The Resource Study of anti-cancer effect of winter worm and summer grass on Mcf-7 human breast cancer cells, by Tongtong Xu, (electronic resource)

Study of anti-cancer effect of winter worm and summer grass on Mcf-7 human breast cancer cells, by Tongtong Xu, (electronic resource)

Label
Study of anti-cancer effect of winter worm and summer grass on Mcf-7 human breast cancer cells
Title
Study of anti-cancer effect of winter worm and summer grass on Mcf-7 human breast cancer cells
Statement of responsibility
by Tongtong Xu
Creator
Contributor
Thesis advisor
Subject
Genre
Language
eng
Summary
Winter worm and summer grass (WWSG) is one of the most valued traditional Chinese medicines for fighting cancer, increasing longevity, and improving immunity. It consists of the entomopathogenic fungus Cordyceps sinensis and its natural lepidopteran host Hepialus armoricanus. Using the water extract of Cordyceps militaris, a sibling species of C. sinensis cultivated on an artificial host the silkworm Bombyx mori pupae, we have found that the C. militaris extract inhibited growth of MCF-7 human breast cancer cells in a dose- and time-dependent manner. The inhibitory effect of the C. militaris extract on MCF-7 cells was via an apoptosis cascade by inducing the expression of pro-apoptotic genes and by suppressing anti-apoptotic marker genes. Moreover, the C. militaris extract also inhibits DNA methyltransferase transcription, suggesting that the reduced cancer suppressor gene methylation might lead to the recovery of tumor-suppressor gene expression and eventually to the inhibition of tumor cell growth
Cataloging source
MUU
http://library.link/vocab/creatorDate
1977-
http://library.link/vocab/creatorName
Xu, Tongtong
Degree
M.S.
Dissertation year
2008.
Granting institution
University of Missouri-Columbia
Illustrations
illustrations
Index
no index present
Literary form
non fiction
Nature of contents
  • dictionaries
  • bibliography
  • theses
http://library.link/vocab/relatedWorkOrContributorName
Song, Qisheng
http://library.link/vocab/subjectName
  • Medicine, Chinese
  • Breast
  • Entomopathogenic fungi
  • Cordyceps
  • Tumors
Target audience
specialized
Label
Study of anti-cancer effect of winter worm and summer grass on Mcf-7 human breast cancer cells, by Tongtong Xu, (electronic resource)
Instantiates
Publication
Note
  • The entire dissertation/thesis text is included in the research.pdf file; the official abstract appears in the short.pdf file (which also appears in the research.pdf); a non-technical general description, or public abstract, appears in the public.pdf file
  • Title from title screen of research.pdf file (viewed on July 9, 2009)
Bibliography note
Includes bibliographical references
Carrier category
online resource
Carrier category code
  • cr
Carrier MARC source
rdacarrier
Color
mixed
Content category
text
Content type code
  • txt
Content type MARC source
rdacontent
Control code
423395329
Dimensions
unknown
Form of item
electronic
Media category
computer
Media MARC source
rdamedia
Media type code
  • c
Specific material designation
remote
System control number
(OCoLC)423395329
System details
Mode of access: World Wide Web
Label
Study of anti-cancer effect of winter worm and summer grass on Mcf-7 human breast cancer cells, by Tongtong Xu, (electronic resource)
Publication
Note
  • The entire dissertation/thesis text is included in the research.pdf file; the official abstract appears in the short.pdf file (which also appears in the research.pdf); a non-technical general description, or public abstract, appears in the public.pdf file
  • Title from title screen of research.pdf file (viewed on July 9, 2009)
Bibliography note
Includes bibliographical references
Carrier category
online resource
Carrier category code
  • cr
Carrier MARC source
rdacarrier
Color
mixed
Content category
text
Content type code
  • txt
Content type MARC source
rdacontent
Control code
423395329
Dimensions
unknown
Form of item
electronic
Media category
computer
Media MARC source
rdamedia
Media type code
  • c
Specific material designation
remote
System control number
(OCoLC)423395329
System details
Mode of access: World Wide Web

Library Locations

  • Ellis LibraryBorrow it
    1020 Lowry Street, Columbia, MO, 65201, US
    38.944491 -92.326012
  • Engineering Library & Technology CommonsBorrow it
    W2001 Lafferre Hall, Columbia, MO, 65211, US
    38.946102 -92.330125
  • Fisher Delta Research CenterBorrow it
    2-64 Agricultural Bldg, Columbia, MO, 65201, US
    38.958397 -92.303491
  • Geological Sciences LibraryBorrow it
    201 Geological Sciences, Columbia, MO, 65211, US
    38.947375 -92.329062
  • J. Otto Lottes Health Sciences LibraryBorrow it
    1 Hospital Dr, Columbia, MO, 65201, US
    38.939544 -92.328377
  • Journalism LibraryBorrow it
    102 Reynolds Jrnlism Institute, Columbia, MO, 65211, US
    38.947290 -92.328025
  • Mathematical Sciences LibraryBorrow it
    104 Ellis Library, Columbia, MO, 65201, US
    38.944377 -92.326537
  • University ArchivesBorrow it
    Columbia, MO, 65201, US
  • University Archives McAlester AnnexBorrow it
    703 Lewis Hall, Columbia, MO, 65211, US
    38.934630 -92.342290
  • University of Missouri Libraries DepositoryBorrow it
    2908 Lemone Blvd, Columbia, MO, 65211, US
    38.919360 -92.291620
  • Zalk Veterinary Medical LibraryBorrow it
    Veterinary Medicine West, Columbia, MO, 65211, US
    38.941099 -92.317911
Processing Feedback ...