The Resource Structural genomics and drug discovery : methods and protocols, edited by Wayne F. Anderson
Structural genomics and drug discovery : methods and protocols, edited by Wayne F. Anderson
Resource Information
The item Structural genomics and drug discovery : methods and protocols, edited by Wayne F. Anderson represents a specific, individual, material embodiment of a distinct intellectual or artistic creation found in University of Missouri Libraries.This item is available to borrow from 1 library branch.
Resource Information
The item Structural genomics and drug discovery : methods and protocols, edited by Wayne F. Anderson represents a specific, individual, material embodiment of a distinct intellectual or artistic creation found in University of Missouri Libraries.
This item is available to borrow from 1 library branch.
- Summary
- Structural Genomics and Drug Discovery: Methods and Protocols focuses on high throughput structure determination methods and how they can be applied to lay the groundwork for structure aided drug discovery. The methods and protocols that are described can be applied in any laboratory interested in using detailed structural information to advance the initial stages of drug discovery. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and key tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Structural Genomics and Drug Discovery: Methods and Protocols seeks to aid scientists in the further study into structural genomics approach as an efficient initial step toward drug discovery and the methods described will be useful to anyone interested in moving in this direction
- Language
- eng
- Extent
- 1 online resource (xv, 344 pages)
- Contents
-
- Automated Cell-free Protein Production Methods for Structural Studies
- Parallel Protein Purification
- Oxidative Refolding from Inclusion Bodies
- High throughput Crystallization Screening
- Screening Proteins for NMR Suitability
- Salvage or Recovery of Failed Targets by in situ Proteolysis
- Salvage of Failed Protein Targets by Reductive Alkylation
- Salvage or Recovery of Failed Targets by Mutagenesis to Reduce Surface Entropy
- Data Collection for Crystallographic Structure Determination
- Structure, Determination, Refinement, and Validation
- Data Management in the Modern Structural Biology and Biomedical Research Environment
- Virtual High-Throughput Ligand Screening
- Ligand Screening using Fluorescence Thermal Shift Analysis (FTS)
- Ligand Screening using Enzymatic Assays
- Ligand Screening using NMR
- Screening Ligands by X-ray Crystallography
- Case Study Structural Genomics and Human Protein Kinases
- Structural Genomics of Human Proteins
- Target Selection for Structural Genomics of Infectious Diseases
- Selecting Targets from Eukaryotic Parasites for Structural Genomics and Drug Discovery
- High Throughput Cloning for Biophysical Applications
- Expression and Solubility Testing in a High Throughput Environment
- Protein Production for Structural Genomics Using E. coli Expression
- Eukaryotic Expression Systems for Structural Studies
- Isbn
- 9781493903535
- Label
- Structural genomics and drug discovery : methods and protocols
- Title
- Structural genomics and drug discovery
- Title remainder
- methods and protocols
- Statement of responsibility
- edited by Wayne F. Anderson
- Language
- eng
- Summary
- Structural Genomics and Drug Discovery: Methods and Protocols focuses on high throughput structure determination methods and how they can be applied to lay the groundwork for structure aided drug discovery. The methods and protocols that are described can be applied in any laboratory interested in using detailed structural information to advance the initial stages of drug discovery. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and key tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Structural Genomics and Drug Discovery: Methods and Protocols seeks to aid scientists in the further study into structural genomics approach as an efficient initial step toward drug discovery and the methods described will be useful to anyone interested in moving in this direction
- Cataloging source
- GW5XE
- Dewey number
- 576.5
- Illustrations
- illustrations
- Index
- index present
- LC call number
- QH447
- Literary form
- non fiction
- Nature of contents
-
- dictionaries
- bibliography
- NLM call number
- QV 745
- http://library.link/vocab/relatedWorkOrContributorName
- Anderson, Wayne F.
- Series statement
- Methods in molecular biology, 1940-6029
- Series volume
- 1140
- http://library.link/vocab/subjectName
-
- Genomics
- Drug development
- Genomics
- Drug Discovery
- High-Throughput Screening Assays
- Drug development
- Genomics
- Label
- Structural genomics and drug discovery : methods and protocols, edited by Wayne F. Anderson
- Antecedent source
- unknown
- Bibliography note
- Includes bibliographical references and index
- Carrier category
- online resource
- Carrier category code
-
- cr
- Carrier MARC source
- rdacarrier
- Color
- multicolored
- Content category
- text
- Content type code
-
- txt
- Content type MARC source
- rdacontent
- Contents
-
- Automated Cell-free Protein Production Methods for Structural Studies
- Parallel Protein Purification
- Oxidative Refolding from Inclusion Bodies
- High throughput Crystallization Screening
- Screening Proteins for NMR Suitability
- Salvage or Recovery of Failed Targets by in situ Proteolysis
- Salvage of Failed Protein Targets by Reductive Alkylation
- Salvage or Recovery of Failed Targets by Mutagenesis to Reduce Surface Entropy
- Data Collection for Crystallographic Structure Determination
- Structure, Determination, Refinement, and Validation
- Data Management in the Modern Structural Biology and Biomedical Research Environment
- Virtual High-Throughput Ligand Screening
- Ligand Screening using Fluorescence Thermal Shift Analysis (FTS)
- Ligand Screening using Enzymatic Assays
- Ligand Screening using NMR
- Screening Ligands by X-ray Crystallography
- Case Study Structural Genomics and Human Protein Kinases
- Structural Genomics of Human Proteins
- Target Selection for Structural Genomics of Infectious Diseases
- Selecting Targets from Eukaryotic Parasites for Structural Genomics and Drug Discovery
- High Throughput Cloning for Biophysical Applications
- Expression and Solubility Testing in a High Throughput Environment
- Protein Production for Structural Genomics Using E. coli Expression
- Eukaryotic Expression Systems for Structural Studies
- Control code
- 872563371
- Dimensions
- unknown
- Extent
- 1 online resource (xv, 344 pages)
- File format
- unknown
- Form of item
- online
- Isbn
- 9781493903535
- Level of compression
- unknown
- Media category
- computer
- Media MARC source
- rdamedia
- Media type code
-
- c
- Other control number
- 10.1007/978-1-4939-0354-2
- Other physical details
- illustrations (some color).
- Quality assurance targets
- not applicable
- Reformatting quality
- unknown
- Sound
- unknown sound
- Specific material designation
- remote
- System control number
- (OCoLC)872563371
- Label
- Structural genomics and drug discovery : methods and protocols, edited by Wayne F. Anderson
- Antecedent source
- unknown
- Bibliography note
- Includes bibliographical references and index
- Carrier category
- online resource
- Carrier category code
-
- cr
- Carrier MARC source
- rdacarrier
- Color
- multicolored
- Content category
- text
- Content type code
-
- txt
- Content type MARC source
- rdacontent
- Contents
-
- Automated Cell-free Protein Production Methods for Structural Studies
- Parallel Protein Purification
- Oxidative Refolding from Inclusion Bodies
- High throughput Crystallization Screening
- Screening Proteins for NMR Suitability
- Salvage or Recovery of Failed Targets by in situ Proteolysis
- Salvage of Failed Protein Targets by Reductive Alkylation
- Salvage or Recovery of Failed Targets by Mutagenesis to Reduce Surface Entropy
- Data Collection for Crystallographic Structure Determination
- Structure, Determination, Refinement, and Validation
- Data Management in the Modern Structural Biology and Biomedical Research Environment
- Virtual High-Throughput Ligand Screening
- Ligand Screening using Fluorescence Thermal Shift Analysis (FTS)
- Ligand Screening using Enzymatic Assays
- Ligand Screening using NMR
- Screening Ligands by X-ray Crystallography
- Case Study Structural Genomics and Human Protein Kinases
- Structural Genomics of Human Proteins
- Target Selection for Structural Genomics of Infectious Diseases
- Selecting Targets from Eukaryotic Parasites for Structural Genomics and Drug Discovery
- High Throughput Cloning for Biophysical Applications
- Expression and Solubility Testing in a High Throughput Environment
- Protein Production for Structural Genomics Using E. coli Expression
- Eukaryotic Expression Systems for Structural Studies
- Control code
- 872563371
- Dimensions
- unknown
- Extent
- 1 online resource (xv, 344 pages)
- File format
- unknown
- Form of item
- online
- Isbn
- 9781493903535
- Level of compression
- unknown
- Media category
- computer
- Media MARC source
- rdamedia
- Media type code
-
- c
- Other control number
- 10.1007/978-1-4939-0354-2
- Other physical details
- illustrations (some color).
- Quality assurance targets
- not applicable
- Reformatting quality
- unknown
- Sound
- unknown sound
- Specific material designation
- remote
- System control number
- (OCoLC)872563371
Subject
- Drug Discovery -- methods
- Drug development
- Drug development
- Drug development
- Genomics
- Genomics
- Genomics
- Genomics -- methods
- High-Throughput Screening Assays -- methods
- Laboratory Manual
Genre
Member of
- Methods in molecular biology (Clifton, N.J.), v. 1140
- Methods in molecular biology (Clifton, N.J.), v. 1140.
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<div class="citation" vocab="http://schema.org/"><i class="fa fa-external-link-square fa-fw"></i> Data from <span resource="http://link.library.missouri.edu/portal/Structural-genomics-and-drug-discovery--methods/umcsoKUZyhM/" typeof="Book http://bibfra.me/vocab/lite/Item"><span property="name http://bibfra.me/vocab/lite/label"><a href="http://link.library.missouri.edu/portal/Structural-genomics-and-drug-discovery--methods/umcsoKUZyhM/">Structural genomics and drug discovery : methods and protocols, edited by Wayne F. Anderson</a></span> - <span property="potentialAction" typeOf="OrganizeAction"><span property="agent" typeof="LibrarySystem http://library.link/vocab/LibrarySystem" resource="http://link.library.missouri.edu/"><span property="name http://bibfra.me/vocab/lite/label"><a property="url" href="http://link.library.missouri.edu/">University of Missouri Libraries</a></span></span></span></span></div>
