Borrow it
Coverart for item
The Resource Synthetic gene networks : methods and protocols, edited by Wilfried Weber, Martin Fussenegger

Synthetic gene networks : methods and protocols, edited by Wilfried Weber, Martin Fussenegger

Contributor
Summary
The rapid expansion of synthetic biology is due to the design and construction of synthetic gene networks that have opened many new avenues in fundamental and applied research. Synthetic Gene Networks: Methods and Protocols provides the necessary information to design and construct synthetic gene networks in different host backgrounds. Divided into four convenient sections, this volume focuses on design concepts to devise synthetic gene networks and how mathematical models can be applied to the predictable engineering of desired network features. The volume continues by highlighting the construction and validation of biologic tools, describing strategies to optimize and streamline the host cell for optimized network performance, and covering how optimally designed gene networks can be implemented in a large variety of host cells ranging from bacteria over yeast and insect cells to plant and mammalian cell culture. Written in the successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible protocols, and notes on troubleshooting and avoiding known pitfalls. Authoritative and easily accessible, Synthetic Gene Networks: Methods and Protocols serves as an invaluable resource for established biologists, engineers, and computer scientists or novices just entering into the rapidly growing field of synthetic biology
Language
eng
Work
Publication
Extent
1 online resource (xi, 393 pages)
Contents
  • In silico implementation of synthetic gene networks
  • Standardization in synthetic biology
  • Robust optimal design of synthetic biological networks
  • Predicting synthetic gene networks
  • Reprogramming a GFP reporter gene subjects it to complex lentiviral gene regulation
  • A high-throughput microfluidic method for generating and characterizing transcription factor mutant libraries
  • Identifying and optimizing intracellular protein-protein interactions using bacterial genetic selection
  • Zinc-finger nucleases-based genome engineering to generate isogenic human cell lines
  • RNA-based networks: Using RNA aptamers and ribozymes as synthetic genetic devices
  • MicroRNA circuits for transcriptional logic
  • Light-regulated gene expression in yeast
  • Light-controlled gene switches in mammalian cells
  • Expressed protein modifications: Making synthetic proteins
  • Using transcription machinery engineering to elicit complex cellular phenotypes
  • Streamlining of a pseudomonas putida genome using a combinatorial deletion method based on minitransposon insertion and the flp-FRT recombination system
  • Transposon-based and plasmid-based genetic tools for editing genomes of gram-negative bacteria
  • Synthetic networks: Oscillators and toggle switches for escherichia coli
  • Studying microbial communities in biofilms
  • Quantitative analysis of the spatiotemporal dynamics of a synthetic predator-prey ecosystem
  • Drosophila s2 schneider cells: A useful tool for rebuilding and redesigning approaches in synthetic biology
  • Synthetic gene networks in plant systems
  • Design and construction of synthetic gene networks in mammalian cells
  • Synthetic gene networks as blueprint for smart hydrogels
Isbn
9781617794124
Instance
Label
Synthetic gene networks : methods and protocols
Title
Synthetic gene networks
Title remainder
methods and protocols
Statement of responsibility
edited by Wilfried Weber, Martin Fussenegger
Contributor
Subject
Genre
Language
eng
Summary
The rapid expansion of synthetic biology is due to the design and construction of synthetic gene networks that have opened many new avenues in fundamental and applied research. Synthetic Gene Networks: Methods and Protocols provides the necessary information to design and construct synthetic gene networks in different host backgrounds. Divided into four convenient sections, this volume focuses on design concepts to devise synthetic gene networks and how mathematical models can be applied to the predictable engineering of desired network features. The volume continues by highlighting the construction and validation of biologic tools, describing strategies to optimize and streamline the host cell for optimized network performance, and covering how optimally designed gene networks can be implemented in a large variety of host cells ranging from bacteria over yeast and insect cells to plant and mammalian cell culture. Written in the successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible protocols, and notes on troubleshooting and avoiding known pitfalls. Authoritative and easily accessible, Synthetic Gene Networks: Methods and Protocols serves as an invaluable resource for established biologists, engineers, and computer scientists or novices just entering into the rapidly growing field of synthetic biology
Member of
Cataloging source
GW5XE
Dewey number
610.28
Illustrations
illustrations
Index
index present
Language note
English
LC call number
TA164
LC item number
.S96 2012
Literary form
non fiction
Nature of contents
  • dictionaries
  • bibliography
NLM call number
  • W1
  • QU 25
NLM item number
ME9616J v.813 2012
http://library.link/vocab/relatedWorkOrContributorDate
1974-
http://library.link/vocab/relatedWorkOrContributorName
  • Weber, Wilfried
  • Fussenegger, Martin
Series statement
Methods in molecular biology,
Series volume
813
http://library.link/vocab/subjectName
  • Synthetic biology
  • Bioengineering
  • Bioengineering
  • Regulatory Sequences, Nucleic Acid
  • Biology
  • Base Sequence
  • Engineering
  • Biological Science Disciplines
  • Natural Science Disciplines
  • Technology, Industry, and Agriculture
  • Genetic Structures
  • Genetic Phenomena
  • Disciplines and Occupations
  • Technology, Industry, Agriculture
  • Phenomena and Processes
  • Synthetic Biology
  • Gene Regulatory Networks
  • Bioengineering
  • Synthetic biology
Label
Synthetic gene networks : methods and protocols, edited by Wilfried Weber, Martin Fussenegger
Instantiates
Publication
Antecedent source
unknown
Bibliography note
Includes bibliographical references and index
Carrier category
online resource
Carrier category code
  • cr
Carrier MARC source
rdacarrier
Color
multicolored
Content category
text
Content type code
  • txt
Content type MARC source
rdacontent
Contents
In silico implementation of synthetic gene networks -- Standardization in synthetic biology -- Robust optimal design of synthetic biological networks -- Predicting synthetic gene networks -- Reprogramming a GFP reporter gene subjects it to complex lentiviral gene regulation -- A high-throughput microfluidic method for generating and characterizing transcription factor mutant libraries -- Identifying and optimizing intracellular protein-protein interactions using bacterial genetic selection -- Zinc-finger nucleases-based genome engineering to generate isogenic human cell lines -- RNA-based networks: Using RNA aptamers and ribozymes as synthetic genetic devices -- MicroRNA circuits for transcriptional logic -- Light-regulated gene expression in yeast -- Light-controlled gene switches in mammalian cells -- Expressed protein modifications: Making synthetic proteins -- Using transcription machinery engineering to elicit complex cellular phenotypes -- Streamlining of a pseudomonas putida genome using a combinatorial deletion method based on minitransposon insertion and the flp-FRT recombination system -- Transposon-based and plasmid-based genetic tools for editing genomes of gram-negative bacteria -- Synthetic networks: Oscillators and toggle switches for escherichia coli -- Studying microbial communities in biofilms -- Quantitative analysis of the spatiotemporal dynamics of a synthetic predator-prey ecosystem -- Drosophila s2 schneider cells: A useful tool for rebuilding and redesigning approaches in synthetic biology -- Synthetic gene networks in plant systems -- Design and construction of synthetic gene networks in mammalian cells -- Synthetic gene networks as blueprint for smart hydrogels
Control code
764650323
Dimensions
unknown
Extent
1 online resource (xi, 393 pages)
File format
unknown
Form of item
online
Isbn
9781617794124
Level of compression
unknown
Media category
computer
Media MARC source
rdamedia
Media type code
  • c
Other control number
10.1007/978-1-61779-412-4
Other physical details
illustrations.
Quality assurance targets
not applicable
Reformatting quality
unknown
Sound
unknown sound
Specific material designation
remote
System control number
(OCoLC)764650323
Label
Synthetic gene networks : methods and protocols, edited by Wilfried Weber, Martin Fussenegger
Publication
Antecedent source
unknown
Bibliography note
Includes bibliographical references and index
Carrier category
online resource
Carrier category code
  • cr
Carrier MARC source
rdacarrier
Color
multicolored
Content category
text
Content type code
  • txt
Content type MARC source
rdacontent
Contents
In silico implementation of synthetic gene networks -- Standardization in synthetic biology -- Robust optimal design of synthetic biological networks -- Predicting synthetic gene networks -- Reprogramming a GFP reporter gene subjects it to complex lentiviral gene regulation -- A high-throughput microfluidic method for generating and characterizing transcription factor mutant libraries -- Identifying and optimizing intracellular protein-protein interactions using bacterial genetic selection -- Zinc-finger nucleases-based genome engineering to generate isogenic human cell lines -- RNA-based networks: Using RNA aptamers and ribozymes as synthetic genetic devices -- MicroRNA circuits for transcriptional logic -- Light-regulated gene expression in yeast -- Light-controlled gene switches in mammalian cells -- Expressed protein modifications: Making synthetic proteins -- Using transcription machinery engineering to elicit complex cellular phenotypes -- Streamlining of a pseudomonas putida genome using a combinatorial deletion method based on minitransposon insertion and the flp-FRT recombination system -- Transposon-based and plasmid-based genetic tools for editing genomes of gram-negative bacteria -- Synthetic networks: Oscillators and toggle switches for escherichia coli -- Studying microbial communities in biofilms -- Quantitative analysis of the spatiotemporal dynamics of a synthetic predator-prey ecosystem -- Drosophila s2 schneider cells: A useful tool for rebuilding and redesigning approaches in synthetic biology -- Synthetic gene networks in plant systems -- Design and construction of synthetic gene networks in mammalian cells -- Synthetic gene networks as blueprint for smart hydrogels
Control code
764650323
Dimensions
unknown
Extent
1 online resource (xi, 393 pages)
File format
unknown
Form of item
online
Isbn
9781617794124
Level of compression
unknown
Media category
computer
Media MARC source
rdamedia
Media type code
  • c
Other control number
10.1007/978-1-61779-412-4
Other physical details
illustrations.
Quality assurance targets
not applicable
Reformatting quality
unknown
Sound
unknown sound
Specific material designation
remote
System control number
(OCoLC)764650323

Subject

Genre

Member of

Library Locations

    • Ellis LibraryBorrow it
      1020 Lowry Street, Columbia, MO, 65201, US
      38.944491 -92.326012

Library Links

Structured data from the Bibframe namespace is licensed under the Creative Commons Attribution 4.0 International License by University of Missouri Libraries. Additional terms may apply to data associated with third party namespaces.
Processing Feedback ...