screening
  • Ligand Screening using Fluorescence Thermal Shift Analysis (FTS)
  • Ligand Screening using Enzymatic Assays
  • Ligand Screening using NMR
  • Screening Ligands by X-ray Crystallography
  • Case Study Structural Genomics and Human Protein Kinases
  • Structural Genomics of Human Proteins
  • Target Selection for Structural Genomics of Infectious Diseases
  • Selecting Targets from Eukaryotic Parasites for Structural Genomics and Drug Discovery
  • High Throughput Cloning for Biophysical Applications
  • Expression and Solubility Testing in a High Throughput Environment
  • Protein Production for Structural Genomics Using E. coli Expression
  • Eukaryotic Expression Systems for Structural Studies
Control code
872563371
Dimensions
unknown
Extent
1 online resource (xv, 344 pages)
File format
unknown
Form of item
online
Isbn
9781493903535
Level of compression
unknown
Media category
computer
Media MARC source
rdamedia
Media type code
  • c
Other control number
10.1007/978-1-4939-0354-2
Other physical details
illustrations (some color).
Quality assurance targets
not applicable
Reformatting quality
unknown
Sound
unknown sound
Specific material designation
remote
System control number
(OCoLC)872563371
Label
Structural genomics and drug discovery : methods and protocols, edited by Wayne F. Anderson
Publication
Copyright
Antecedent source
unknown
Bibliography note
Includes bibliographical references and index
Carrier category
online resource
Carrier category code
  • cr
Carrier MARC source
rdacarrier
Color
multicolored
Content category
text
Content type code
  • txt
Content type MARC source
rdacontent
Contents
  • Automated Cell-free Protein Production Methods for Structural Studies
  • Parallel Protein Purification
  • Oxidative Refolding from Inclusion Bodies
  • High throughput Crystallization Screening
  • Screening Proteins for NMR Suitability
  • Salvage or Recovery of Failed Targets by in situ Proteolysis
  • Salvage of Failed Protein Targets by Reductive Alkylation
  • Salvage or Recovery of Failed Targets by Mutagenesis to Reduce Surface Entropy
  • Data Collection for Crystallographic Structure Determination
  • Structure, Determination, Refinement, and Validation
  • Data Management in the Modern Structural Biology and Biomedical Research Environment
  • Virtual High-Throughput Ligand Screening
  • Ligand Screening using Fluorescence Thermal Shift Analysis (FTS)
  • Ligand Screening using Enzymatic Assays
  • Ligand Screening using NMR
  • Screening Ligands by X-ray Crystallography
  • Case Study Structural Genomics and Human Protein Kinases
  • Structural Genomics of Human Proteins
  • Target Selection for Structural Genomics of Infectious Diseases
  • Selecting Targets from Eukaryotic Parasites for Structural Genomics and Drug Discovery
  • High Throughput Cloning for Biophysical Applications
  • Expression and Solubility Testing in a High Throughput Environment
  • Protein Production for Structural Genomics Using E. coli Expression
  • Eukaryotic Expression Systems for Structural Studies
Control code
872563371
Dimensions
unknown
Extent
1 online resource (xv, 344 pages)
File format
unknown
Form of item
online
Isbn
9781493903535
Level of compression
unknown
Media category
computer
Media MARC source
rdamedia
Media type code
  • c
Other control number
10.1007/978-1-4939-0354-2
Other physical details
illustrations (some color).
Quality assurance targets
not applicable
Reformatting quality
unknown
Sound
unknown sound
Specific material designation
remote
System control number
(OCoLC)872563371

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      38.944491 -92.326012
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